New York is currently home to 4507 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy
Recruiting
This study will compare two methods of electrical stimulation (alternating current and direct current) as an adjunctive therapy to treating lumbosacral radiculopathy. Both types of electrical stimulation have been used in clinical practice for physical therapy, however direct current stimulation is much less common and there is less known about its impact on physical therapy outcomes. The aim of this project is to show the efficacy of a novel device, the Neubie direct current device, compared to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Hands On Physical Therpay, Astoria, New York
Conditions: Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites
Stick2PrEP Cisgender Women and Trans Individuals
Recruiting
Taking a daily anti-HIV pill can protect people from HIV infection. This is called preexposure prophylaxis \[PrEP\]. Many cisgender women and trans individuals do not know this medication is available; others struggle to take the pill every day. It is important to understand attitudes and preferences about HIV prevention options, especially as new options become available. This study plans to evaluate preferences over time among cisgender women and trans individuals who are taking medication to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: HIV Prevention, Pre-exposure Prophylaxis
Efficacy of Non-invasive Vagus Nerve Stimulation for Treatment of Low Weight Eating Disorders
Recruiting
This project includes a 4-week randomized trial comparing pre-meal vagal nerve stimulation (taVNS) to pre-meal sham stimulation. The aims will assess if taVNS results in greater satisfaction, greater calorie consumption, less self-reported fullness, decrease in eating disorder symptoms, and less anxiety than sham stimulation.
Gender:
ALL
Ages:
Between 14 years and 22 years
Trial Updated:
07/24/2024
Locations: Department of Psychiatry, Eating and Weight Disorders Program, New York, New York
Conditions: Anorexia Nervosa
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Recruiting
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Clinical Research Alliance, Lake Success, New York
Conditions: Diffuse Large B-cell Lymphoma
Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma
Recruiting
This study will assess the safety, tolerability, pharmacokinetics (PK) and the therapeutic potential of HDP-101 in patients with plasma cell disorders including multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: Mount Sinai, The Tisch Cancer Instutute, New York, New York
Conditions: Multiple Myeloma, Plasma Cell Disorder
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
Recruiting
The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, ≥12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure and heart rate, time to onset and to maximal response, and the duration of response; to assess the safety of the product in this population; and to character... Read More
Gender:
ALL
Ages:
Between 12 years and 16 years
Trial Updated:
07/22/2024
Locations: Stony Brook Medicine, Stony Brook, New York
Conditions: Hypotension
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry
Recruiting
This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients aged from 6 months to 17 years of age who are undergoing an in-office ear tube placement procedure (tympanostomy) using the Tula® System. The Registry will include up to 20 centers in the US and up to 200 patients for the initial evaluation. The FDA-approved Tula System includes the Tula Iontophoresis System (IPS) with TYMBION™ otic anesthetic for local anesthesia of the ea... Read More
Gender:
ALL
Ages:
Between 6 months and 17 years
Trial Updated:
07/19/2024
Locations: Columbia University Vagelos College of Physicians and Surgeons, New York, New York
Conditions: Otitis Media With Effusion, Acute Otitis Media, Otitis Media
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Recruiting
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.
Gender:
ALL
Ages:
20 years and below
Trial Updated:
07/19/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant Disorders
Task Specific Training for Advanced Multiple Sclerosis
Recruiting
The purpose of this study is to find effective physical therapy treatments for individuals who have severe multiple sclerosis. Physical therapy treatments for mild-to-moderate multiple sclerosis exists, however, very limited research has been done for physical therapy for severe multiple sclerosis (MS). In this study 10 participants diagnosed with severe MS will engage in 1-hour physical therapy sessions twice a week for 6 weeks to address limitations in standing, balancing, and bed mobility.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/18/2024
Locations: Hunter College, Physical Therapy Department, City University of New York, New York, New York
Conditions: Multiple Sclerosis
MYLUNG Consortium Part 3: Observational Study
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: New York Oncology Hematology, P.C., Albany, New York
Conditions: Carcinoma, Non-Small-Cell Lung
TENS Treatment for Bedwetting
Recruiting
Children referred to pediatric urology clinic for primary nocturnal enuresis will be screened for enrollment. Patients who fail will next be offered therapy with a bedwetting alarm device or a TENS unit as an alternative, and those who chose TENS therapy will be included in the study.The patients will be randomized into three groups of 30 patients each. Group 1 will be the long frequency set at 2 Hz (hertz). Group 2 will be the moderate frequency set at 10 Hz. Group 3 will be the short frequency... Read More
Gender:
ALL
Ages:
Between 5 years and 18 years
Trial Updated:
07/17/2024
Locations: Albany Medical College, Albany, New York
Conditions: Nocturnal Enuresis, Bed Wetting
Eccentric Exercise and Fatigue in Multiple Sclerosis
Recruiting
The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric re... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/16/2024
Locations: Hunter College, Physical Therapy Department, City University of New York, New York, New York
Conditions: Multiple Sclerosis, Fatigue