Florida is currently home to 3831 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics
Recruiting
To determine if decreased production or release of endogenous opioid peptides by peripheral immune cells contributes to hypersensitivity in people with HIV
Gender:
ALL
Ages:
Between 19 years and 65 years
Trial Updated:
02/15/2025
Locations: Ambulatory Care Center, Florida International University, Miami, Florida
Conditions: Chronic Widespread Pain
Effects of Metabolic Testing Data and Education on Attitudes and Beliefs Related to Carbohydrate Intake in Adolescent Female Athletes
Recruiting
Many studies have consistently shown that females across sports under consume carbohydrate. Registered dietitians working with athletes have also reported female athletes chronically under consume carbohydrate. The primary objective of this study is to compare the effectiveness of education versus education plus interpreted individual metabolic (exercise) testing results to change attitudes and beliefs of female athletes regarding carbohydrate intake. The secondary objective is to assess the eff... Read More
Gender:
FEMALE
Ages:
Between 13 years and 19 years
Trial Updated:
02/14/2025
Locations: Gatorade Sports Science Institute at IMG Academy, Bradenton, Florida
Conditions: Nutritional Deficiency
The Effect of Vicia Faba Hydrolysate Supplementation on Muscle Strength Recovery
Recruiting
To investigate the effect of Vicia faba protein concentrate, a protein derived from Fava bean extract, on delayed onset muscle soreness (DOMS). Participants receive either 2.4g/day of PeptiStrong® supplement capsules or placebo capsules for 14 days until a strenuous exercise session. For the last 3 days, 2/3 of them stay on the same treatment and 1/3 of them switch from placebo to PeptiStrong®.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
02/14/2025
Locations: Gatorade Sports Science Institute at IMG Academy, Bradenton, Florida
Conditions: Muscle Damage, Muscle
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
Recruiting
This study is being done to find out if patient blood samples can be used to perform individualized modeling of cancer therapy-related side effects.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
Recruiting
This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors with particular focus on Colorectal carcinoma (CRC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Florida Cancer Specialists & Research Institute, Sarasota, Florida
Conditions: Colorectal Cancer, Cholangiocarcinoma, Appendiceal Adenocarcinoma, Pancreatic Adenocarcinoma, Gastric Adenocarcinoma, Endometrial Adenocarcinoma, Triple Negative Breast Cancer, Ovarian Cancer, Prostate Cancer
Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women
Recruiting
This study evaluates whether adding a polygenic risk score evaluation to standard breast cancer risk assessment tools helps African American and Hispanic women make more informed decisions about accepting additional breast cancer screening and prevention strategies. Traditional breast cancer risk assessments rely mostly on the presence of standard clinical risk factors including family history, reproductive history, and mammographic breast density. This information can be combined with validated... Read More
Gender:
FEMALE
Ages:
Between 30 years and 75 years
Trial Updated:
02/14/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Atypical Ductal Hyperplasia, Breast Atypical Lobular Hyperplasia, Breast Carcinoma, Breast Lobular Carcinoma In Situ
Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study
Recruiting
This clinical trial studies how well intensity modulated proton therapy (IMPT) or intensity modulated X-ray (radiation) therapy (IMRT) works after surgery in treating patients with head and neck cancer. IMPT is a type of radiation therapy that allows for the most accurate application of proton radiation to the tumor and has the potential to reduce treatment-related side effects. IMRT is a type of 3-dimensional radiation therapy that uses computer-generated images to show the size and shape of th... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Head and Neck Carcinoma, Head and Neck Carcinoma of Unknown Primary, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Metastatic Malignant Neoplasm in the Lymph Nodes, Nasal Cavity Carcinoma, Oral Cavity Carcinoma, Oropharyngeal Carcinoma, Paranasal Sinus Carcinoma, Salivary Gland Carcinoma, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck
Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
Recruiting
Researchers are trying to identify predictors for gastroesophageal reflux disease after sleeve gastrectomy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Orlando Health, Orlando, Florida
Conditions: Gastroesophageal Reflux, Sleeve Gastrectomy, Bariatric Surgery Complication
Evaluation of a Brief, Scalable Module to Mitigate Suicidal Ideation Among Youth
Recruiting
This project is designed to test a brief therapy to reduce suicidal ideation among a diverse sample of youths ages 12 to 17 who experience anxiety or depression. The goal of the study is to conduct a clinical trial testing whether this therapy reduces suicidal ideation and related beliefs that one is a burden on others. This project will contribute to the field by potentially showing evidence supportive of a brief strategy to reduce suicidal ideation in a way that can be readily understood and u... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
02/13/2025
Locations: FIU Center for Children and Families, Miami, Florida
Conditions: Suicidal Ideation
A Trial Investigating Lu AG09222 With Ubrogepant in Participants With Migraine
Recruiting
The main goal of this trial is to learn more about the safety and tolerability of Lu AG09222 when taken together with ubrogepant. This includes looking for any new or worsening medical issues the participants have with the treatment. During the trial, participants with migraine will receive ubrogepant oral tablets and an injection of either Lu AG09222 or a placebo.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/13/2025
Locations: Clinical Neuroscience Solutions, Orlando, Florida
Conditions: Migraine
REBYOTA™ Prospective Registry
Recruiting
This is a prospective observational cohort study designed to collect data on patients who received REBYOTA™ for the prevention of rCDI in the routine care setting. As all data collected for this study are observational, the decision to prescribe REBYOTA™ is at the treating physician's discretion and independent from the decision to enroll the patient in the study. Data will be collected from patients' medical records after obtaining informed consent. Data about clinical history, CDI events (prim... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: Ferring Investigational Site, Gainesville, Florida
Conditions: Recurrence of Clostridium Difficile Infection
Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma
Recruiting
The purpose of this research is to determine whether the combination of selinexor, venetoclax, and dexamethasone therapy can increase anti-cancer effects in patients with translocation 11;14-positive (t(11;14)), relapsed/refractory myeloma (RRMM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: University of Miami, Lennar Foundation Medical Center, Coral Gables, Florida
Conditions: Relapsed and Refractory Multiple Myeloma