Texas is currently home to 4852 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow
NCT04865718
Recruiting
The purpose of this research study is to evaluate the ability of laser speckle contrast imaging to visualize blood flow in real time during neurosurgery. Real-time blood flow visualization during surgery could help neurosurgeons better understand the consequences of vascular occlusion events during surgery, recognize potential adverse complications, and thus prompt timely intervention to reduce the risk of stroke. The current standard for visualizing cerebral blood flow during surgery is indocya... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: Dell Seton Medical Center, Austin, Texas
Conditions: Aneurysm, Brain, Arteriovenous Malformation of Brain, Neurovascular Disorder
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Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors
NCT04450732
Recruiting
Phase I Dose Finding Study for GQ1001 in Patients with HER2-Positive Advanced Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2023
Locations: M.D. Anderson Cancer Center, Houston, Texas
Conditions: HER2-positive Breast Cancer, HER2-positive Biliary Tract Cancer, HER2-Positive Salivary Gland Carcinomas, HER2-Positive Advanced Solid Tumor
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Complex Abdominal, TAAA, Aortic Arch Aneurysm or Dissections With Fenestrated/Branched Stent Graft
NCT02089607
Recruiting
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Complex Abdominal Aortic Aneurysm, Aortic Arch Dissection
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Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts
NCT01937949
Recruiting
The purpose of this study is to evaluate clinical outcomes and quality of life measures in treated by endovascular aortic repair of juxtarenal, suprarenal, and type IV thoracoabdominal aortic aneurysms using custom-made Cook Zenith® Fenestrated AAA Endovascular Graft.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms, Type IV Thoracoabdominal Aortic Aneurysms
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Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension
NCT05881252
Recruiting
The purpose of this study is observe outcomes before and after a change in clinical practice in the threshold for management of severe hypertension in pregnancy and the post-partum period. Outcomes will be observed for 10 months under the current (traditional) clinical blood pressure threshold for acute treatment of hypertension, which is \>= 160 millimeters of mercury (mmHg) systolic blood pressure (SBP). This will be followed by one month of education about rationale for the new SBP threshold... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
12/01/2023
Locations: UT Houston, Houston, Texas
Conditions: Maternal Hypertension
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Laparoscopic Incision Closure s in Obese Patients
NCT05622110
Recruiting
Several methods for closure of trocar wounds are known in laparoscopic surgery including mostly transcutaneous or subcuticular suture or adhesive paper tape. Studies comparing laparoscopic incision closure in bariatric population are limited .This is a prospective study that will be conducted in a single tertiary medical center. s obese population comprise most of our surgical candidates, and due to the aforementioned, the aim of our study is to compare the outcomes of both techniques in obese w... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/01/2023
Locations: University of Texas, Houston, Texas
Conditions: Obesity, Incision, Surgical
Register for Updates
Solution Temperature and Fluid Deficit During Hysteroscopy
NCT05622097
Recruiting
Hysteroscopic surgery is widely used for the treatment of gynecological diseases, such as septum, synechiae, polyp and intrauterine fibroids. The complication rate is estimated as 0.22% and includes uterine perforation, massive bleeding, and fluid overload. Operative hysteroscopy intravascular absorption (OHIA) syndrome refers to fluid overload complications from operative hysteroscopies and is considered a major complication. Report describing the clinical association between irrigation fluid t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/01/2023
Locations: University of Texas, Houston, Texas
Conditions: Surgery
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Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain Experience
NCT05074485
Recruiting
The first objective of the study is to evaluate whether a novel bio-signature (derived from a wide range of pro- and anti-nociceptive IL-1 family cytokine activity) will predict pain experienced and also release of underlying endogenous opioid neurotransmitters during an experimental nociceptive pain challenge, which will be performed while simultaneously quantifying mu-opioid receptor activity in the brain via \[11C\]-carfentanil PET neuroimaging in healthy subjects. Another objective is to eva... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/01/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Pain
Register for Updates
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
NCT03298802
Recruiting
Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
12/01/2023
Locations: St. David's North Austin Medical Center, Austin, Texas
Conditions: Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced, Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Register for Updates
Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse
NCT04151901
Recruiting
This project is a 2-phase, randomized clinical trial that includes 7 days of unilateral leg disuse (Phase 1), immediately followed by 14 days of bilateral leg rehabilitation (Phase 2). The investigators will recruit cohorts of healthy middle-aged men and women to address their aims: * Demonstrate the sex-specific effects of skeletal muscle disuse (Phase 1) * Identify key molecular determinates of susceptibility of skeletal muscle atrophy (Phase 1) * Map the early, sex-specific molecular time-co... Read More
Gender:
ALL
Ages:
Between 50 years and 65 years
Trial Updated:
11/30/2023
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Atrophy of Muscle Due to Disuse, Rehabilitation
Register for Updates
The International Registry for Leigh Syndrome
NCT03137355
Recruiting
The purpose of this study is to develop a database containing clinical and laboratory information for patients with Leigh syndrome. The goal is to provide a greater understanding of Leigh syndrome allowing further characterization of this disease.
Gender:
ALL
Ages:
Between 0 days and 100 years
Trial Updated:
11/30/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Leigh Syndrome, Leigh Disease, Leigh's Necrotizing Encephalopathy, Subacute Necrotizing Encephalomyopathy, Subacute Necrotizing Encephalomyelopathy
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A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Pinnacle Clinical Research - Austin, Austin, Texas
Conditions: Non-Alcoholic Fatty Liver Disease
Register for Updates