Florida is currently home to 3843 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Efficacy of a Breathwork Practice (SKY) on Well-Being of Individuals With Parkinson's Disease (iPD) and Care Partners
Recruiting
The goal of this feasibility study and clinical trial is to learn if an evidenced-based breathwork and meditation intervention (SKY Breath) will improve the mental and physical well-being of individuals with Parkinson's Disease (iPD) in stages 1, 2, and 3, under the age of 75 and their care partners. The main questions it aims to answer are: * Objective 1: Can the SKY Breath practice be designed and implemented to specifically cater to the unique needs of individuals with Parkinson's Disease an... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/24/2025
Locations: Raw Kickboxing and Fitness, Coral Springs, Florida
Conditions: Parkinson's Disease
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
Recruiting
The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to inform CF research, help design CF clinical trials and support the development of new treatments for people with CF who do not take CFTR modulators. Another goal of this study is to learn about research... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/24/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Cystic Fibrosis
Digital Dyadic Family Based Intervention to Improve Sleep in Children with ODD and Their Parents: NiteCAPP SINCC (Pilot)
Recruiting
In this proposal a brief web-based cognitive behavioral treatment for insomnia (CBT-I) for children with oppositional defiant disorder (ODD) and their parents is iteratively adapted and tested for acceptability, feasibility, and preliminary efficacy.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
03/24/2025
Locations: University of South Florida, Tampa, Florida
Conditions: Oppositional Defiant Disorder, Insomnia Chronic
SLEEP-COPE: Sleep Intervention for Oppositional Children
Recruiting
Children with Oppositional Defiant Disorder (ODD) are at risk for insomnia, arousal dysfunction, mood problems, and noncompliance. Cognitive behavioral treatment for insomnia (CBT-I) holds promise for improving insomnia and related concerns. Telehealth delivery will reduce the burden of in-person sessions, particularly in areas where there is low mental healthcare access. Telehealth CBT-I is efficacious in adults and children but has not been tested in children with ODD. The proposed trial is th... Read More
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
03/24/2025
Locations: University of South Florida, Tampa, Florida
Conditions: Insomnia Chronic, Oppositional Defiant Disorder
UCF Deciding Brains
Recruiting
The purpose of this research study is to understand how people make trust-related decisions in healthy aging. Participants will be asked to complete one study session on the University of Central Florida (UCF) campus. The study session will be conducted in a private testing room and include a series of computerized cognitive tasks and learning games, as well as surveys of your beliefs, preferences, and past experiences. The study will take a total of approximately 3.5 hours to completed. You w... Read More
Gender:
ALL
Ages:
20 years and above
Trial Updated:
03/24/2025
Locations: University of Central Florida, Orlando, Florida
Conditions: Trust
Study of RMC-6291 in Combination with RMC-6236 in Participants with Advanced KRAS G12C Mutant Solid Tumors
Recruiting
This study is to evaluate the safety, tolerability, and PK profiles of RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors.
Gender:
ALL
Ages:
Between 18 years and 125 years
Trial Updated:
03/24/2025
Locations: Florida Cancer Specialists, Sarasota, Florida
Conditions: Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer, Pancreatic Ductal Adenocarcinoma
Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA
Recruiting
The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).
Gender:
ALL
Ages:
Between 28 days and 17 years
Trial Updated:
03/24/2025
Locations: Omeros Investigational Site, Gainesville, Florida
Conditions: Thrombotic Microangiopathies, Hematopoietic Stem Cell Transplantation
Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)
Recruiting
The primary purpose of this research study is to evaluate the safety and possible harms of injecting one's own Schwann cells along with nerve auto-graft after a severe injury to a major nerve has occurred.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/24/2025
Locations: University of Miami, Miami, Florida
Conditions: Peripheral Nerve Injury
A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
Recruiting
The primary objectives of Cohort A Phase 1b are to evaluate the safety and tolerability of TTI-101 orally administered as a single agent to participants with locally advanced or metastatic, and unresectable Hepatocellular Carcinoma (HCC) and to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of TTI-101 as a single agent. The primary objectives of Cohort A Phase 2 are to evaluate the safety and tolerability of TTI-101 orally administered as a single agent at the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Hepatocellular Carcinoma
Study of INCB123667 in Subjects With Advanced Solid Tumors
Recruiting
This is an open-label, dose-escalation and dose-expansion study to determine the safety, tolerability, PK, pharmacodynamics, and preliminary efficacy of INCB123667 when administered as monotherapy and in combination with anticancer therapies in participants with selected advanced or metastatic solid tumors. This study will consist of 2 parts. In Part 1, INCB123667 will be administered as monotherapy and in Part 2, INCB123667 will be administered in combination with anticancer therapies of intere... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Mount Sinai Medical Center Comprehensive Cancer Center, Miami Beach, Florida
Conditions: Solid Tumors
In-Utero Endoscopic Correction of Spina Bifida
Recruiting
The purpose of this study is to evaluate the feasibility and effectiveness of performing fetoscopic surgical correction of fetal spina bifida. Two surgical approaches will be utilized: the percutaneous technique versus the laparotomy/uterine exteriorization technique.
Gender:
FEMALE
Ages:
Between 18 years and 52 years
Trial Updated:
03/24/2025
Locations: Wellington Regional Medical Center, Wellington, Florida
Conditions: Neural Tube Defects, Spina Bifida, Myelomeningocele
Go Fit Fast, Recovery Trajectory Using PROMISĀ®, Linking PROMISĀ®
Recruiting
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment. Data collection will include underlying disease, treatment details, patient reported outcomes (PROs), anticipated or procedure-related adverse events (i.e. complications), and radiological outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of Miami, Jackson Memorial Hospital Ryder Trauma Center, Miami, Florida
Conditions: Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal, Distal Radius Fracture