Florida is currently home to 3751 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/14/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia, Rheumatoid Arthritis
TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children
Recruiting
This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is safe and effective to treat the patient's underlying condition. This study will use stem cells obtained via peripheral blood or bone marrow from parent or other half-matched family member donor. These will be processed through a special device called CliniMACS, which is considered investigational.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
06/14/2024
Locations: Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Conditions: Primary Immune Deficiency Disorders, Metabolic Disease
TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children
Recruiting
This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is safe and effective to treat the patient's underlying condition. This study will use stem cells obtained via peripheral blood or bone marrow from parent or other half-matched family member donor. These will be processed through a special device called CliniMACS, which is considered investigational.
Gender:
ALL
Ages:
Between 0 years and 21 years
Trial Updated:
06/14/2024
Locations: Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Conditions: Hemoglobinopathy (Disorder), Severe Aplastic Anemia, Bone Marrow Failure Syndrome
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: Bay Pines VA, Bay Pines, Florida
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
Recruiting
This study evaluates the safety and effectiveness of the da Vinci Surgical Systems in prophylactic Nipple Sparing Mastectomy procedures.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/14/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Nipple Sparing Mastectomy
Multi-center Evaluation of the Clinical Utility of ESD in the Western Population
Recruiting
The aim of this multi-center study is to prospectively document the clinical utility of ESD.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/14/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Endoscopic Submucosal Dissection
Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer
Recruiting
This is an open label study to determine the safety and preliminary evidence of a therapeutic effect of azeliragon in patients refractory to prior treatment of metastatic pancreatic cancer.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/13/2024
Locations: Boca Raton Regional Hospital, Lynn Cancer Institute, Boca Raton, Florida
Conditions: Metastatic Pancreatic Cancer
Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma
Recruiting
The purpose of this research study is to see if loncastuximab tesirine has any benefits at dose levels researchers found acceptable in earlier studies in patients with related forms of immune cell cancers. The researchers want to find out the effects (good and bad) that loncastuximab tesirine has on the participant and the participant's condition.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: University of Miami, Miami, Florida
Conditions: Marginal Zone Lymphoma
Multi-analyte Blood Test Clinical Trial
Recruiting
The objective of this study is the acquisition of whole blood samples and serum samples from participants with untreated Hepatocellular Carcinoma (HCC) and subjects undergoing Hepatocellular Carcinoma (HCC) surveillance. These samples will be used for research purposes to develop and validate the Helio multi-analyte blood test.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: Guardian Angel Research Center, Tampa, Florida
Conditions: Liver Cirrhosis, Liver Cancer, HCC, Hepatocellular Carcinoma
A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma
Recruiting
This study is being done to find out whether carfilzomib, lenalidomide, and dexamethasone (KRD) or KRD and Daratumumab (KRD+DARA) might be safer and more effective ways of controlling multiple myeloma than the stand or care treatment, which is lenalidomide, bortezomib, and dexamethasone (VRD).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/13/2024
Locations: University of Miami, Miami, Florida
Conditions: Multiple Myeloma
Treatment of Calcific Total Occlusions in Peripheral Artery Disease
Recruiting
Prospective, multi-center, non-randomized, open label, clinical study intended to provide data to demonstrate safety and performance of the SoundBite Crossing System XS Peripheral.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
06/12/2024
Locations: Palm Vascular Centers, Fort Lauderdale, Florida
Conditions: Chronic Total Occlusion of Artery of the Extremities
Safety and Effectiveness of the PXL-Platinum 330 System for Cornea Crosslinking in Eyes With Cornea Thinning
Recruiting
This study study is to determine the effectiveness of cornea cross linking in patients with Keratoconus or other cornea thinning conditions.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2024
Locations: Cohen Laser and Vision Center, Boca Raton, Florida
Conditions: Keratoconus