Florida is currently home to 3765 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST
Recruiting
The purpose of this research is to test if mutations (changes in DNA) in exons (segment of DNA or RNA containing information that has the instructions for making proteins) in the KIT gene can be used to predict the body's response to standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2024
Locations: University of Miami, Miami, Florida
Conditions: Gastrointestinal Stromal Tumors
Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD
Recruiting
The purpose of this study is to examine the benefits of combining repetitive Transcranial Magnetic Stimulation (rTMS) coupled with Cognitive Processing Therapy (CPT) in treating combat-related Posttraumatic Stress Disorder (PTSD) symptoms. The study will also examine change in depression, psychosocial functioning, and neurophysiological (i.e., electroencephalography and magnetic resonance images) measures.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
10/23/2024
Locations: Florida State University College of Medicine, Tallahassee, Florida
Conditions: Post Traumatic Stress Disorder
ALTO-100 in Bipolar Disorder with Depression (BD-D)
Recruiting
The purpose of this study is to assess antidepressant efficacy differences between ALTO-100 and placebo during the Double-Blind period in patients with bipolar disorder I or II with current major depressive episode, when used adjunctively to a mood stabilizer, related to patient characteristics. Additionally, safety, tolerability, and efficacy will be assessed in a subsequent open label treatment period.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/22/2024
Locations: Site 6067, Lauderhill, Florida
Conditions: Bipolar Disorder I or II with a Major Depressive Episode
PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence
Recruiting
Flotufolastat F-18, sold under the brand name Posluma, is a radioactive diagnostic agent for use with positron emission tomography (PET) imaging for prostate cancer. The research is being done to study the capability of 18F-rhPSMA-7.3 (flotufolastat F-18) PET scan to detect prostate cancer when there are very low levels of Prostate-Specific Antigen (PSA) following previous radical prostatectomy surgery.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/22/2024
Locations: AdventHealth, Orlando, Florida
Conditions: Prostate Cancer (Post Prostatectomy)
CARE: Cancer Risk Perception and Women of Color
Recruiting
This study examines patient understanding of current and lifetime risk for breast cancer in women of color from diverse racial and ethnic backgrounds.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
10/22/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Carcinoma
HIIT Following Breast Cancer Chemotherapy
Recruiting
Chemotherapy is an effective breast cancer treatment, which helped to increase the 5-year survival rate to approximately 95%. However, breast cancer survivors have a higher risk of cardiovascular disease (CVD) due to chemotherapy than adults without cancer. Cardiovascular rehabilitation can be an effective strategy to decrease the incidence of CVD and its risk factors in this population. The proposed study may help to examine the effect and durability of a novel high-intensity interval training... Read More
Gender:
FEMALE
Ages:
Between 18 years and 85 years
Trial Updated:
10/22/2024
Locations: Integrative Cardiovascular Physiology Laboratory, University of Florida, Gainesville, Florida
Conditions: Breast Cancer
Efficacy of Education Versus Education Plus Prescribed Fluid Intake on Hydration Status in High School Athletes
Recruiting
Sports science testing by investigators at Gatorade Sports Science Institute has revealed that many athletes arrive at practice with a high urine specific gravity indicating they are hypohydrated. Though the data showed that most athletes don't lose more than 2% of their body weight in sweat during a training session, it is not known what the cumulative effects of living and training in a hot environment are over the course of a week. Previous research has indicated that prescribing fluid intake... Read More
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
10/21/2024
Locations: Gatorade Sports Science Institute (GSSI) at IMG Sports Academy, Bradenton, Florida
Conditions: Dehydration
Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a diagnosis of Parkinson's Disease consistent with the UK Parkinson's Disease Society (UKPDS) Brain Bank diagnostic criteria, who are experiencing wearing off symptoms and levodopa-induced dyskinesia.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/21/2024
Locations: Clinical Site, Altamonte Springs, Florida
Conditions: Parkinson Disease
Administration of Allogeneic-MSC in Patients with Non-Ischemic Dilated Cardiomyopathy
Recruiting
The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called human allogeneic mesenchymal stem cell therapy.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/21/2024
Locations: University of Miami Miller School of Medicine, Miami, Florida
Conditions: Non-ischemic Dilated Cardiomyopathy
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Recruiting
Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is a unique Registry-Randomized Clinical Trial (RRCT) that will test the hypothesis that spironolactone plus standard of care compared to standard of care alone reduc... Read More
Gender:
ALL
Ages:
Between 50 years and 99 years
Trial Updated:
10/21/2024
Locations: Holy Cross Hospital, Fort Lauderdale, Florida
Conditions: Heart Failure With Preserved Ejection Fraction
Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
Recruiting
The purpose of this study is to look at how Alpha-1-antitrypsin (AAT) deficiency and Cystic Fibrosis (CF) affect white blood cells in the lungs, called macrophages, and their ability to work.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/21/2024
Locations: Shands at the University of Florida, Gainesville, Florida
Conditions: Alpha-1 Antitrypsin Deficiency, AAT Deficiency, AATD, Cystic Fibrosis (CF)
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study
Recruiting
The Alpha-1 Coded Testing (ACT) Study was established to study genetic testing and outcomes of individuals at risk for alpha-1 antitrypsin deficiency.
Gender:
ALL
Ages:
All
Trial Updated:
10/21/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Alpha-1 Antitrypsin Deficiency