New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Amplatzer Amulet LAAO Vs. NOAC
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: South Shore University Hospital-Northwell, Bay Shore, New York
Conditions: Atrial Fibrillation, Stroke, Bleeding
Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Recruiting
The purpose of this study is to follow participants with Cushing's syndrome during the course of their routine care and to form a data registry to study long term participant outcomes.
Gender:
ALL
Ages:
14 years and above
Trial Updated:
02/25/2025
Locations: Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activity), Commack, New York
Conditions: Cushing's Disease, Cushing Syndrome, Cushing Disease
Vitamin D Dynamics in Women
Recruiting
The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D... Read More
Gender:
FEMALE
Ages:
Between 20 years and 39 years
Trial Updated:
02/25/2025
Locations: University of Rochester, 518 Hylan Building, Rochester, New York
Conditions: Pregnancy
Pediatric Down Syndrome Post-Approval Study
Recruiting
The purpose of this Post Approval research study is to assess ongoing safety and effectiveness of the Inspire therapy in adolescents and young adults (age 13-18) with Down syndrome and severe sleep apnea. The objective of the study is to provide an ongoing safety and effectiveness assessment of the Inspire UAS System in the Pediatric Down syndrome population.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
02/24/2025
Locations: Northwell Cohen Children's Hospital, Queens, New York
Conditions: Pediatric Obstructive Sleep Apnea, Down Syndrome (DS)
Establishment of ProNephro AKI (NGAL) Cut Off Value for Risk Assessment of Moderate to Severe Acute Kidney Injury in Adults
Recruiting
The purpose of this research is to collect blood and urine from adult patients admitted to an intensive care unit. This is to assess the performance of the ProNephro AKI (NGAL) assay (lab test) as an aid to identify patients at risk for acute kidney injury.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
02/24/2025
Locations: Columbia University, New York, New York
Conditions: Acute Kidney Injury
Impact of Bright Light Therapy on Prader-Willi Syndrome
Recruiting
This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with Prader-Willi Syndrome
Gender:
ALL
Ages:
Between 6 years and 88 years
Trial Updated:
02/24/2025
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Prader-Willi Syndrome, Excessive Daytime Sleepiness, Hyperphagia, Body Weight, Mood, Behavior
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Recruiting
A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions undergoing PCI will be randomized into two groups: treatment with the MagicTouch™ sirolimus-coated balloon or POBA on a 2:1 basis. Approximately 492 subjects will be enrolled in the randomized study in a... Read More
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
02/24/2025
Locations: Montefiore Medical Center - Moses Division, Bronx, New York
Conditions: In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease
Virtual Reality Treadmill Training in Individuals with Traumatic Brain Injury
Recruiting
This pilot study aims to determine the feasibility of a virtual reality treadmill training intervention in individuals with Traumatic Brain Injury (TBI). Participants will be stratified based on age into adults' group or older adults' group and then randomized into the virtual reality treadmill training (intervention) group with feedback or the treadmill training (control) group. This pilot study will also provide preliminary evidence on the impact of the virtual reality treadmill training on mo... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
02/24/2025
Locations: NYU Langone Health, New York, New York
Conditions: Traumatic Brain Injury
Preoperative Oral Hydration in the Ambulatory Arthroplasty Population
Recruiting
The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint arthroplasty.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/24/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Same-day Discharge, Length of Stay
Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder
Recruiting
This study will enroll patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for post-traumatic stress disorder (PTSD). Following an initial screening visit, clinical assessment, and enrollment, subjects will be randomized into treatment and placebo arms. Both cohorts will undergo a pre-intervention functional magnetic resonance imaging (fMRI) of their brain. Treatment subjects will receive unilateral two-level stellate ganglion block via ultrasou... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/24/2025
Locations: NYU Langone Health, New York, New York
Conditions: Post Traumatic Stress Disorder
Axitinib and Nivolumab for the Treatment of Mucosal Melanoma
Recruiting
The researchers are doing this study to find out whether the combination of axitinib and nivolumab is an effective and safe treatment for people with advanced or metastatic mucosal melanoma that has not been treated before. The researchers think that a combination of axitinib and nivolumab may help people with this disease because both drugs target and block proteins that play a role in cancer cell survival and growth. The researchers think the drugs may be more effective if given in combinatio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Memorial Sloan Kettering Westchester, Harrison, New York
Conditions: Mucosal Melanoma
Enfortumab Vedotin and Pembrolizumab in People with Bladder Cancer
Recruiting
This study will test whether enfortumab vedotin combined with pembrolizumab is an effective treatment for people with bladder cancer (urothelial carcinoma) involving the lymph nodes who are going to have surgery to remove their cancer (cystectomy). The researchers will look at whether treatment with enfortumab vedotin and pembrolizumab before surgery can get rid of cancer within the lymph nodes. They will also try to find out if this combination of drugs is effective at shrinking participants' c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Memorial Sloan Kettering -Nassau, Commack, New York
Conditions: Urothelial Carcinoma