New York is currently home to 4439 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Intrathecal Dexmedetomidine Vs Epinephrine
Recruiting
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-infer... Read More
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
10/09/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Cesarean Section, Anesthesia, Spinal
Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People with Sarcoma
Recruiting
The purpose of this study is to investigate the feasibility of early access to mental healthcare during sarcoma treatment as well as to assess the association between early access to psychiatric care and depression, anxiety, postoperative outcomes, and patient satisfaction in patients undergoing surgery for musculoskeletal sarcoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities ), Commack, New York
Conditions: Sarcoma, Bone Sarcoma, Soft Tissue Sarcoma
A Digitally Assisted Risk Reduction Platform for Youth At High Risk for Suicide
Recruiting
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be used to provide a unique understanding of risk factors, including psychological distress, anhedonia and behavioral withdrawal, and sleep disturbance among high-risk individuals. This project aims to enhance the effectiveness of the delivery of preventative health care to yo... Read More
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
10/09/2024
Locations: Columbia University, New York, New York
Conditions: Suicide, Mental Health Disorder, Anhedonia
How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD
Recruiting
Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the fear extinction network and on their OCD symptoms.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
10/09/2024
Locations: New York State Psychiatric Institute, New York, New York
Conditions: OCD
Iberdomide Maintenance Therapy in Patients With Multiple Myeloma
Recruiting
This study will determine the feasibility, safety and efficacy of iberdomide maintenance therapy post-autologous stem cell transplant (ASCT). Treatment will continue until disease progression or toxicity. The results from this study will inform the feasibility of pursuing a study comparing iberdomide to lenalidomide maintenance post-ASCT.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Multiple Myeloma
Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
Recruiting
The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.
Gender:
ALL
Ages:
Between 3 months and 18 years
Trial Updated:
10/09/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: Pediatric Pulmonary Hypertension
Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy
Recruiting
The OPTIMIZER Smart Post-Approval Study is a prospective, multi-center, non-randomized, single arm open label study of 620 subjects receiving an OPTIMIZER implant as standard of care. Patients to be included will have NYHA functional class III symptoms and a left ventricular ejection fraction of 25-45%
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: Mount Sinai Morningside, New York, New York
Conditions: Heart Failure
Monitoring Minimal Residual Disease of Patients with Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome
Recruiting
This study is being performed to develop assays to determine the impact of the therapy patients receive for treatment of AML or MDS and to determine if these tests can identify those patients who are at a greater risk for having their disease relapse.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management
Recruiting
The Icahn School of Medicine at Mount Sinai will conduct a randomized controlled trial of a self-management support intervention for predominantly minoritized and low-income adults with chronic obstructive pulmonary disease (COPD). The trial will focus on comprehensive screening and targeted management of barriers to COPD control, incorporating home-based pulmonary rehabilitation and oral steroid and antibiotic prescribing for pre-emptive treatment of COPD exacerbations. The research team will c... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/08/2024
Locations: Ichan School of Medicine at Mount Sinai, New York, New York
Conditions: Chronic Obstructive Pulmonary Disease
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Amyotrophic Lateral Sclerosis
RELAXaHEAD for Headache Patients (Phase III)
Recruiting
This study is a fully powered, remote randomized control trial to evaluate RELAXaHEAD in people with migraine.
Gender:
ALL
Ages:
Between 16 years and 80 years
Trial Updated:
10/08/2024
Locations: NYU Langone Health, New York, New York
Conditions: Migraine
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Recruiting
Primary objective: To identify older adults with transthyretin cardiac amyloidosis (ATTR-CA) early in the course of the illness, at a time when disease modifying therapies are most effective. The specific aims of this epidemiologic investigation include: 1. To identify subjects with previous lumbar spinal stenosis (LSS) Surgery who have evidence of transthyretin (TTR) amyloid deposits in spinal specimens and could be at risk for ATTR cardiac amyloidosis. 2. To evaluate for ATTR-CA among those... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
10/08/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Lumbar Spinal Stenosis, Cardiac Amyloidosis, ATTR Amyloidosis Wild Type, ATTR Gene Mutation, ATTRV122I Amyloidosis, Cardiomyopathy, Hypertrophic