Florida Clinical Trials

A listing of Florida clinical trials actively recruiting patient volunteers.

The main purpose of a clinical trial or research study is to test how effective and safe a new experimental treatment or intervention is in humans before it is released to the public. A clinical trial usually tests treatments such as medications, screening tests, alternative medicines such as herbs, and medical devices like prosthesis and pacemakers. There are a wide array of clinical research study centers in Florida that provide both paid and non-paid clinical trials.

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3888 trials found

A Proof-of-Concept Study Evaluating LINFU™

NCT05161013

The purpose of this research study is to study a method to detect pancreatic precancer and cancer (ductal adenocarcinoma) using ultrasound technology in those who are at significantly increased risk for developing pancreatic cancer. The LINFU™ Technique is done by analysis of pancreatic fluid collected with the help of ultrasound. This is an investigational way to detect pancreatic precancers and ductal adenocarcinoma.

Conditions: Pancreas Adenocarcinoma, Dysplasia
Phase: Not Applicable

A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 18- to 30-Year-Old Healthy Adults

NCT05164094

The main objective of this trial is to evaluate the safety and reactogenicity of mRNA-1189 in 18- to 30-year-old healthy adults.

Conditions: Epstein-Barr Virus Infection

Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles

NCT05163353

Trial to confirm the effectiveness and demonstrate the safety of treatment with diluted Radiesse for correction of Décolleté Wrinkles.

Conditions: Décolleté Wrinkles
Phase: Not Applicable

Phase 4 COPD and Suboptimal Inspiratory Flow Rate

NCT05165485

Study is a randomized, double-blind, double-dummy, parallel-group study evaluating efficacy and safety of revefenacin vs. tiotropium in adults with severe to very severe COPD and suboptimal PIFR.

Conditions: Chronic Obstructive Pulmonary Disease

Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure

NCT05165290

Prospective, double-masked, randomized, multi-center, active-controlled, parallel-group, 3-month study assessing the safety and ocular hypotensive efficacy of TearClear latanoprost Ophthalmic Solution, 0.005% (TC-002) compared to latanoprost Ophthalmic Solution, 0.005% (LAT) in subjects with elevated intraocular pressure at approximately 20 study sites located in the United States

Conditions: Elevated Intraocular Pressure

Efficacy and Safety of Tozorakimab (MEDI3506) in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations.

NCT05166889

The purpose of this Phase III study is to evaluate the efficacy and safety of Tozorakimab (MEDI3506) Dose 1 and Dose 2 administered subcutaneously (SC) in adult participants with symptomatic COPD and history of ≥ 2 moderate or ≥ 1 severe exacerbation of COPD in the previous 12 months. Participants should be receiving optimised treatment with maintenance inhaled therapy (ICS/LABA/LAMA triple therapy, or dual therapy if triple is not indicated or contraindicated) at a stable dose for at least 3 mo ...

Conditions: Chronic Obstructive Pulmonary Disease (COPD)

Study to Evaluate Pharmacokinetic Comparability Between AZD7442 Co-formulation (AZD8895 + AZD1061) vs AZD8895 and AZD1061 Individually in Adult Healthy Participants

NCT05166421

The study will assess pharmacokinetic (PK) comparability between different formulations of AZD7442, which is a combination of two individual monoclonal antibodies (mAbs), AZD8895 and AZD1061.

Conditions: Corona Virus Disease

Evaluation of a Self-Monitoring Intervention to Reduce Safety Behavior in Social Anxiety

NCT05168020

The current study aims to explore the efficacy of a text message based Safety Behavior Fading Intervention compared to a control intervention.

Conditions: Social Anxiety
Phase: Not Applicable

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058

NCT05169580

This is a study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of FTX-6058 in subjects with sickle cell disease.

Conditions: Sickle Cell Disease, Sickle Cell Anemia

Evaluate the Effectiveness and Safety of the Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health.

NCT05170113

The purpose of this study is to assess the effectiveness and safety of the Alpinia galanga formulation, Theacrine formulation, and Caffeine formulation on fatigue, mental acuity, and cognitive health among overall healthy participants

Conditions: Fatigue
Phase: Not Applicable

Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma

NCT05170334

This research study is investigating Binimetinib and Belinostat in participants with metastatic uveal melanoma. The research study will test the study drugs to see if the combination of binimetinib and belinostat can make tumors shrink or stop growing.

Conditions: Metastatic Uveal Melanoma

Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

NCT05172726

This is an open-label, multi-center, Phase 3 study to evaluate tapinarof cream, 1% in pediatric subjects with plaque psoriasis.

Conditions: Plaque Psoriasis

Clinical trials have several phases, and each phase has a different goal. The first phases aim to measure the toxicity of a drug to learn what would be the correct dosage for a patient. During the first phases investigators also pay close attention to any side effects or potential dangers to consider before releasing the drug.

During the last few phases of clinical research studies, investigators test the intervention on larger and more inclusive groups of individuals to continue examining the effectiveness and side effects of the medication. If individual decides to enroll in a clinical trial the research team usually discloses what phase he/she is joining beforehand, however all phases usually have the same potential benefits and/or side effects.

In Florida, there are some large universities that conduct clinical trials and other types of research studies about different categories both for healthy and non-healthy volunteers. Universities often partner with local hospitals and doctors to conduct research studies. The University of Miami research division in Miami, Florida often partners with Jackson Health Systems. Together, they conduct the largest amount of clinical trials in South Florida with over 700 ongoing trials as of this month.

The University of Florida, located in Gainesville, Florida has conducted more than 4,000 research studies over the past four years and actively searches for both non-paid and paid volunteers to participate in clinical trials. You can also find clinical trials in local hospitals such as the Baptist Hospital, the Cleveland Clinic, and the Mayo Clinic. The following lists clinical trials located in Florida that have been provided by clinicaltrials.gov.

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