Florida is currently home to 3831 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Innate Immunity in Allergic Asthma
Recruiting
The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Asthma
Tumor-Derived FGF19
Recruiting
Identify and test thresholds, specificity and sensitivity for a potential cancer associated biomarker protein, FGF19, (and associated markers) for detection in human blood in the blood of breast and colorectal in cancer patients, and see if occurs at higher rates than healthy controls
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Burnett School Biomedical Sciences, Orlando, Florida
Conditions: Colorectal Cancer, Breast Cancer, Healthy
4D-150 in Patients With Diabetic Macular Edema
Recruiting
Phase 2 randomized, active-controlled, double-masked, dose-ranging trial in adults with Diabetic Macular Edema (DME).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: National Ophthalmic Research Institute, Fort Myers, Florida
Conditions: Diabetic Macular Edema, Diabetic Retinopathy
Training Response Artificial Intelligence Network (TRAIN)
Recruiting
This study will train a machine learning tool to predict response to a cognitive training intervention using baseline brain MRI sequences from older adults with amnestic mild cognitive impairment.
Gender:
ALL
Ages:
Between 55 years and 100 years
Trial Updated:
12/03/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Amnestic Mild Cognitive Impairment
A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer
Recruiting
This is a first-in-human (FIH), Phase 1/2a, multi center, open-label, single treatment, dose escalation and expansion study designed to determine the safety and tolerability of STM-416 in patients with bladder cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Non-muscle-invasive Bladder Cancer
Paired tVNS With ERP in OCD
Recruiting
In the proposed investigation, the investigator will develop pilot data for the use of tVNS (transcutaneous vagal nerve stimulation) to enhance efficacy of exposure and response prevention therapy (ERP) to improve treatment success in patients with OCD. This data will include tolerability information from therapists and patients with OCD, effect sizes on real world clinical outcomes for the combinatory treatment, and mechanistic data on brain changes associated with treatment.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
12/03/2024
Locations: University of Florida, Gainesville, Florida
Conditions: OCD
Crowdsourcing an Open COVID-19 Imaging Repository for AI Research
Recruiting
The objectives of this project are to (1) assemble a crowdsourced, de-identified radiographic repository; and (2) train and validate existing COVID-NET deep learning diagnostic models.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: COVID-19
Role of Gut Microbiome in Cancer Therapy
Recruiting
This study examines how gut microbiome can affect cancer therapy in cancer patients undergoing cancer therapy or stem cell transplant. The human microbiome affects the way some cancer drugs are metabolized in the human body. Information from this study may help doctors improve the way cancer treatment is delivered, and increase its effectiveness and success.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
12/03/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
The Lake Nona Life Project
Recruiting
The Lake Nona Life Project aims to examine the health and wellness of participants over the course of multiple years, focusing on the links between health and wellness, longevity, quality of life, and human performance.
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
12/03/2024
Locations: Lake Nona Institute, Orlando, Florida
Conditions: Health Behavior, Quality of Life, Aging
Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
Recruiting
BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Parkinson Disease
Finishing HIV Project
Recruiting
This study aims to learn how to help enable healthy behaviors and lower the risk of HIV among Latinx Men.
Gender:
MALE
Ages:
Between 18 years and 54 years
Trial Updated:
12/02/2024
Locations: University of Miami, Miami, Florida
Conditions: Hiv
Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC
Recruiting
The purpose of this study is to identify the recommended dose of vudalimab to be used in combination with chemotherapy (Part 1) and to evaluate the efficacy and safety of vudalimab plus standard of care chemotherapy relative to pembrolizumab plus chemotherapy (Part 2) as first-line treatment in patients with nonsquamous non-small cell lung cancer (NSCLC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: Mid Florida Hematology and Oncology Center, Orange City, Florida
Conditions: Nonsquamous Non-small Cell Lung Cancer