New York is currently home to 4480 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Mobility Opportunities Via Education/Experience (MOVE): Healthcare Impact Assessment
Recruiting
The purpose of this study is to determine whether participation in the Mobility Opportunities Via Education (MOVE) program is associated with reduced use of healthcare for individuals with developmental disabilities.
Gender:
ALL
Ages:
Between 5 years and 65 years
Trial Updated:
05/08/2023
Locations: Center for Disability Services, Albany, New York
Conditions: Quality of Life, Health Care Utilization
Eye Movement Rehabilitation in Low Vision Patients
Recruiting
Approximately 217 million people worldwide currently suffer from low vision, which impacts a broad range of activities of daily living and is associated with depression and increased mortality. Over half of the patients presenting for low vision services have eye disease that affects the fovea and surrounding macula and leads to central vision loss (CVL). People with CVL are forced to use eccentric vision as a substitute for their impaired fovea, however eye movement control and visual function... Read More
Gender:
ALL
Ages:
Between 14 years and 99 years
Trial Updated:
05/02/2023
Locations: Lighthouse Guild, New York, New York
Conditions: Low Vision, Age Related Macular Degeneration
Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
Recruiting
This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound complications and medical costs in patients undergoing lower extremity amputation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2023
Locations: Westchester Medical Center, Valhalla, New York
Conditions: Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma, Wound Infection, Surgical, Lymph Leakage
KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
Recruiting
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition of MDM2 is a novel mechanism of action in MF. This study will be conducted in 2 phases. Phase 2 will determine the KRT-232 recommended dose and dosing schedule; Phase 3 will test KRT-232 vs Best Available Therapy (BAT). Patients in the Phase 3 part of the study will be randomized 2:1 to receive ei... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/26/2023
Locations: Brookdale University Hospital and Medical Center, Brooklyn, New York
Conditions: Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Post-Essential Thrombocythemia MF (Post-ET-MF)
Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke
Recruiting
To determine whether treatment with transauricular vagus nerve stimulation (taVNS) during the training of an affected upper limb of a patient with chronic stroke on a robotic motor task alters the motor impairment.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/19/2023
Locations: Feinstein Institutes at Northwell Health, Manhasset, New York
Conditions: Stroke, Hemiparesis
Continuous Vital Sign Monitoring in Newborns
Recruiting
This study evaluates the feasibility and usability of continuous wireless vital sign monitoring of well newborns during their birth hospitalization.
Gender:
ALL
Ages:
Between 0 hours and 12 hours
Trial Updated:
04/14/2023
Locations: Cohen Children's Medical Center of New York, New Hyde Park, New York
Conditions: Newborn Complication
Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®
Recruiting
This study is the first step in testing the hypothesis that adding Photobac® Photodynamic Therapy to surgical removal of a glioblastoma or gliosarcoma will be both safe and effective. Photodynamic Therapy (PDT) combines light and a photosensitizer. PDT has been used to treat a variety of cancers with varying degrees of success. For the past thirty years Photolitec has been working to develop a treatment for glioblastoma or gliosarcoma using light and a photosensitizer. Photolitec's scientists... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2023
Locations: Roswell Park Cancer, Buffalo, New York
Conditions: Glioblastoma Multiforme of Brain, Glioma, Sarcomatous
Evaluation of Depression and Anxiety in Chemotherapy Patients
Recruiting
This study will examine the existence and severity of depression and anxiety in patients undergoing chemotherapy at RUMC. Patients currently undergoing initial chemotherapy cycle will be compared to patients undergoing a subsequent chemotherapy cycle. Data will then be collected using standardized depression and anxiety scales to assess if these comorbidities exist and to what severity level. Data already collected for depression and anxiety in patients with chronic, but not cancer, illness will... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/31/2023
Locations: Richmond University Medical Center, Staten Island, New York
Conditions: Oncology Problem
Physica System Total Knee Replacement Registry Study
Recruiting
The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/17/2023
Locations: Syracuse Orthopedic Specialists, Syracuse, New York
Conditions: Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population
Recruiting
This is an observational research study. Patients with rectal cancer can choose different courses of treatment. This study will follow these patients over the course of approximately six years, depending on their treatment. Patients will be monitored through clinic visits and survey assessments to see how they do, how they feel regarding their treatment choices, and their outcomes. The surveys will analyze the impact of the patients' treatment choices, as well as patient adherence, in a rural se... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2023
Locations: Bassett Healthcare Network, Cooperstown, New York
Conditions: Rectal Cancer
Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT
Recruiting
The purpose of this study is to evaluate the safety and the efficacy of SMART101 (Human T Lymphoid Progenitor (HTLP)) injection to accelerate immune reconstitution after T cell depleted allogeneic hematopoietic stem cell transplantation (HSCT) in adult and pediatric patients with hematological malignancies.
Gender:
ALL
Ages:
All
Trial Updated:
03/02/2023
Locations: Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York
Conditions: Hematological Malignancies
Navtemadlin (KRT-232) With or Without Anti-PD-1/Anti-PD-L1 for the Treatment of Patients With Merkel Cell Carcinoma
Recruiting
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Merkel Cell Carcinoma (MCC) who have failed treatment with at least one anti-PD-1 or anti-PD-L1 immunotherapy or in combination with avelumab in MCC patients who are anti-PD-1 or anti-PD-L1 treatment naïve. Inhibition of MDM2 is a novel mechanism of action in MCC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: Memorial Sloan-Kettering Cancer Center, New York, New York
Conditions: Merkel Cell Carcinoma