New York is currently home to 4500 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Innate Immunity Stimulation Via TLR9 in Early AD
Recruiting
This single-center, double-blind, placebo-controlled study will recruit in total 39 participants with either Mild Cognitive Impairment due to Alzheimer's disease (MCI) or Mild Alzheimer's disease dementia (mild AD). There will be 3 Dose levels. An initial cohort of 13 subjects will be randomized to a Dose level 1 (0.1 mg/kg vs. placebo) lasting 8 weeks. An additional 13 subjects will be recruited and randomized into Dose level 2 (0.25 mg/kg vs. placebo) for 8 weeks and 13 subjects for the last D... Read More
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
02/25/2025
Locations: NYU Langone Health, New York, New York
Conditions: Mild Cognitive Impairment, Alzheimer Dementia
First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors
Recruiting
This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1305/BNT325 in subjects with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Site 102, New York, New York
Conditions: Advanced Solid Tumor
A Study of NB003 in Patients with Advanced Malignancies
Recruiting
This a A Phase 1, Open-label, Multicenter Study to Assess the Safety, Tolerability, and Pharmacokinetics of NB003 in Subjects with Advanced Malignancies
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Memorial Sloan Kettering Cancer Center, Long Island, New York
Conditions: Advanced Solid Tumor
A Multi-Phase Study Examining Hospital to Home Transitions for Children With Medical Complexity
Recruiting
The overarching objective of this study is to make it easier for parents of children with medical complexity (CMC) to take care of their children after discharge home from the hospital and reduce the chance of post-hospitalization morbidity (meaning bad outcomes such as readmissions) after discharge. CMC, or those with multiple chronic conditions, progressive conditions, or technology dependence, are at high risk for post-hospitalization morbidity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: NYU Langone Health, New York, New York
Conditions: Children With Medical Complexity (CMC)
Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer
Recruiting
This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.
Gender:
MALE
Ages:
Between 21 years and 90 years
Trial Updated:
02/25/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Prostate Cancer
Amplatzer Amulet LAAO Vs. NOAC
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: South Shore University Hospital-Northwell, Bay Shore, New York
Conditions: Atrial Fibrillation, Stroke, Bleeding
Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Recruiting
The purpose of this study is to follow participants with Cushing's syndrome during the course of their routine care and to form a data registry to study long term participant outcomes.
Gender:
ALL
Ages:
14 years and above
Trial Updated:
02/25/2025
Locations: Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activity), Commack, New York
Conditions: Cushing's Disease, Cushing Syndrome, Cushing Disease
Vitamin D Dynamics in Women
Recruiting
The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D... Read More
Gender:
FEMALE
Ages:
Between 20 years and 39 years
Trial Updated:
02/25/2025
Locations: University of Rochester, 518 Hylan Building, Rochester, New York
Conditions: Pregnancy
Pediatric Down Syndrome Post-Approval Study
Recruiting
The purpose of this Post Approval research study is to assess ongoing safety and effectiveness of the Inspire therapy in adolescents and young adults (age 13-18) with Down syndrome and severe sleep apnea. The objective of the study is to provide an ongoing safety and effectiveness assessment of the Inspire UAS System in the Pediatric Down syndrome population.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
02/24/2025
Locations: Northwell Cohen Children's Hospital, Queens, New York
Conditions: Pediatric Obstructive Sleep Apnea, Down Syndrome (DS)
Establishment of ProNephro AKI (NGAL) Cut Off Value for Risk Assessment of Moderate to Severe Acute Kidney Injury in Adults
Recruiting
The purpose of this research is to collect blood and urine from adult patients admitted to an intensive care unit. This is to assess the performance of the ProNephro AKI (NGAL) assay (lab test) as an aid to identify patients at risk for acute kidney injury.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
02/24/2025
Locations: Columbia University, New York, New York
Conditions: Acute Kidney Injury
Impact of Bright Light Therapy on Prader-Willi Syndrome
Recruiting
This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with Prader-Willi Syndrome
Gender:
ALL
Ages:
Between 6 years and 88 years
Trial Updated:
02/24/2025
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Prader-Willi Syndrome, Excessive Daytime Sleepiness, Hyperphagia, Body Weight, Mood, Behavior
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Recruiting
A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions undergoing PCI will be randomized into two groups: treatment with the MagicTouch™ sirolimus-coated balloon or POBA on a 2:1 basis. Approximately 492 subjects will be enrolled in the randomized study in a... Read More
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
02/24/2025
Locations: Montefiore Medical Center - Moses Division, Bronx, New York
Conditions: In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease