Florida is currently home to 3751 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
NCT06089161
Recruiting
The purpose of this research is to see how effective the Personalized obstructive sleep apnea (OSA) Treatment Adherence Model called PRAISE is in helping the patient stick to the physician recommended OSA treatment plan Positive Airway Pressure (PAP).
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
07/25/2024
Locations: University of Miami, Miami, Florida
Conditions: Sleep Apnea
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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
NCT05975983
Recruiting
The goal of this clinical trial is to learn about INS018_055 in adults with Idiopathic Pulmonary Fibrosis (IPF). The primary objective is to evaluate the safety and tolerability of INS018_055 orally administered for up to 12 weeks in adult subjects with IPF compared to placebo.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/25/2024
Locations: Florida Lung Asthma and Sleep Specialist, Celebration, Florida
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
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Study to Evaluate the Safety and Tolerability of Single-Dose Intravenous (IV) Oritavancin
NCT05599295
Recruiting
This protocol describes a randomized, open-label study to evaluate the safety and tolerability of single-dose intravenous (IV) oritavancin diphosphate (oritavancin) versus standard of care (SoC) antibiotics for the treatment of pediatric subjects with acute bacterial skin and skin structure infections (ABSSSIs). This study involves two oritavancin products, ORBACTIV® and KIMYRSATM. Oritavancin is the active drug substance in both ORBACTIV and KIMYRSA. This study protocol distinguishes the diffe... Read More
Gender:
ALL
Ages:
Between 3 months and 17 years
Trial Updated:
07/25/2024
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Acute Bacterial Skin and Skin Structure Infection
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ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1
NCT05507203
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: Clinical Research Of Brandon, LLC, Brandon, Florida
Conditions: Ulcerative Colitis
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ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
NCT05507216
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: West Central Gastroenterology d/b/a Gastro Florida, Clearwater, Florida
Conditions: Ulcerative Colitis
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Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
NCT05381818
Recruiting
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery. It is known that breathing function decreases for a few days after surgery. in In this study, we want to see if exercising before surgery strengthens the breathing muscles and improves recovery after surgery.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/25/2024
Locations: University of Florida, Jacksonville, Florida
Conditions: Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
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Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
ALL
Ages:
All
Trial Updated:
07/25/2024
Locations: RANGER: University of Miami, Miami, Florida
Conditions: Peripheral Nerve Injuries
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Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
NCT04278768
Recruiting
This is a multicenter, open-label, Phase 1/2a dose escalation and expansion study of orally administered emavusertib (CA-4948) monotherapy in adult patients with AML or higher- risk Myelodysplastic Syndrome (hrMDS). Patients enrolling in the Phase 1 dose escalation of the study must meet one of the following criteria prior to consenting to the study: * Relapse/refractory (R/R) AML with FMS-like tyrosine kinase-3 (FLT3) mutations who have been previously treated with a FLT3 inhibitor * R/R AML... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndrome
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The International PNH Interest Group PNH Registry
NCT06524726
Recruiting
The aim of this International PNH Interest Group (IPIG) registry is to develop an international database to prospectively collect data on patients with PNH covering clinical outcomes, patient reported outcomes (PROs), and health-resource utilization (HRU) on all enrolled patients, as well as long term safety data.
Gender:
ALL
Ages:
All
Trial Updated:
07/23/2024
Locations: International PNH Interest Group, Altamonte Springs, Florida
Conditions: Paroxysmal Nocturnal Hemoglobinuria
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CBD for Knee Osteoarthritis
NCT06414473
Recruiting
Osteoarthritis is a disease that affects millions of Americans and is the leading cause of persistent pain and physical disability in the older adult population. Many physically active Americans have reported pain-relieving effects of cannabidiol (CBD) that can reduce or eliminate use of nonsteroidal anti-inflammatory drugs (NSAIDs) for activity-related pain with minimal to no side effects. Long-term use of over-the-counter medications, including NSAIDs, can pose a significant health risk, and t... Read More
Gender:
ALL
Ages:
Between 40 years and 75 years
Trial Updated:
07/23/2024
Locations: Sports Medicine Research Laboratory, Gainesville, Florida
Conditions: Osteoarthritis, Knee
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Ethibond Suture vs Vessel Loop as Draining Seton for Complex Anal Fistulas
NCT05933343
Recruiting
Drainage seton is usually placed for long-term control of symptoms, and hence it has to be effective in drainage of infection, durable, and comfortable to the patients. The present study assumes that different seton materials would attain different drainage capacities, variable durability and impact on QoL. Therefore, the study aims to compare two commonly used seton materials; Ethibond suture and vessel loop, in the management of CAF in terms of effectiveness in draining infection, percent of s... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/23/2024
Locations: Cleveland Clinic Florida, Weston, Florida
Conditions: Anal Fistula
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Integrated Navigation Services for Treatment Adherence, Counseling, and Research
NCT04663152
Recruiting
The goal of this research is to determine whether a Community Health Worker (CHW) intervention including a mobile telehealth (M-Health) component can help achieve long term viral suppression among Black people with poorly controlled HIV.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: University of Miami, Miami, Florida
Conditions: HIV Infection Primary
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