Florida is currently home to 3776 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY to ASSESS the PERFORMANCE of the CORDIO HEARO SYSTEM
Recruiting
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: Nature Coast Clinical Research, Crystal River, Florida
Conditions: Heart Failure
Study of Plozasiran in Adults With Severe Hypertriglyceridemia
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with severe hypertriglyceridemia (SHTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo, and be evaluated for efficacy and safety. After Month 12, eligible participants will be offered an opportunity to continue in an optional open-label extension under a separate protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Innovative Research of West Florida, Inc., Clearwater, Florida
Conditions: Severe Hypertriglyceridemia
SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults with CD33 And/or FLT3 Blood Cancers Including AML/MDS
Recruiting
This is an open-label study of the safety, biodynamics, and anti-cancer activity of SENTI-202 (an off-the-shelf logic gated CAR NK cell therapy) in patients with CD33 and/or FLT3 expressing blood cancers, including AML and MDS.
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
03/25/2025
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: AML/MDS, CD33 Expressing Hematological Malignancies, FLT3 Expressing Hematological Malignancies
Parasitic Ulcer Treatment Trial
Recruiting
The Parasitic Ulcer Treatment Trial (PUTT) is a multi-center, parallel-group, randomized clinical trial. The purpose of this study is to determine whether including topical corticosteroids in a regimen for acanthamoeba keratitis (AK) will improve vision. Patients presenting to all enrollment centers with evidence of acanthamoeba keratitis will be eligible for the trial if there is evidence of ocular inflammation after 4 weeks of anti-amoebic therapy. Those who agree to participate will be random... Read More
Gender:
ALL
Ages:
8 years and above
Trial Updated:
03/25/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Acanthamoeba Keratitis
Can Immediate Post-injury Fluoxetine Improve the Recovery Trajectories of Victims in Bodily Trauma?
Recruiting
With this prospective double-blinded, placebo controlled clinical trial we hypothesize that immediate (post-injury) intervention with Fluoxetine will prevent/mitigate the development of negative psychiatric symptomology such as PTSD and depression for victims of bodily trauma. We also hypothesize that immediate use of Fluoxetine will decrease subjects' pain, pain interference and opioid use without changing our standard of care post-injury pain medication regimen. Enrolled subjects will be rando... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/25/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Musculoskeletal Injury
InfasurfAero™ Versus Sham Treatment in Preterm Newborns with RDS
Recruiting
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.
Gender:
ALL
Ages:
Between 29 weeks and 36 weeks
Trial Updated:
03/25/2025
Locations: University of Florida -Jacksonville, Jacksonville, Florida
Conditions: Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
Recruiting
The goal of this clinical study is to test how edecesertib (formerly known as GS-5718) can be useful in treating Cutaneous Lupus Erythematosus (CLE) in participants with CLE. Information on what is happening in the body relating to CLE, how the body processes, is affected by and responds to the study drug, and any study drug side effects will also be collected in this study.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/25/2025
Locations: Clinical Research of West Florida, Inc., Clearwater, Florida
Conditions: Cutaneous Lupus Erythematosus (CLE)
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants
Recruiting
Patent Ductus Arteriosus is a developmental condition commonly observed among preterm infants. It is a condition where the opening between the two major blood vessels leading from the heart fail to close after birth. In the womb, the opening (ductus arteriosus) is the normal part of the circulatory system of the baby, but is expected to close at full term birth. If the opening is tiny, the condition can be self-limiting. If not, medications/surgery are options for treatment. There are two ways... Read More
Gender:
ALL
Ages:
Between 7 days and 32 days
Trial Updated:
03/25/2025
Locations: Joe DiMaggio Children's Hospital, Hollywood, Florida
Conditions: Ductus Arteriosus, Patent
A Study of DS-9606a in Patients With Advanced Solid Tumors
Recruiting
This study will assess the safety and tolerability of DS-9606a in patients with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Florida Cancer Specialists & Research Institute, LLC, Fort Myers, Florida
Conditions: Advanced Cancer, Metastatic Cancer, Ovarian Cancer, Germ Cell Tumor
Tracking Results of Ablations to Combat AF Registry Generation 2
Recruiting
The primary objective of the TRAC-AF Registry is to capture real-world safety and effectiveness data on AtriCure devices used to conduct concomitant open heart and/or hybrid ablation, and management of the Left Atrial Appendage concomitant to a cardiac ablation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Delray Medical Center, Delray Beach, Florida
Conditions: Atrial Fibrillation
Inappropriate Sinus Tachycardia Registry
Recruiting
The primary objective of this registry is to capture real-world safety and performance data on AtriCure devices used to ablate cardiac tissue when treating Inappropriate Sinus Tachycardia (IST) or Postural Tachycardia Syndrome (POTS). This is a retrospective and prospective, multicenter, US/OUS, observational data registry.
Gender:
ALL
Ages:
All
Trial Updated:
03/25/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome
American Lung Association (ALA) Lung Health Cohort
Recruiting
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
Gender:
ALL
Ages:
Between 25 years and 35 years
Trial Updated:
03/25/2025
Locations: Nemours Children's Jacksonville, Jacksonville, Florida
Conditions: Lung Diseases