Florida is currently home to 3831 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Feasibility of the Pray Until Something Happens (PUSH) Intervention-OUTPATIENT
Recruiting
The goal of this research study is to reduce stress and improve sickle cell disease (SCD) pain control and sleep quality with less opioid use by determining the feasibility of an intervention with self-management combined intercessory and petitionary prayer, named Pray Until Something Happens (PUSH) stress reduction intervention using a mobile smart device. Currently, opioid analgesics are primarily used to treat SCD pain while self-managed behavioral modalities such as PUSH, are rarely used. Li... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
01/24/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Sickle Cell Disease, Stress, Pain
Using Transcriptional Assessment of Immune Response to Assess Immunosuppression After Liver Transplantation
Recruiting
To develop a prospective quantitative liver allograft monitoring protocol and retrospectively validate the use of Phenotypic personalized medicine (PPM) in immunosuppression dosing in liver transplant recipients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/24/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Transplant Complication
LASER Pilot Project
Recruiting
Veterans who use prosthetic limbs commonly suffer from skin problems such as scars that create discomfort and pain to the point that wearing the prosthesis is no longer tolerable. The Veteran must then discontinue prosthetic use to allow healing prior to wearing the limb again. Current treatments for skin problems include manual scar mobilization and massage, stretching, desensitization techniques, pain medication, prosthetic adjustment, steroid injection, scar excision and others. Most of these... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
01/24/2025
Locations: Miami VA Healthcare System, Miami, FL, Miami, Florida
Conditions: Acquired Absence of Lower Limb, Scar Condition and Fibrosis of the Skin
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
Recruiting
This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal anti-inflammatory drug. Giving low-dose aspirin may affect markers of inflammation in blood and tissue and may prevent postpartum related breast cancer.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/24/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Carcinoma
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
Recruiting
This phase Ib trial studies the side effects and best dose of a vaccine called H2NVAC before surgery in treating patients with HER2 expressing ductal carcinoma in situ. H2NVAC is a vaccine designed to stimulate specialized white blood cells in hopes of increasing immune response and protecting against breast cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Ductal Carcinoma In Situ
Non-invasive Glioma Characterization Through Molecular Imaging
Recruiting
MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: University of Miami, Miami, Florida
Conditions: Glioma, Brain Tumor, Primary Brain Tumor, Malignant Glioma, Malignant Primary Brain Tumor
Long Term Surveillance of Islet Transplant Recipients Following Complete Graft Loss
Recruiting
This is a single-center, prospective, open label study in islet transplant recipients following islet graft loss.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/24/2025
Locations: Diabetes Research Institute, Miami, Florida
Conditions: Type 1 Diabetes Mellitus
Long Term Follow up of Recipients of Functional Islet Allografts
Recruiting
Since its inception, the Diabetes Research Institute (DRI) has made significant contributions to the field of diabetes, pioneering many of the techniques used in diabetes centers around the world. Through several clinical trials, DRI has demonstrated that diabetes can be successfully reversed as a result of islet cell transplant. Over the years the following protocols in islet cell transplantation have been initiated: 2000/0329; 2000/0196; 2004/0205; 2000/024; 2006/0200; 2006/0508; 2006/0210.... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/24/2025
Locations: Diabetes Research Institute, Miami, Florida
Conditions: Type 1 Diabetes Mellitus
Prevention of de Novo Allosensitization in Islet Transplant Recipients Following Complete Graft Loss
Recruiting
This is a single-center, prospective, open label study in islet transplant recipients after complete islet graft rejection/loss, defined as stimulated c-peptide ≤0.3 ng/mL.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/24/2025
Locations: Diabetes Research Institute, Miami, Florida
Conditions: Type 1 Diabetes Mellitus
Collecting Medical Information and Tissue Samples from Patients with Pancreatic Cancer or Other Pancreatic Disorders
Recruiting
RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic disorders in the future. PURPOSE: This clinical trial is collecting medical information and tissue samples from patients with pancreatic cancer or other pancreatic disorders.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Islet Cell Tumor, Pancreatic Cancer, Pancreatic Disease, Acute Pancreatitis, Chronic Pancreatitis, Hereditary Pancreatitis, Pancreatic Neuroendocrine Carcinoma
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
Recruiting
In this first-in human, phase I/IIa study, the safety and efficacy of \[212Pb\]VMT01, an alpha-particle emitting therapeutic agent targeted to melanocortin sub-type 1 receptor (MC1R) is being evaluated as a monotherapy and in combination with Nivolumab in subjects with unresectable and metastatic melanoma.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/23/2025
Locations: Biogenix Molecular, Miami, Florida
Conditions: Melanoma (Skin), Metastatic Melanoma, Melanoma Stage IV, Mucosal Melanoma, Melanoma Stage III
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters
Recruiting
Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 65 years of age.
Gender:
MALE
Ages:
Between 22 years and 65 years
Trial Updated:
01/23/2025
Locations: Orlando Health, Orlando, Florida
Conditions: Urethral Stricture