New York is currently home to 4470 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma
Recruiting
The purpose of this study is to better understand why pancreatic cancer develops in some people who are known carriers of the gene mutation (an abnormality) called BRCA, or its close relative PALB2. The investigators hope to do this by establishing a BRCA/PALB2 mutation carriers Pancreatic Ductal Adenocarcinoma (the common form of pancreatic cancer) Registry. A registry is a database of information.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
12/27/2024
Locations: Cold Springs Harbor Laboratory (Specimen Analysis), Cold Spring Harbor, New York
Conditions: Pancreatic Ductal Adenocarcinoma
R-MVST Cells for Treatment of Viral Infections
Recruiting
The primary objective is to determine the safety and feasibility of administering R-MVST cells to patients with refractory viral reactivation and/or symptomatic disease caused by Epstein Barr Virus (EBV), cytomegalovirus (CMV), adenovirus (ADV) or BK virus. R-MVST cells will be generated on-demand from the closest partially human leukocyte antigen (HLA)-matched (minimum haploidentical) healthy donors or from the original allo-transplant donor if available. The investigator will closely monitor t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/26/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Epstein-Barr Virus Infections, Cytomegalovirus Infections, Adenovirus, BK Virus Infection
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
Recruiting
The goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to the research community. To accomplish these goals, we will enroll 800 Amyotrophic Lateral Sclerosis (ALS) patients and 200 healthy controls from sites globally, over a 5 year time frame. Additionally, speech and motor function and spirometry measures will be collected bi-w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/26/2024
Locations: Columbia University, New York, New York
Conditions: Amyotrophic Lateral Sclerosis, Movement Disorders, Degenerative Disorder, Motor Neuron Disease
Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes
Recruiting
Cigarette smoking is now the leading killer of people with HIV (PWH) in the US, and most cessation strategies tried to date have failed to increase long-term quit rates. An "all or none" approach to smoking cessation in PWH offers little benefit to the large majority of PWH who are unable or unwilling to quit. In this proposal we argue that a harm reduction approach (i.e. cut down, get screened for lung cancer, control your blood pressure and cholesterol) has the potential to yield significant b... Read More
Gender:
ALL
Ages:
Between 40 years and 79 years
Trial Updated:
12/24/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Hiv, Tobacco Use
Central Line Study
Recruiting
Two different techniques for placing a central venous catheter will be compared. The studyu team hypothesizes that clinicians randomized to the peripheral catheter technique will have higher first attempt success rates, fewer procedural complications, and a shorter mean time to procedure completion than physicians assigned to wire through hollow bore needle.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/24/2024
Locations: Montefiore, Bronx, New York
Conditions: Shock
Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting
Recruiting
This is a double blind active placebo controlled clinical trial for individuals within an inpatient setting with moderate to severe depression. The purpose of this study is to assess if nebulized ketamine can reduce depressive symptoms.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
12/23/2024
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Severe Depression, Moderate Depression, Ketamine, Midazolam, Peripheral Nervous System Agents, Central Nervous System Agents, Neurotransmitter Agents, Physiologic Effects of Drugs, Sensory System Agents, Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal, Depressive Symptom, Hypnotics and Sedatives, Anti-anxiety Agents, Tranquilizing Agents, Psychotropic Drugs, Anesthetics Agent, GABA Modulators, GABA Agents
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Recruiting
The goal of this clinical trial is to learn if KQB198 works to treat advanced solid tumor cancer in adults. It will also learn about the safety of KQB198. The main questions it aims to answer are: * What is the safe dose of KQB198 by itself or in combination with other anti-cancer drugs? * Does KQB198 alone or in combination with other anti-cancer drugs decrease the size of the tumor? * What happens to KQB198 in the body? Participants will: * Take KQB198 daily, alone or in combination with an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/23/2024
Locations: Memorial Sloan Kettering Cancer Center, Long Island City, New York
Conditions: Solid Tumor, Adult
Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement
Recruiting
The goal of this clinical trial is to test the BrightPoint Epidural device as the first system to use multispectral reflectometry to find the epidural space in lumbar neuraxial procedures requiring epidural needle. The main questions it aims to answer are: 1. Is the device a qualitatively effective secondary confirmation of Loss of Resistance? 2. Is the device a qualitatively effective training tool for educating trainees in how to perform lumbar epidurals? Participants will undergo a neuraxia... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
12/23/2024
Locations: Hospital for Special Surgery, New York, New York
Conditions: Lumbar Spine Surgery
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
Recruiting
The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is: 1. Is there a difference in opioid consumption 24-48 hours post block administration among patients that receive an adductor canal catheter (ACC) versus adductor canal block (ACB)? Participants will be: * Randomized to receive an adductor canal catheter (ACC) or a sham adductor canal catheter.... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/23/2024
Locations: Hospital for Special Surgery, New York, New York
Conditions: Chronic Pain, Opioid Use, Adductor Canal Block, Total Knee Arthroplasty
Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty
Recruiting
The goal of this randomized controlled trial is to examine if there is a relationship between the addition of the genicular nerve block and anterior femoral cutaneous nerve block in providing analgesia and the use of oral and intravenous medication in patients undergoing a total knee arthroplasty. The main questions it aims to answer are: 1. Does incorporating genicular nerve block and anterior femoral cutaneous nerve block to our current standard of care reduce patients' total opioid consumpti... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/23/2024
Locations: Hospital for Special Surgery, New York, New York
Conditions: Total Knee Replacement, Genicular Nerve Block, Opioid Use
Infrared Images for Spinal Cord Stimulation in Complex Regional Pain Syndrome Patients
Recruiting
The goal of this observational study is to compare thermal camera Forward Looking InfraRed (FLIR) images before and after spinal cord stimulation to evaluate the difference in sympathetic activity of the affected limb in patients with complex regional pain syndrome (CRPS). The main questions it aims to answer are: Question 1: Can Infrared (FLIR) imaging be used to monitor the sympatholytic activity caused by Spinal Cord Stimulation (SCS) in patients with CRPS? Question 2: Is there any correlat... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
12/23/2024
Locations: Hospital for Special Surgery, New York, New York
Conditions: Complex Regional Pain Syndromes
Updated Diagnostic Cortisol Values for Adrenal Insufficiency
Recruiting
The purpose of this study is to determine the cortisol levels that most accurately diagnose a patient with adrenal insufficiency, a condition in which cortisol levels are too low for daily living.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/23/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Adrenal Insufficiency