New York is currently home to 4784 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Proton or Photon RT for Retroperitoneal Sarcomas
Recruiting
This research study is a Phase I clinical trial. Phase I clinical trials test the safety of an investigational intervention. Phase I studies also try to define the appropriate dose of the investigational therapy to use for further studies. "Investigational" means that the intervention is still being studied and that research doctors are trying to find out more about it. Retroperitoneal sarcomas are soft tissue tumors located at the far back of the abdomen. Typically, patients with retroperitone... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/01/2020
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Retroperitoneal Sarcoma
Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization
Recruiting
This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). Subjects will be followed for up to 60 months post index procedure.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/31/2020
Locations: Columbia University Medical Center/NYPH, New York, New York
Conditions: Peripheral Arterial Disease
Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: Neurobehavioral Research Inc, Cedarhurst, New York
Conditions: Schizophrenia
Prospective Randomized Controlled Trial Describing the Recurrence Rate of Adenomas in Sessile or Flat Colonic Lesions 15mm or Larger Receiving Post-resection Site Treatment With Snare Tip Soft Coagulation
Recruiting
A multi-center randomized controlled trial in only 24 patients showed a significant reduction of the recurrence rate by treatment of the normal appearing perimeter of the EMR defect using the argon plasma coagulator (2). A recent non-randomized trial suggested a substantial reduction by treatment of the perimeter with the snare tip in the soft coagulation mode (3).
Gender:
All
Ages:
Between 25 years and 99 years
Trial Updated:
08/07/2020
Locations: NYU Langone Health, New York, New York
Conditions: Colon Polyp
Development of Childhood Anti-influenza Immunity
Recruiting
More information is needed on how children fight off influenza virus, as they are at greater risk for developing severe influenza infection and tend to have weaker responses to influenza vaccination. The purpose of this study is to understand how a child's early exposure to influenza vaccine or infection with influenza virus prepares him or her to combat future infections with this virus. Investigators will learn about how protection develops following an influenza infection or vaccination and t... Read More
Gender:
All
Ages:
Between 3 months and 15 years
Trial Updated:
07/15/2020
Locations: University of Rochester, Rochester, New York
Conditions: Influenza, Human
A Trial of CONvalescent Plasma for Hospitalized Adults With Acute COVID-19 Respiratory Illness
Recruiting
There is currently no treatment available for COVID-19, the acute respiratory illness caused by the novel SAR-CoV-2. Convalescent plasma from patients who have recovered from COVID-19 that contains antibodies to the virus is a potential therapy. On March 25th, 2020, the FDA approved the use of convalescent plasma under the emergency investigational new drug (eIND) category. Randomized trials are needed to determine the efficacy and safety of COVID-19 convalescent plasma for acute COVID-19 infect... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
07/06/2020
Locations: Brooklyn Methodist Hospital, Brooklyn, New York
Conditions: COVID-19
CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
Recruiting
The purpose of this study is to learn more about the effects of (classification determinant) CD34+ stem cell selection on graft versus host disease (GVHD) in children, adolescents, and young adults. CD34+ stem cells are the cells that make all the types of blood cells in the body. GVHD is a condition that results from a reaction of transplanted donor T-lymphocytes (a kind of white blood cell) against the recipient's body and organs. Study subjects will be offered treatment involving the use of t... Read More
Gender:
All
Ages:
22 years and below
Trial Updated:
06/17/2020
Locations: Columbia University Medical Center, New York, New York
Conditions: Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)
Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML
Recruiting
A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy and bone marrow transplantation in newly diagnosed AML subjects with FLT3 mutation. About 510 subjects will be randomized in a 1:1 ratio to receive either crenolanib in addition to standard first line treatment of AML (chemotherapy and if eligible, transplantation) (arm A) or midostaurin and standard treat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2020
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Newly Diagnosed FLT3 Mutated AML
Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)
Recruiting
The purpose of this study is to test the hypothesis that post-exposure prophylaxis with hydroxychloroquine will reduce the symptomatic secondary attack rate among household contacts of known or suspected COVID-19 patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2020
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: COVID-19, Corona Virus Infection
Pulmonary Hypertension Association Registry
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: Weill Cornell Medical Center, New York, New York
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
Metformin in Heart Failure Without Diabetes
Recruiting
Columbia University Medical Center is conducting a pilot clinical research study that will assess the use of the medication metformin for heart failure in patients who are not diabetic and have no evidence of insulin resistance. Patients will received either the study drug metformin or placebo for 4 months. During the study, the patients will undergo extensive testing that will include symptom assesment, exercise capacity, echocardiography, cardiac PET imaging and blood tests.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/06/2020
Locations: New York Hospital - Columbia University Irving Medical Center, New York, New York
Conditions: Heart Failure
A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery
Recruiting
To evaluate the safety and ocular efficacy of Dextenza in combination with an intracameral antibiotic and NSAID in controlling post-operative ocular pain and inflammation compared to standard of care topical therapy in patients undergoing bilateral cataract surgery.
Gender:
All
Ages:
Between 22 years and 100 years
Trial Updated:
12/17/2019
Locations: Ophthalmic Consultants of Long Island, Garden City, New York
Conditions: Patient Preference