Florida is currently home to 3831 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Amyotrophic Lateral Sclerosis
A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants with Generalized Anxiety Disorder (GAD)
Recruiting
The purpose of this proof-of-concept trial is to examine the safety, tolerability, and pharmacokinetics (PK), and preliminary clinical efficacy of CYB004 participants with GAD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/08/2024
Locations: Innovative Clinical Research, Inc., Miami Lakes, Florida
Conditions: Generalized Anxiety Disorder
Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain
Recruiting
The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/08/2024
Locations: University of Miami, Miami, Florida
Conditions: Spinal Cord Injuries, Neuropathic Pain
Proteinuria in Pre and Post Transplant
Recruiting
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.
Gender:
ALL
Ages:
25 years and below
Trial Updated:
10/08/2024
Locations: University of Miami Miller School of Medicine Transplant Clinic, Miami, Florida
Conditions: Proteinuria
Precise Oncology Interventions in Nutrition and Training (OnPoint)
Recruiting
The purpose of this study is to see if survivors of breast, prostate, or colorectal cancer who receive a personal referral to a targeted nutrition and exercise program will be able to eat a healthier diet and be more physically activity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Miami, Miami, Florida
Conditions: Breast Cancer, Prostate Cancer, Colorectal Cancer
Unified Protocol: Community Connections
Recruiting
The purpose of this study is to administer the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) and Adolescents (UP-A) to youth and participants' parents and to examine the efficacy and outcomes of the treatment using standardized measures, questionnaires, interviews. The UP-C and the UP-A are cognitive-behavioral therapies to treat emotional disorders.
Gender:
ALL
Ages:
Between 7 years and 17 years
Trial Updated:
10/07/2024
Locations: Child and Adolescent Mood and Anxiety Treatment Program, Coral Gables, Florida
Conditions: Mental Health Issue, Anxiety Disorder, Depressive Disorder, Parenting
Mixed-reality REBOA Simulator With Virtual Coaching
Recruiting
Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is a life-saving emergency procedure that is highly suited for simulation-based training. This study aims to assess the validity of our REBOA simulator with virtual coach (or live quantitative feedback) for mastery learning. The hypotheses are: H0: Virtual coach is non-inferior in REBOA training to an average human instructor. H1: Virtual coach is inferior in REBOA training to an average human instructor. We expect to learn wh... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Hemorrhage, Simulation Training
NSAID Use After Robotic Partial Nephrectomy
Recruiting
The purpose of this study is to see how effective non-steroidal anti-inflammatory drugs (NSAIDs) are at controlling pain without side effects in participants after robotic-assisted partial nephrectomy.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
10/04/2024
Locations: University of Miami, Miami, Florida
Conditions: Kidney Cancer, Renal Cancer, Renal Neoplasm
Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients with Inflammatory or Invasive Breast Cancer
Recruiting
This trial studies the biospecimen and medical data collection in creating a research tissue registry in patients with inflammatory or invasive breast cancer. Collecting medical data and storing samples of blood, tissue, and stool from patients with inflammatory breast cancer to study in the laboratory may help doctors find better ways to treat and study inflammatory breast cancer in the future.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: Baptist - MD Anderson Cancer Center, Jacksonville, Florida
Conditions: Inflammatory Breast Carcinoma, Invasive Breast Carcinoma, Second Primary Malignant Neoplasm
A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
Recruiting
This study will assess the efficacy and safety of bilateral intra-parotid administration of AAV2-hAQP1 in adults with Grade 2 or Grade 3 radiation-induced late xerostomia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: Miami Cancer Institute at Baptist Health South Florida, Miami, Florida
Conditions: Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
Evaluating Stress Management Strategies Within the School Readiness Parenting Program
Recruiting
The goal of this randomized study is to learn if adding three additional parent training sessions (focused on alleviating parental stress) to an already well-established treatment (School Readiness Parenting Program \[SRPP\]) in improving outcomes up to 6- and 12-months later for families of children with disruptive behavior disorders. The main questions it aims to answer are: The primary objective of this protocol is to evaluate the effects of three additional cognitive behavioral therapy (CBT... Read More
Gender:
ALL
Ages:
Between 4 years and 6 years
Trial Updated:
10/02/2024
Locations: Florida International University, Miami, Florida
Conditions: Parenting, Stress, Disruptive Behavior Disorder, Parent-Child Relations, ADHD
Promoting Playfulness
Recruiting
Health inequalities, social isolation, and family adversity impact a child's development. Play is the context for child development in all areas. A parent's ability to support children at play while being playful contributes to their psychological adjustment. The proposed tier 1, strengths-based educational program for parents of children aged 2 to 5 years with and without disabilities combines elements of a play-based approach and tips on effective parenting to support children's development by... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/02/2024
Locations: Little Eagles Learning Center, Fort Myers, Florida
Conditions: Developmental Delay (Disorder)