Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer
Recruiting
This is a prospective, single-institution, single-arm, phase II clinical trial that tests a novel strategy of neoadjuvant Sasanlimab, an immune checkpoint inhibitor (ICI), in combination with stereotactic body radiation therapy as an in-situ vaccination in patients, who are ineligible to receive cisplatin-based chemotherapy and undergoing radical cystectomy for muscle-invasive bladder cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2024
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Urothelial Carcinoma Bladder
A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium
Recruiting
The objective is to evaluate the safety and efficacy of low dose and high dose CBT-001 eye drop dosed twice daily for 24 months compared to vehicle in reducing conjunctival hyperemia and preventing pterygium progression in eyes with pterygia.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/29/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Pterygium
Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
Recruiting
This study is part of the development and validation of a non-invasive lung screening test which aim to identify early stage lung cancer in patients at high risk for lung cancer.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
03/28/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: Lung Cancer
Volume Outcome Relationships and Effects
Recruiting
This is a retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with esophageal cancer than low-volume facilities.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Methodist Richardson Medical Center, Richardson, Texas
Conditions: Esophageal Cancer
Pelvic Angioembolization: A Prospective Multi-Institutional Study (Data From All Campuses Will be Used)
Recruiting
The investigator's propose a multicenter prospective observational study to investigate the use of embolization in patients with negative angiogram and to ascertain the optimal level of treatment when the angiogram is positive; non-selective vs. selective embolization.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Pelvic Hemorrhage
Perceived Coping, Meaning, and Joy at Work
Recruiting
The aim of this study is to assess and describe employee characteristics associated with perceived horizontal inter-collegial workplace uncivil behavior within nursing services, and identify any relationships with meaning and joy in work (MJW), and assess job satisfaction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Methodist Richardson Medical Center, Richardson, Texas
Conditions: Undefined
Safety and Efficacy of Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
Recruiting
The purpose of this study is to evaluate the efficacy, safety, and adequacy of Endoscopic Ultrasound (EUS) Portal Pressure Gradient Measurement (PPGM) in patients undergoing EUS-guided liver biopsies.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/26/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Liver Diseases
Analysis of Donor-derived Cell Free DNA in Liver Transplant Patients
Recruiting
Determine the levels of Donor-derived (dd)cell-free DNA(cfDNA )in liver transplant recipients with normal liver function tests (LFTs) indicating stable immunosuppression status (IS). Based on this range use the dd-cfDNA levels to determine over or under IS in liver transplant patients to make changes to their IS medication regimen.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Liver Transplant Failure
Clopidogrel Hyper-Responsiveness: Incidence and Associated Outcomes in Patients With Cerebral Aneurysms
Recruiting
This registry study will investigate the incidence of and outcomes associated with clopidogrel hyper-responsive patients treated at Methodist Dallas Medical Center, beginning in January 2018, who suffered cerebral aneurysms.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/26/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Cerebral Aneurysm
Hepatic Transplantation Registry
Recruiting
The objective is to provide a mechanism to store information regarding the demographic characteristics; pre-, intra-, and post-transplant laboratories; treatment strategies; complications; and outcomes in patients undergoing hepatic transplantation.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/26/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Identify More Accurate Predictive Models of Transplant Risk to Monitor and Evaluate New and Existing Patient Factors
Outcomes Using MARS for Patients With ALF
Recruiting
Retrospective chart review will be conducted on patients at Methodist Dallas Medical Center, meeting the inclusion criteria from January 1, 2019 to December 15, 2020 to determine the transplant free survival and overall survival and other secondary outcome measures.
Gender:
ALL
Ages:
All
Trial Updated:
03/26/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Alcoholic Hepatitis, Acute Liver Failure
Head and Neck Trauma Registry, Protocol ID: 032.MBSI.2021.D
Recruiting
This is a retrospective registry dataset of all adults who presented with cervical and/or skull base fractures or a subdural hematoma at Methodist Dallas Medical Center (MDMC) and had consults to the neurological surgery department beginning in January of 2016, and continuing until a statistically significant number of cases are obtained.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Methodist Moody Brain and Spine Institute, Methodist Dallas Medical Center, Dallas, Texas
Conditions: Craniocerebral Trauma