Florida is currently home to 3825 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Digital Detection of Dementia (D Cubed) Studies: D3
Recruiting
The specific aim of the pragmatic trial is to evaluate the practical utility and effect of the PDM, the QDRS, and the combined approach (PDM + QDRS) in improving the annual rate of new documented ADRD diagnosis in primary care practices.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
09/11/2024
Locations: University of Miami School of Medicine, Boca Raton, Florida
Conditions: Alzheimer Disease and Related Dementias (ADRD)
Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy
Recruiting
Currently, the standard of care for female patients undergoing radical cystectomy includes the removal of the bladder, pelvic lymph nodes, anterior vagina, uterus, fallopian tubes and ovaries. Removal of female ancillary organs, both in pre and post-menopausal stages is associated with reduction in various quality of life metrics, including sexual health, cognitive decline and depression. Furthermore, removal of ovaries has been associated with increased cardiovascular events, metabolic acidosis... Read More
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
09/11/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Urothelial Carcinoma Bladder
Combined Respiratory Training in Persons with ALS
Recruiting
The goal of this interventional trial is to learn about lung volume recruitment (LVR) and expiratory muscle strength training (EMST) in a total of up to 39 patients diagnosed with ALS. The following aims will be addressed: 1. Determine the impact of combined LVR and EMST on cough strength and respiratory function in individuals with ALS. 2. Determine the impact of combined LVR and EMST on patient-reported dyspnea and bulbar impairment. 3. Describe the effect of combined LVR and EMST on patient-... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
09/11/2024
Locations: Nova Southeastern University, Fort Lauderdale, Florida
Conditions: ALS, Respiratory Insufficiency, Dysphagia
Promising ROd-cone DYstrophy Gene TherapY
Recruiting
This is a two-step, multicenter, Phase I/II study including an open-label dose-escalation phase (Step 1) and a three-arm, controlled, double-masked, randomized extension phase (Step 2), in subjects with advanced RCD due to a mutation in the RHO, PDE6A, or PDE6B gene.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/11/2024
Locations: Bascom Palmer Eye Institute/University of Miami, Miami, Florida
Conditions: Retinitis Pigmentosa
Encore PFO Closure Device - The PerFOrm Trial
Recruiting
The objective of this study is to establish reasonable assurance of safety, effectiveness, and noninferiority of the Encore PFO closure device when compared to any investigator chosen FDA-approved PFO closure device.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
09/11/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Patent Foramen Ovale, Cryptogenic Stroke
Planned Semi-Elective Lung Tx Study
Recruiting
When suitable donor lungs become available for a consented recipient, and the donor cross clamp time occurs between 6pm and 4am, the transplant procedure (anesthesia starting time) will be allowed to be moved to a 6am start or later with the lungs being preserved at 10C cold static preservation upon organ arrival to our hospital using a specific refrigerator. The maximum allowed time between donor cross clamp and recipient anesthesia initiation will be 12h.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
09/11/2024
Locations: UFHealth Shands, Gainesville, Florida
Conditions: To Compare Lung Transplant Outcomes Between Study Patients and Standard Patients Who Have Already Undergone Lung Transplantation by Conventional Procedures, Lung Transplant
FAMILY Sleep Program
Recruiting
The purpose of this study is to learn about sleep behaviors and test different ways to help patients with cancer and partners. Participants (patient-sleep-partner caregivers dyads as a unit) participate in the study together.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Cancer
Suture Repair vs Mesh Repair for Incisional Hernia
Recruiting
The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Incisional Hernia
Artificial Intelligence to Measure Adherence to Oral Medication
Recruiting
The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Citrus Health, Hialeah, Florida
Conditions: First Episode Psychosis
Disengagement in CSC: Identifying Those at Risk and Addressing Their Needs
Recruiting
Maintaining treatment engagement is critical for first episode psychosis patients to experience gains possible with coordinated specialty care (CSC). This study is designed to identify CSC participants still receiving care but at high risk for disengagement and to intervene to prevent/delay disengagement.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Henderson Behavioral Health, Lauderdale Lakes, Florida
Conditions: First Episode Psychosis
Early-Phase Schizophrenia: Practice-based Research to Improve Outcomes
Recruiting
The goal if the project is to develop a learning health network devoted to the treatment of first episode psychosis.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Henderson Behavioral Health, Lauderdale Lakes, Florida
Conditions: First Episode Psychosis
Biomarkers in Friedreich's Ataxia
Recruiting
The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.
Gender:
ALL
Ages:
Between 8 years and 70 years
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Friedreich's Ataxia