New York is currently home to 4500 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma
Recruiting
This Phase 1/ 2a study is a multicenter study to evaluate the safety, tolerability and efficacy of SCG101 in subjects with hepatitis B virus-related hepatocellular carcinoma
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/16/2025
Locations: New York, New York, New York
Conditions: Hepatitis B Virus Related Hepatocellular Carcinoma, Hepatocellular Carcinoma Recurrent
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
Recruiting
This phase II Expanded Lung-MAP treatment trial tests tepotinib with or without ramucirumab for the treatment of patients with advanced non-small cell lung cancer that has spread from where it first started (primary site) to other places in the body (stage IV) or that has come back after a period of improvement (recurrent). Tepotinib is used in patients whose cancer has a mutated (changed) form of a gene called MET. It is in a class of medications called kinase inhibitors. It works by blocking t... Read More
Gender:
ALL
Ages:
All
Trial Updated:
02/14/2025
Locations: Memorial Sloan Kettering Commack, Commack, New York
Conditions: Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
How is Social Connection Represented in the Brain?
Recruiting
Nearly half of the U.S. population sometimes or always experiences loneliness, which is alarming given that loneliness confers risk for negative mental and physical health outcomes. Extensive research suggests loneliness is characterized by subjective isolation: many lonely individuals maintain a number of relationships but still report feeling lonely. The goal of this proposal is to use functional magnetic resonance imaging to reveal how the brain represents our subjective connection to and iso... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/14/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Loneliness
Supportive Care Needs of Caregivers of People With Erdheim-Chester Disease and Other Histiocytic Diseases
Recruiting
This study is being done to answer the following question: What are the supportive care needs of informal caregivers of people with Erdheim-Chester disease and other histiocytic diseases?
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Supportive Care Needs of Caregivers
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
Recruiting
A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Columbia University, New York, New York
Conditions: Obstructive Sleep Apnea of Adult, Preeclampsia, Obstetrical Complications
Physical Activity and Cognitive Development in Children
Recruiting
1. Compare physical activity and cognitive functions between children having cardiac surgery with an age-matched group of children undergoing non-cardiac surgery, as well as otherwise healthy siblings or best buddies (or age and gender-matched children if no siblings or best buddies available) before surgery and after surgery or six months following initial assessment. 2. Determine the effects of a structured physical activity program for 6 months following surgery on cognitive functions and ada... Read More
Gender:
ALL
Ages:
Between 30 months and 6 years
Trial Updated:
02/14/2025
Locations: Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York, New York
Conditions: Congenital Heart Diseases, Children
A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer
Recruiting
This Phase 3, single-arm, multicenter study will evaluate the efficacy and safety of UGN-103, a novel formulation of UGN-102, instilled in the urinary bladder of patients with low-grade non-muscle invasive bladder cancer (LG-NMIBC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: Great Lakes Physician dba WNYU, Cheektowaga, New York
Conditions: Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
Study to Evaluate the Safety and Efficacy of Bicalutamide in Combination with Sunitinib in Patients with TKIs-resistant RCC
Recruiting
This is a Phase I/II open-label, efficacy and safety study of bicalutamide in combination with sunitinib in patients with advanced renal cell carcinoma (RCC) who have been treated with a receptor tyrosine kinase inhibitor (RTKI) and experienced disease progression.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: UB/ Great Lakes Cancer Care, Buffalo, New York
Conditions: Carcinoma, Renal Cell
Intermittent Fasting in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Recruiting
This is a a pilot study to assess the feasibility of intermittent caloric restriction (plus a plant-enriched diet optionally) in prostate cancer patients receiving androgen deprivation therapy. Study feasibility measures will include enrollment rate, drop-out rate and compliance with diet measured by self-reports.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: University at Buffalo/Great Lakes Cancer Center, Buffalo, New York
Conditions: Prostate Cancer
REBYOTA™ Prospective Registry
Recruiting
This is a prospective observational cohort study designed to collect data on patients who received REBYOTA™ for the prevention of rCDI in the routine care setting. As all data collected for this study are observational, the decision to prescribe REBYOTA™ is at the treating physician's discretion and independent from the decision to enroll the patient in the study. Data will be collected from patients' medical records after obtaining informed consent. Data about clinical history, CDI events (prim... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: Ferring Investigational Site, New York, New York
Conditions: Recurrence of Clostridium Difficile Infection
Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study
Recruiting
The objective of this study is to determine if a combination of oral nicotinamide and pyruvate (N\&P) can maintain eye health as compared to placebo while standard-of-care intraocular pressure-lowering glaucoma medications are used to treat glaucoma. A total of up to 188 participants will be enrolled and randomized 1:1 to receive N\&P or placebo for 87 weeks (20 months). Participants will be followed for a total of 91 weeks (21 months).
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
02/13/2025
Locations: ColumbiaDoctors Ophthalmology - 880 Third Avenue, New York, New York
Conditions: Primary Open Angle Glaucoma
A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Diet in Cancer Patients Receiving Chemotherapy
Recruiting
Caloric restriction may alter the response to chemotherapy induced stress response and enhance its antitumor effect. This study intends to use an intermitted caloric restriction protocol with alternate days before the chemotherapy administration to enhance the cytotoxic effect generated by standard treatment of cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: University at Buffalo / Great Lakes Cancer Care, Buffalo, New York
Conditions: Medical Oncology, Integrative Oncology, Medical Nutrition Therapy