Florida Clinical Trials

A listing of Florida clinical trials actively recruiting patient volunteers.

The main purpose of a clinical trial or research study is to test how effective and safe a new experimental treatment or intervention is in humans before it is released to the public. A clinical trial usually tests treatments such as medications, screening tests, alternative medicines such as herbs, and medical devices like prosthesis and pacemakers. There are a wide array of clinical research study centers in Florida that provide both paid and non-paid clinical trials.

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3726 trials found

Biomarkers in Aortic Stenosis - B.A.S.S.


This study is being done to determine whether or not new blood test(s) can determine the severity of heart conditions. Aortic stenosis, hypertrophic cardiomyopathy, mitral regurgitation, aortic regurgitation, artificial heart valve regurgitation or stenosis, and tricuspid valve regurgitation associated with pacemaker leads are the cardiac disorders under study. The blood tests involve analysis for von Willebrand Factor antigen and activity, von Willebrand Factor multimers, and brain natriuretic ...

Conditions: Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency

S0820, Adenoma and Second Primary Prevention Trial


The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon or rectal cancer.

Conditions: Colorectal Neoplasms

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)


This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications.

Conditions: Hematologic Malignancies, Inherited Disorders of Metabolism, Inherited Abnormalities of Platelets, Histiocytic Disorders, Acute Myelogenous Leukemia (AML or ANLL), Acute Lymphoblastic Leukemia (ALL), Other Acute Leukemia, Chronic Myelogenous Leukemia (CML), Myelodysplastic (MDS) / Myeloproliferative (MPN) Diseases, Other Leukemia, Hodgkin Lymphoma, Non-hodgkin Lymphoma, Multiple Myeloma/ Plasma Cell Disorder (PCD), Inherited Abnormalities of Erythrocyte Differentiation or Function, Disorders of the Immune System, Severe Aplastic Anemia, Autoimmune Diseases

An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis


The purpose of this study is to examine the long-term safety of Abatacept for the treatment of juvenile idiopathic arthritis (JIA) with particular in interest in the occurrence of serious infections, autoimmune disorders, and malignancies.

Conditions: Juvenile Idiopathic Arthritis

MRI-Mapped Dose-Escalated Salvage Radiotherapy Post-Prostatectomy: The MAPS Trial


The investigators hypothesize that increasing radiation dose to the functional MRI-defined lesion in the prostate bed will result in an improved initial complete response (reduction in prostate-specific antigen (PSA) to < 0.1 ng/mL), which is related to long-term outcome biochemically. Biomarker expression levels differ in the DCE-MRI enhancing and non-enhancing tumor regions (when applicable). 10-15% of men undergoing RT have free circulating DNA (fcDNA) or tumor cells (CTC) that are related to ...

Conditions: Prostate Cancer, Prostate Adenocarcinoma
Phase: Phase 2/3

Ixazomib in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib


This randomized phase II trial studies how well ixazomib (ixazomib citrate) works in treating patients with multiple myeloma that has returned after a period of improvement but is not resistant to bortezomib. Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma

Brain and Abdominal Aneurysm Study


Aneurysmal subarachnoid hemorrhage (aSAH) is the most deadly kind of stroke. Each year, 40,000 Americans have SAH. Case-fatality approaches 60% and more than half of those who die do so before reaching the hospital. Most commonly, SAH results from rupture of an intracranial aneurysm. Screening high-risk individuals could identify those at greatest risk and decrease the devastating effect of SAH. Aortic Aneurysm also constitutes a major public health problem with high lethality. Current estimates ...

Conditions: Aneurysm

Phase 3 Study of ProstAtak® Immunotherapy With Standard Radiation Therapy for Localized Prostate Cancer


The purpose of this study is to evaluate the effectiveness of ProstAtak® immunotherapy in combination with radiation therapy for patients with intermediate-high risk localized prostate cancer. ProstAtak kills tumor cells and stimulates a cancer vaccine effect. Killing tumor cells in an immune stimulatory environment induces the body's immune system to detect and destroy cancer cells. ProstAtak has shown synergy with radiation without added toxicity and lower than expected recurrence rates in pre ...

Conditions: Prostate Cancer

Male Fertility Program


Following spinal cord injury, most men are infertile and require medical assistance to father children. The conditions that contribute to their infertility are erectile dysfunction, ejaculatory dysfunction, and semen abnormalities. The Miami Project Male Fertility Program is a research study designed to understand and improve impairments to male fertility resulting from spinal cord injury.

Conditions: Spinal Cord Injury

HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network


The primary purpose of the HCV-TARGET study is to establish a nationwide registry of patients undergoing treatment with antiviral therapies for chronic hepatitis C (HCV) at both academic and community practices.

Conditions: Hepatitis C

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy


The purpose of this research study is to determine the potential of magnetic resonance imaging, spectroscopy, and whole body imaging to monitor disease progression and to serve as an objective outcome measure for clinical trials in Muscular Dystrophy (MD). The investigators set forth to learn more about the changes that occur in muscles of the lower extremity and arm muscles. The investigators will compare the muscles of ambulatory or non-ambulatory boys with DMD with muscles of healthy childre ...

Conditions: Duchenne Muscular Dystrophy, Becker Muscular Dystrophy

Long-Term Safety Study Of Tofacitinib In Patients With Juvenile Idiopathic Arthritis


Evaluate long-term safety and tolerability of tofacitinib in patients with JIA, who have previously participated in tofacitinib JIA studies.

Conditions: Juvenile Idiopathic Arthritis

Clinical trials have several phases, and each phase has a different goal. The first phases aim to measure the toxicity of a drug to learn what would be the correct dosage for a patient. During the first phases investigators also pay close attention to any side effects or potential dangers to consider before releasing the drug.

During the last few phases of clinical research studies, investigators test the intervention on larger and more inclusive groups of individuals to continue examining the effectiveness and side effects of the medication. If individual decides to enroll in a clinical trial the research team usually discloses what phase he/she is joining beforehand, however all phases usually have the same potential benefits and/or side effects.

In Florida, there are some large universities that conduct clinical trials and other types of research studies about different categories both for healthy and non-healthy volunteers. Universities often partner with local hospitals and doctors to conduct research studies. The University of Miami research division in Miami, Florida often partners with Jackson Health Systems. Together, they conduct the largest amount of clinical trials in South Florida with over 700 ongoing trials as of this month.

The University of Florida, located in Gainesville, Florida has conducted more than 4,000 research studies over the past four years and actively searches for both non-paid and paid volunteers to participate in clinical trials. You can also find clinical trials in local hospitals such as the Baptist Hospital, the Cleveland Clinic, and the Mayo Clinic. The following lists clinical trials located in Florida that have been provided by clinicaltrials.gov.

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