Florida is currently home to 3776 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
Recruiting
This study is a double-blind, randomized controlled trial comparing the effectiveness of oral acetaminophen, diclofenac, and tramadol in reducing the consumption of narcotic doses (primary outcome) and minimizing patients' exposure to narcotics (secondary outcome) following an ultrasound-guided percutaneous needle tenotomy procedure on the lateral elbow.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/20/2024
Locations: The Cleveland Clinic Florida, Coral Springs, Florida
Conditions: Elbow Pain, Chronic Pain
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: South Lake Pain Institute, Clermont, Florida
Conditions: Painful Diabetic Neuropathy
CHOICES3: Sickle Cell Disease Parenting CHOICES
Recruiting
The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/20/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Sickle Cell Disease, Sickle Cell Trait
Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma
Recruiting
The purpose of this research is to find hidden cancer with an experimental magnetic resonance imaging (MRI) scan called spectroscopic magnetic resonance imaging (sMRI). That spectroscopic MRI scan will be used to increase the area of the brain receiving radiation and then the dose of radiation in attempt to kill more of the cancer. Proton radiotherapy and bevacizumab (Avastin) are used to minimize the possible side effects of this approach.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: University of Miami, Miami, Florida
Conditions: Recurrent Glioblastoma
Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma
Recruiting
The purpose of this research is to see if Loncastuximab Tesirine in combination with Rituximab will result in higher complete response rate when given to treat follicular lymphoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Florida Cancer Specialists and Research Institute, Fort Myers, Florida
Conditions: Follicular Lymphoma
Trial to Assess Chelation Therapy in Critical Limb Ischemia
Recruiting
TACT3a is a double blind, placebo-controlled, randomized trial to test a novel therapy, edetate disodium-based chelation of environmentally acquired toxic metals, to reduce cardiovascular events including amputation in high-risk diabetic patients.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/20/2024
Locations: Mount Sinai Medical Center, Miami Beach, Florida
Conditions: Critical Limb Ischemia, Diabetes
Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia
Recruiting
Hypoxic-Ischemic Encephalopathy (HIE) occurs in 20 per 1000 births. Only 47% of neonates treated with the state of the art therapy (induced systemic hypothermia) have normal outcomes. Therefore, other promising therapies that potentially work in synergy with hypothermia to improve neurologic outcomes need to be tested. One potential agent is melatonin. Melatonin is a naturally occurring substance produced mainly from the pineal gland. Melatonin is widely known for its role in regulating the circ... Read More
Gender:
ALL
Ages:
6 hours and below
Trial Updated:
08/20/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Hypoxic Ischemic Encephalopathy
Geolocation Positional System (GPS) Experience
Recruiting
The purpose of this study is to use smartphone technology to capture individual location emotional and cognitive data, to examine how real-world behaviors thoughts, emotions, and brain activity are related to one another.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
08/19/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Emotions, Anhedonia, Depression
Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes
Recruiting
The brief purpose of this research study is to learn about the safety and efficacy of intra-arterial administration of CELZ-201 in patients with newly diagnosed Type 1 Diabetes Mellitus (T1D).
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
08/19/2024
Locations: Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, Florida
Conditions: Type 1 Diabetes, Diabetes Mellitus, Type 1
Rh-PDGF vs EMD for Treatment of Intra-bony Defects
Recruiting
Treatment of intra-bony defects is challenging and requires extensive knowledge of the etiology, anatomy, occlusion, and available biomaterials that can be used to treat this kind of defects. Patients who received scaling and root planing at the college of dental medicine due to periodontal disease, will be screened for inclusion. Only subjects who showed persistent deep probing depth associated with an intrabony defect will be included and will be randomly allocated to one of two treatment grou... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Nova Southeastern University, Davie, Florida
Conditions: Intrabony Periodontal Defect
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
Recruiting
This study will determine whether the presence of DNA repair deficiency in the form of alterations in the genes ATM, CDK12 or CHEK2 predicts for a high likelihood of responding to the use of intermittent high dose testosterone. This therapy may result in responses in tumors which are genetically unstable because of DNA repair deficiency and this is a prospective study to test that hypothesis
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida
Conditions: Metastatic Prostate Cancer
HEMOTAGĀ® Assessment for Short-term Outcomes of Heart Failure
Recruiting
Evaluation of the HEMOTAGĀ® system in a less controlled environment and concurrently develop the system for use by patients with heart failure.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
08/19/2024
Locations: Cleveland Clinic Florida, Weston, Florida
Conditions: Heart Failure (HF)