Florida is currently home to 3843 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
Recruiting
This study will assess the safety and effectiveness of GORE® CARDIOFORM Septal Occluder in a post approval setting and evaluate the quality of operator education and training and transferability of trial experience to a post-market setting.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/24/2025
Locations: Naples Community Hospital, Naples, Florida
Conditions: Stroke, PFO - Patent Foramen Ovale
Short Course Radiotherapy for the Treatment of Patients with Glioblastoma, SAGA Study
Recruiting
This phase II trial compares the effect of short course radiotherapy (RT) to standard course RT for the treatment of patients diagnosed with glioblastoma (GBM). The researchers want to learn whether the shorter course treatment is non-inferior (not worse than the standard of care), for patients with GBM. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Short course radiotherapy delivers higher doses of radiation over a shorter per... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/23/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Glioblastoma
A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)
Recruiting
ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2025
Locations: AnaptysBio Investigational Site 10-127, Brooksville, Florida
Conditions: Ulcerative Colitis
Early Feasibility Study of the Velocity™ Percutaneous Arterio-Venous Fistula System for Creating Hemodialysis Vascular Access
Recruiting
The Velocity Percutaneous Arterio-Venous System is a minimally invasive method of creating hemodialysis vascular access. The study aims to understand clinical efficacy and initial clinical safety data of the device.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/21/2025
Locations: American Access Care of Jacksonville, Jacksonville, Florida
Conditions: Chronic Kidney Disease Requiring Hemodialysis, End Stage Renal Disease (ESRD)
Prophylaxis Guided by Cytomegalovirus-specific T Cell Immunity to Prevent Cytomegalovirus Disease in Lung Transplant Recipients
Recruiting
The purpose of this study is to evaluate the clinical outcomes of Cytomegalovirus (CMV) virus in the participants' body. Therefore, the study team will follow the participants' immunological response based on the Cytomegalovirus (CMV) virus testing.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/21/2025
Locations: University of Miami, Miami, Florida
Conditions: Lung Diseases
Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis
Recruiting
The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.
Gender:
ALL
Ages:
Between 30 years and 55 years
Trial Updated:
03/21/2025
Locations: The University of South Florida Board of Trustees, Tampa, Florida
Conditions: Sensorineural Hearing Loss, Bilateral
HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma
Recruiting
The study will evaluate the safety and effectiveness of a lower than standard dose of radiation for definitive or adjuvant treatment of head and neck squamous cell carcinomas.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Squamous Cell Carcinoma of the Oropharynx
Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment
Recruiting
This study will use multiple methods to assess the feasibility of conducting a fully powered multisite clinical trial to test the effectiveness of integrating mindfulness-based interventions into physical therapy for patients with chronic musculoskeletal pain and long-term opioid treatment. First, researchers will develop a manual for training physical therapists to provide mindfulness-based interventions to patients with chronic musculoskeletal pain and long-term opioid treatment. Next, the re... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/21/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Chronic Pain, Pain, Musculoskeletal, Opioid Use, Physical Therapy
A Study of Virtual Reality and Linaclotide for IBS-C
Recruiting
The purpose of this study is to determine if adult patients with IBS-C will report an overall greater improvement in IBS symptoms and quality of life when treated with a combination of linaclotide (standard of care medication) and immersive virtual reality (VR) therapy compared to those treated with linaclotide and sham (placebo) VR therapy.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Irritable Bowel Syndrome With Constipation
CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Recruiting
CB010A is a study evaluating safety, emerging efficacy, pharmacokinetics and immunogenicity of CB-010 in adults with relapsed/refractory B cell non-Hodgkin lymphoma after lymphodepletion consisting of cyclophosphamide and fludarabine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Advent Health, Orlando, Florida
Conditions: Lymphoma, Non-Hodgkin, Relapsed Non Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Non Hodgkin Lymphoma, Lymphoma, B Cell Lymphoma, B Cell Non-Hodgkin's Lymphoma
Telehealth-Delivered Gut-Directed Hypnotherapy for Managing GI Health
Recruiting
This study aims to evaluate the specific and non-specific effects of hypnotherapy and to evaluate the efficacy of group-format gut-directed hypnotherapy (GDH) delivered via telehealth for managing gastrointestinal health.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/20/2025
Locations: University of Central Florida, Orlando, Florida
Conditions: Gastrointestinal Disease, Gastrointestinal Disorders, Nervous System
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Subjects With Refractory Generalized Myasthenia Gravis
Recruiting
A Study of the Anti-CD 19 Chimeric Antigen Receptor T Cell Therapy for Subjects with Myasthenia Gravis
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/20/2025
Locations: University of Miami, Miami, Florida
Conditions: Myasthenia Gravis, Generalized Myasthenia Gravis