New York is currently home to 4436 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD)
Recruiting
This is a comparative effectiveness study of two pragmatic models aiming to introduce palliative care for end stage liver disease patients. The 2 comparators are: Model 1: Consultative Palliative Care (i.e. direct access to Palliative Care provider), Model 2: Trained Hepatologist- led PC intervention (i.e. a hepatologist will receive formal training to deliver Palliative Care services) Primary Outcome: The change in quality of life from baseline to 3 months post enrollment as assessed by FACT-... Read More
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
04/05/2022
Locations: VA Bronx, Bronx, New York
Conditions: End Stage Liver Disease
Non Exudative AMD Imaged With SS-OCT- Extension
Recruiting
The investigators wish to better understand the role of the choriocapillaris (CC) in the formation and progression of non-exudative in age related macular degeneration (armd) by imaging the retinal pigment epithelium (rpe) and the choroidal microvasculature and by studying their inter-dependence to determine if the loss of the CC could prove useful as an anatomic clinical trial endpoint in future drug trials.
Gender:
ALL
Ages:
All
Trial Updated:
03/08/2022
Locations: Vitreous Retina Macular Consultants of NY, New York, New York
Conditions: Dry Macular Degeneration
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, New York, New York
Conditions: Chronic Lymphocytic Leukemia
A Prospective Biomarker Study in Active SPMS Subjects Treated With Cladribine Tablets
Recruiting
The purpose of this study is to explore the concept that biomarker sensitivity will detect activity in Multiple Sclerosis (MS) subjects and allow appropriate change in treatment to prevent dysfunction.
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
01/12/2022
Locations: Multiple Sclerosis Center of Northeastern New York, P.C., Latham, New York
Conditions: Multiple Sclerosis
COVID-19 Administration of Single-Dose Subcutaneous Anti- Spike(s) SARS-CoV-2 Monoclonal Antibodies Casirivimab and Imdevimab in High-Risk Pediatric Participants Under 12 Years of Age
Recruiting
The primary objective of the study is to characterize the concentrations of casirivimab+imdevimab in serum over time after a single subcutaneous (SC) administration The secondary objectives of the study are: To assess the safety and tolerability of SC or single administration of casirivimab+imdevimab To assess the occurrence of grade ≥3 injection site reactions and grade ≥3 hypersensitivity reactions, in participants treated with SC doses of casirivimab+imdevimab To assess the immunogenicity o... Read More
Gender:
All
Ages:
12 years and below
Trial Updated:
12/06/2021
Locations: Jacobi Medical Center, Bronx, New York
Conditions: COVID-19
Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System
Recruiting
An early feasibility study to evaluate the safety and performance of 1) the transcatheter delivery and implantation of the Cardiac Implants (CI) annuloplasty ring and 2) the adjustment of the ring approximately 90 days following implantation in patients suffering from ≥ moderate functional tricuspid regurgitation (FTR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2021
Locations: Weill Cornell Medicine-New York Presbyterian Hospital, New York, New York
Conditions: Tricuspid Regurgitation Functional
The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
Recruiting
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for HCT will be screened by NGS-MRD on a test of bone marrow done before the HCT. Subjects who are pre-HCT NGS-MRD negative will be eligible to receive a non-TBI conditioning regime... Read More
Gender:
ALL
Ages:
Between 1 year and 25 years
Trial Updated:
08/20/2021
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: B-cell Acute Lymphoblastic Leukemia
Delphi Early Feasibility Study
Recruiting
An early feasibility study to evaluate the safety and first pass effect technical assessment of Delphi Revascularization Device for clot retrieval in Anterior circulation ischemic stroke in the intracranial ICA, MCA M1 and proximal dominant MCA M2, up to 8hrs of symptom onset or Last Known Well (LKW).
Gender:
All
Ages:
18 years and above
Trial Updated:
08/19/2021
Locations: kaledia Health/Buffalo General Medical Center/GVI, Buffalo, New York
Conditions: Ischemic Stroke
A Cross Over Pilot Study of Abobotulinum Toxin A (Dysport) as a Treatment for Task-dependent Upper Limb Tremor
Recruiting
Task-dependent upper limb tremor is a disorder that frequently impairs patients' function and quality of life. Few studies exist that quantify the improvements in motor performance and disability with botulinum toxin (injections). The study team aims to perform an exploratory pilot trial using toxin Type A (Dysport) in 25 patients with task-dependent upper limb tremor, to refine quantitative measures of performance using blinded video analysis, demonstrate efficacy and tolerability of injections... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/23/2021
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Tremor, Limb
Use of ReDS Technology in Patients With Acute Heart Failure
Recruiting
Background: Fluid overload, especially pulmonary congestion, is one of the main contributors into heart failure (HF) readmission risk and it is a clinical challenge for clinicians. The Remote dielectric sensing (ReDS) system is a novel electromagnetic energy-based technology that can accurately quantify changes in lung fluid concentration noninvasively. Previous non-randomized studies suggest that ReDS-guided management has the potential to reduce readmissions in HF patients recently discharged... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2021
Locations: Mount Sinai Hospital, New York, New York
Conditions: Heart Failure, Lung Congestion
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, New York, New York
Conditions: Ulcerative Colitis
Proton or Photon RT for Retroperitoneal Sarcomas
Recruiting
This research study is a Phase I clinical trial. Phase I clinical trials test the safety of an investigational intervention. Phase I studies also try to define the appropriate dose of the investigational therapy to use for further studies. "Investigational" means that the intervention is still being studied and that research doctors are trying to find out more about it. Retroperitoneal sarcomas are soft tissue tumors located at the far back of the abdomen. Typically, patients with retroperitone... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/01/2020
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Retroperitoneal Sarcoma