Maryland is currently home to 2872 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Human Behaviors Related to the Expectation of Pain
Recruiting
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear. We will develop and use novel objective methods for measurement of expectation and threat related attention. The results of this study may lead to testable hypotheses regarding the psychological basis of the fear of pain, threat and task related attention. We will also use... Read More
Gender:
All
Ages:
Between 16 years and 88 years
Trial Updated:
05/12/2023
Locations: Hopkins Epilepsy Monitoring Unit, Zayhed 12., Baltimore, Maryland
Conditions: Fear Pain
StableEyes With Active Neurofeedback
Recruiting
The investigators have developed a self-administered rehabilitation tool that incrementally guides the user to increase head motion to mitigate motion sickness and enhance postural recovery following centrifugation or unilateral vestibular nerve deafferentation surgery.
Gender:
All
Ages:
Between 21 years and 70 years
Trial Updated:
05/11/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Vestibular Disorder, Vestibular Schwannoma, Space Motion Sickness, Motion Sickness
ROSE-Longitudinal Assessment With Neuroimaging
Recruiting
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Intracerebral Hemorrhage
Risk Indicators of Sarcoidosis Evolution-Unified Protocol
Recruiting
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
Gender:
All
Ages:
19 years and above
Trial Updated:
05/10/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Sarcoidosis, Pulmonary
The Use of "Smart" Body-Weight Scales for Weight and Nutritional Monitoring in Patients With Head and Neck Cancer Undergoing Radiation Therapy
Recruiting
This clinical trial studies the use of "smart" body-weight scales to monitor weight and nutrition among patients with head and neck cancer undergoing radiation therapy. Malnutrition affects 30-50% of patients diagnosed with head and neck cancer, and approximately 30% of patients have malnutrition prior to diagnosis. "Smart" body weight scales can possibly make self-weighing easier, faster, and more accurate through weight recordings through mobile applications available for "smart" scales. This... Read More
Gender:
All
Ages:
All
Trial Updated:
05/10/2023
Locations: Mid-Atlantic Permanente Medical Group, Rockville, Maryland
Conditions: Head and Neck Squamous Cell Carcinoma, Malignant Head and Neck Neoplasm
The Oxford Risk Factors And Non-Invasive Imaging Study
Recruiting
ORFAN is a prospective, multi-centre, multi-ethnic cohort observational study collecting CT scans, biological material and outcomes data, to develop and validate novel biomarkers of cardiometabolic and other disease risk.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/09/2023
Locations: NIH National Heart, Lunch, and Blood Institute, Bethesda, Maryland
Conditions: Cardiovascular Diseases, Cardiovascular Risk Factors
Speech Perception and High Cognitive Demand
Recruiting
With advancing age, adults experience increasing speech understanding difficulties in challenging situations. Currently, speech-in-noise difficulties are rehabilitated by providing hearing aids. For older normal-hearing adults, however, hearing devices do not provide much benefit since these adults do not have decreased hearing sensitivity. The goal of the "Speech Perception and High Cognitive Demand" project is to evaluate the benefit of a new auditory-cognitive training paradigm. In the presen... Read More
Gender:
All
Ages:
Between 65 years and 85 years
Trial Updated:
05/09/2023
Locations: Department of Hearing and Speech Sciences, College Park, Maryland
Conditions: Speech Intelligibility, Aging
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
05/09/2023
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV
Recruiting
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated with fat accumulation that ranges from benign, non-progressive liver fat accumulation to severe liver injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in US adults and the second leading cause for liver transplantation in the US. The natural history of NAFLD in the general population has been well described, with those with non-alcoholic fatty liver (NAFL, or simple steatosis) destin... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/08/2023
Locations: John Hopkins University, Baltimore, Maryland
Conditions: NAFLD, NAFLD-HIV, Hiv
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Recruiting
Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due to problems with attention and high levels of impulsivity and hyperactivity. They are at substantially increased risk for long-term difficulties into adulthood, including academic underachievement, substance abuse, and criminal behavior. The diagnosis of ADHD, which is based on subjective ratings by parents and teachers, likely results fr... Read More
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
05/08/2023
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Attention Deficit Hyperactivity Disorder Combined
HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients
Recruiting
The primary objective of this study is to determine if an HIV-infected donor liver (HIVD+) transplant is safe with regards to major transplant-related and HIV-related complications
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Maryland, Institute of Human Virology, Baltimore, Maryland
Conditions: Hiv
Human Upper Extremity Allotransplantation: F/U Protocol
Recruiting
Upper extremity allotransplantation is a new procedure which is becoming more common in the United States. Ongoing data collection for research purposes is vital to the long-term assessment as to the safety of the procedure and accompanying immunosuppression protocol, as well as quantifying patient outcomes and changes in quality of life. For these reasons, The Johns Hopkins Hand/Arm Transplantation Team is interested in enrolling transplanted patients in a follow-up protocol to continue collect... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/05/2023
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Amputation, Traumatic, Wounds and Injury, Hand Injuries