Florida is currently home to 3848 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Phase 3 Study to Evaluate the Safety and Tolerability of L606 in Subjects With PAH or PH-ILD
Recruiting
This Phase 3, 2-part, open-label, multicenter study aims to demonstrate the safety and tolerability of L606 in patients with PAH or PH-ILD. The study will determine the short-term and long-term safety and tolerability of L606 in this patient population; also evaluate the steady-state pharmacokinetics (PK) of L606 as compared to Tyvaso, effects on exercise ability, quality of life, and treatment satisfaction with L606.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/09/2023
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Pulmonary Arterial Hypertension, Pulmonary Hypertension Due to Lung Diseases
Digital Rehabilitation Environment Augmenting Medical System
Recruiting
D.R.E.A.M.S. will assess an immersive digital reality-augmenting system in reducing the occurrence of cognitive, behavioral, and emotional consequences of critical illness and environmental exposures that are risk factors for the development of delirium.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/09/2023
Locations: UF Health, Gainesville, Florida
Conditions: Delirium
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
Recruiting
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
Gender:
All
Ages:
Between 6 years and 18 years
Trial Updated:
08/09/2023
Locations: Bausch Site 002, Miami, Florida
Conditions: Psoriasis
Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning
Recruiting
The purpose of this study is to determine the magnitude of clinical benefit achieved through machine learning assisted radiation treatment planning (MLAP) on post-treatment clinical outcomes such as acute toxicity and patient reported outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/08/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Cancer Head Neck, Cancer, Head, Cancer Neck
Natural History of Wilson Disease
Recruiting
The purpose of the registry/repository is to provide a mechanism to store data and specimens to support the conduct of future research about Wilson disease (WD). The overall aim is to determine the optimal testing for diagnosis and parameters for monitoring treatment of WD that will aid product utilization and development.
Gender:
All
Ages:
All
Trial Updated:
08/08/2023
Locations: Advent Health, Orlando, Florida
Conditions: Wilson Disease
Lactobacillus Johnsonii in Children and Adolescents With T1D
Recruiting
While genetics demonstrated a major risk factor for the development of type 1 diabetes (T1D), microbiota dysbiosis has been suggested as an elicitor in immunological tolerance and of beta cell autoimmunity. The probiotic Lactobacillus johnsonii N6.2 may prevent or restore the gut flora and show systemic impacts and adaptive immunity in the T1D population thereby preserving beta cell function.
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
08/07/2023
Locations: UF Clinical Research Center, Gainesville, Florida
Conditions: Type 1 Diabetes (T1D)
Lactobacillus Johnsonii Supplementation in Adults With T1D
Recruiting
While genetics demonstrated a major risk factor for the development of type 1 diabetes (T1D), microbiota dysbiosis has been suggested as an elicitor in immunological tolerance and of beta cell autoimmunity. The probiotic Lactobacillus johnsonii N6.2 may prevent or restore the gut flora and show systemic impacts and adaptive immunity in the T1D population thereby preserving beta cell function.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
08/07/2023
Locations: UF Clinical Research Center, Gainesville, Florida
Conditions: Type 1 Diabetes (T1D)
The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
Recruiting
The goal of treating patients diagnosed with rheumatoid arthritis (RA) is to achieve remission or low disease activity and thereby prevent joint damage, loss of physical function, and disability. Optimal management requires regular assessment of disease activity, with treatment changes made as needed for optimal efficacy. Vectra is a blood serum test that looks at 12 biomarkers and produces a score on a scale of 1 to 100. The Vectra score has been shown to be the strongest predictor of risk for... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: AARDS Research, Inc., Aventura, Florida
Conditions: Rheumatoid Arthritis (RA)
Single and Combined Effects of Behavioral, Academic, and Medication Treatments for ADHD in the Classroom
Recruiting
This study is the first to systematically evaluate the efficacy of single and combined academic accommodation, behavioral treatment, and medication treatment in a large sample of children with ADHD. Using a scientifically rigorous, cross-over design the impact of these approaches on ecologically valid measures of outcome (on-task behavior, quiz scores, academic productivity) will be assessed to inform effective school intervention.
Gender:
All
Ages:
Between 5 years and 12 years
Trial Updated:
08/03/2023
Locations: FIU Center for Childern and Families, Miami, Florida
Conditions: ADHD
Stellate Ganglion Block for PTSD
Recruiting
Posttraumatic Stress Disorder (PTSD) is a debilitating condition that affects about 15% of Veterans. Current treatments for Veterans with PTSD include medications and psychological therapies that help to process and desensitize to traumatic events. While effective for many, these treatments do not work for all patients, and many may refuse them. Stellate Ganglion Block (SGB), established to treat pain and other conditions, has shown promise for PTSD: early small studies show it may work fast and... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/03/2023
Locations: James A. Haley Veterans' Hospital, Tampa, FL, Tampa, Florida
Conditions: Post-traumatic Stress Disorder
Fluorescence Imaging of Carcinoma During Breast Conserving Surgery
Recruiting
Breast conserving surgery (BCS) is performed on patients with breast cancer to resect and completely remove the cancer while conserving as much of the surrounding healthy tissue as possible. Current methods do not allow surgeons to determine the completeness of surgical resection in real-time. This often results in the need for a second surgical procedure, or in some cases more than two surgical procedures in order to have confidence that all cancer has been removed. This Phase 3 study will eva... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: Orlando Health, Inc., Orlando, Florida
Conditions: Breast Neoplasm Female, Breast Cancer
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome
Recruiting
The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.
Gender:
All
Ages:
Between 44 weeks and 17 years
Trial Updated:
08/03/2023
Locations: Variety Children's Hospital D/B/A Nicklaus Children's Hospital, Miami, Florida
Conditions: Acute Respiratory Distress Syndrome