New York is currently home to 4470 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
Recruiting
This is a pragmatic phase III, randomized, blinded, double placebo-controlled, three-arm trial of elderly patients following cardiac surgery to assess the relationship between nighttime intravenous (IV) and sublingual dexmedetomidine on postoperative delirium and functional outcomes after surgery.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/06/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Delirium
Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers
Recruiting
The purpose of this study is to develop and test a new communication training intervention called Hematolo-GIST to help oncologists communicate with patients about their lymphoma diagnosis and advance care planning.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Memorial Sloan Kettering Cancer Center (All protocol activities), New York, New York
Conditions: Lymphoma, B-Cell, Lymphoma, Large-cell Lymphoma, Large B-cell Lymphoma, DLBCL - Diffuse Large B Cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell Lymphoma
Glycemic Effect of Diazoxide in NAFLD
Recruiting
The goal of this clinical trial is to compare a two-week course of diazoxide (at two different doses) and placebo in people with overweight/obesity and insulin resistance (IR) with, or at high risk for, non-alcoholic fatty liver disease (NAFLD). The main questions it aims to answer are how mitigation of compensatory hyperinsulinemia with diazoxide affects parameters of glucose and lipid metabolism (how people with IR and NAFLD respond to lowering high insulin levels so that the investigators can... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/06/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State
Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients
Recruiting
The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT). Primary Objective To determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors. Secondary Objectives: * To develop and validate a classifier based on pre-transplant immunological profi... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
01/06/2025
Locations: The Children's Hospital at Montefiore, Bronx, New York
Conditions: Hematopoietic Cell Transplant, Solid Organ Transplant, Respiratory Viral Infection
Survey on Lymphedema After Sentinel Lymph Node Biopsy in People With Cervical or Vulvar Cancer
Recruiting
The purpose of this study is to collect information that may identify people who are at risk of developing lower extremity lymphedema (LEL) after sentinel lymph node biopsy (SLN) during surgery for early-stage vulvar or cervical cancer, and to improve the quality and accuracy of the information that is given to people who have this procedure. Please note that, during this study, the researchers will collect information from a questionnaire completed by people who had SLN and LND+/- SLN during s... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Cervical Cancer, Vulvar Cancer
The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease
Recruiting
The aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/06/2025
Locations: Mount Sinai Hospital, New York, New York
Conditions: Coronary Artery Disease
Hearing Impairment, Strategies and Outcomes in VA Emergency Departments
Recruiting
HearVA involves six VA facility emergency departments (ED) over a 3-year intervention period. The first part of this study will test whether providing personal amplifiers to Veteran ED patients who self-report hearing difficulty is acceptable to these patients, can improve their hearing, enhance understanding of discharge instructions, and can reduce the risk of coming back to the ED in a short period of time (3 days and 30 days). The second part of the study will then identify whether ED staff... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/06/2025
Locations: James J. Peters VA Medical Center, Bronx, NY, Bronx, New York
Conditions: Hearing Loss, Emergency Service, Hospital Readmission
Autus Valve Pivotal Study
Recruiting
Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 months to 16 years requiring surgical pulmonary valve replacement. The Autus Valve may be expanded pre-implant to match the subject's body size. Subjects will be evaluated prior to the Autus Valve implant procedure, immediately post-implant, at hospital discharge, 30 days, 6 months, and annually through 10 years. The Autus Valve may be expanded post-i... Read More
Gender:
ALL
Ages:
Between 18 months and 16 years
Trial Updated:
01/06/2025
Locations: Columbia University Irving Medical Center/New York Presbyterian Morgan Stanley Children's Hospital, New York, New York
Conditions: Congenital Heart Disease
MISP 60528 Pneumococcal Vaccination
Recruiting
This study aims to use two different blood tests (ELISA and OPA) to study response to pneumococcal vaccination administered as per standard guidelines in patients who are undergoing workup for heart transplant (whether or not they have undergone LVAD implantation or have undergone heart transplant.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Montefiore Medical Center, Infectious Diseases, Bronx, New York
Conditions: Heart Transplant Infection Prevention
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
Recruiting
A prospective, single-arm, multi-center post-market surveillance study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Patients Requiring Dialysis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Albany Medical Center, Albany, New York
Conditions: Kidney Disease, End-Stage, End-stage Renal Disease, Arteriovenous Fistula
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
Recruiting
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investigators use a stimulation method called transcranial direct current stimulation (tDCS). The investigators cover two electrodes in damp sponges, place them on the scalp, and pass a weak electrical current between them. Some of this current passes through the brain and can change brain activity. One elec... Read More
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
01/06/2025
Locations: City University of New York, New York, New York
Conditions: Aphasia, Stroke
A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell Lymphoma
Recruiting
The overarching goals of this study are to measure levels of circulating tumor DNA (ctDNA) in patients with early stage diffuse large B cell lymphoma (DLBCL), to assess the change in ctDNA during treatment in order to prospectively identify markers of treatment failure, and to use ctDNA as a future tool for response adapted therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: University of Rochester, Rochester, New York
Conditions: DLBCL