Texas is currently home to 4855 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluation of 4-Factor PCC in DOAC-associated Intracranial Hemorrhage
Recruiting
Intracranial hemorrhage (ICH) can occur due to traumatic and spontaneous events.1 The incidence of non-traumatic, spontaneous ICH is approximately 40,000 to 67,000 cases per year while the incidence of traumatic brain injury (TBI) is nearly 1.7 million annually
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/17/2023
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Intracranial Hemorrhage
Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA
Recruiting
Osteomyelitis is described as infection and inflammation of the long bone or bone marrow, often due to an open wound, operation, or invasive trauma.1 It is invasive and involves hematogenous seeding or contiguous spread of the infectious organism
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/17/2023
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Osteomyelitis
Rib Fracture Cryoanalgesia
Recruiting
Rib fractures lead to poor patient outcomes and even death 3. Data suggests effective pain management is crucial to obtain favorable outcomes 4, 5Current outpatient treatment modalities are limited to oral or topical medications with low efficacy and high risk for opioid dependence. In-patient management with a thoracic epidural TEA is largely considered the gold standard, but the risks of TEA may outweigh the benefits 6 to 8.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/17/2023
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Pain Management Improvement
Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
Recruiting
The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2023
Locations: Inquest Clinical Research, Baytown, Texas
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT
Recruiting
This is a study of a medical procedure that utilizes a commercially available catheter (the BullfrogĀ® Micro-Infusion Device) to locally deliver a commercially available anti-inflammatory drug (dexamethasone sodium phosphate injection) around the deep veins after DVT recanalization, where DVT symptoms were present for at least 14 days and no more than 60 days prior to recanalization. The goal of the study is to see if local anti-inflammation helps prevent re-thrombosis of the blood vessel and imp... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
10/17/2023
Locations: CardioVoyage, Denison, Texas
Conditions: Iliofemoral; Thrombosis
EASE: The Materna Prep Pivotal Study
Recruiting
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 12 months from the time of the use of the device d... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Vaginal Delivery, Pelvic Organ Prolapse
Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis
Recruiting
This is an observational study to understand the changes in alveolar dead space in medical critically ill patients with severe infection (severe sepsis) requiring mechanical ventilation and the possibility to predict multi-organ failure. The measurement of alveolar dead space used to require sophisticated equipment and time. New ventilators have microprocessors that allow rapid mathematical calculation with minimal intervention.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2023
Locations: Memorial Hermann Hospital, Houston, Texas
Conditions: Sepsis, Severe Sepsis, Septic Shock, Multi-organ Failure
Comparison of iLivTouch and FibroScan for the Assessment of Liver Fibrosis and Steatosis in Adult Patients in the US
Recruiting
This is a multi-center, cross-sectional, and prospective study that will recruit patients from multiple hospitals or outpatient clinics in the USA to the comparison of iLivTouch and FibroScan for the assessment of liver fibrosis and steatosis in adult patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2023
Locations: Baylor University, Houston, Texas
Conditions: Liver Fibrosis, Fatty Liver
Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations
Recruiting
This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metastatic) and with aberrant DNA repair gene mutations. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Bile Duct Adenocarcinoma, Fanconi Anemia Complementation Group Gene Mutation, Metastatic Bile Duct Carcinoma, PTEN Gene Deletion
The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
Recruiting
The purpose of this study is to examine the effect of 4 weeks of Citrulline supplementation on macro- and microvascular function during acute hyperglycemia in middle-aged and older adults with type 2 diabetes.
Gender:
ALL
Ages:
Between 40 years and 75 years
Trial Updated:
10/10/2023
Locations: TTU Kinesiology and Sport Management Building, Lubbock, Texas
Conditions: Type 2 Diabetes
AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Recruiting
The primary objective is to define the safety and tolerability of AB8939 in patients with AML by determining the dose-limiting toxicities, the maximum tolerated dose, and the recommended dose for dose expansion study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse, Myelodysplastic Syndrome Acute Myeloid Leukemia
FX Shoulder Prospective Clinical Study
Recruiting
Prospective Multi-Center Registry on study subjects with implanted devices marketed and legally commercialized in the USA by FX Shoulder Solutions.
Gender:
ALL
Ages:
All
Trial Updated:
10/05/2023
Locations: Texas Orthopedic Specialists, Bedford, Texas
Conditions: Osteoarthritis Shoulder, Rotator Cuff Syndrome of Shoulder and Allied Disorders, Fracture, Shoulder