Florida is currently home to 3819 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Gastric Ultrasound for Estimation of the Aspiration Risk Study
Recruiting
The purpose of this research study is to look at the effectiveness of current anesthesia guidelines regarding food and drink prior to surgery in patients who are likely to have food and drink remain in their stomach longer than might ordinarily be expected.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/26/2023
Locations: United States, Florida UF Health, Gainesville, Florida
Conditions: Respiratory Aspiration of Gastric Contents
Septorhinoplasty Post-operative Pain Control With SPG Nerve Block
Recruiting
Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery. This randomized, double-blinded, placebo-controlled study will investigate blocks of the pterygopalatine fossa using a suprazygomatic approach during septorhinoplasty surgery. It is the investigator's hypothesis that this technique will result in decreased post-operative pain and opioid use, and the morbidity associated with it.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/25/2023
Locations: UF Health of University of Florida, Gainesville, Florida
Conditions: Deviated Nasal Septum
Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder
Recruiting
The purpose of this research is to compare the efficacy of immediate versus extended-release melatonin as a supplement affecting the sleep cycle in patients with Parkinson disease and Rapid Eye Movement Sleep Behavior Disorder.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Rapid Eye Movement Sleep Behavior Disorder, Parkinson Disease
Treatment of Pruritus With Intramuscular Promethazine
Recruiting
Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery. The aim is to evaluate effectiveness of promethazine (IMP) treatment of intrathecal morphine induced pruritus (ITIMIP). A treatment for ITMIP, other than naloxone, will allow for increased use of intrathecal narcotics and decrease the use of systemic opioids in the initial post-operative period.
Gender:
Female
Ages:
Between 18 years and 99 years
Trial Updated:
05/25/2023
Locations: UF Health at the University of Florida, Gainesville, Florida
Conditions: Pruritus, Pregnancy Related
Vasculitis Pregnancy Registry
Recruiting
The purpose of this study is to learn about the experience of women with vasculitis who become pregnant. In particular, the study will consist of several online surveys to assess each woman's vasculitis severity and pregnancy-related experiences, and pregnancy outcomes.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
05/25/2023
Locations: University of South Florida Data Management and Coordinating Center, Tampa, Florida
Conditions: Vasculitis, Behcet's Disease, CNS Vasculitis, Cryoglobulinemic Vasculitis, Eosinophilic Granulomatosis With Polyangiitis (EGPA), Churg-Strauss Syndrome (CSS), Granulomatosis With Polyangiitis (GPA), Wegener's Granulomatosis, IgA Vasculitis, Henoch-Schoenlein Purpura (HSP), Microscopic Polyangiitis (MPA), Polyarteritis Nodosa (PAN), Takayasu Arteritis (TAK), Urticarial Vasculitis, Systemic Vasculitis
Artificial Intelligence to Measure Adherence to Oral Medication
Recruiting
The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis.
Gender:
All
Ages:
Between 15 years and 40 years
Trial Updated:
05/24/2023
Locations: Citrus Health, Hialeah, Florida
Conditions: First Episode Psychosis
Improve PAD PERformance With METformin
Recruiting
The PERMET trial will determine whether metformin daily for six months improves six-minute walk performance in individuals with peripheral artery disease compared to placebo.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/22/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Peripheral Artery Disease
Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers
Recruiting
In this study, a novel placental membrane product Matrion™ (LifeNet Health, Inc., Virginia Beach, VA) will be used as a treatment for subjects with diabetic foot ulcers. Matrion is composed of placental membrane derived from donated human birth tissue containing both the innermost amniotic layer and the outermost chorionic layer, inclusive of the trophoblast layer. Matrion is minimally processed and disinfected using a proprietary decellularization technology and terminally sterilized that safel... Read More
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
05/19/2023
Locations: Doctors Research Network, Miami, Florida
Conditions: Diabetic Foot, Lower Extremity Wound
NICU Oxygen Control Study
Recruiting
Prematurely born infants in the hospital neonatal intensive care unit (NICU) will be included in the study. This clinical trial is a randomized crossover study to show that our automated oxygen control device performance is no worse than a NICU nurse in keeping a premature neonate's SPO2 within the prescribed range. Since subjects receive the device (automatic oxygen control) and the standard of care (manual control by a nurse), every subject serves as their own perfectly matched control. Perfor... Read More
Gender:
All
Ages:
All
Trial Updated:
05/19/2023
Locations: Studer Family Children's Hospital at Sacred Heart, Pensacola, Florida
Conditions: Hyperoxia, Hypoxia
ProACT Post-Approval Study
Recruiting
The ProACT Post Approval Study is a 5-year prospective, open-label, multi-center study designed to evaluate the long-term incidence of urethral stricture and device erosion after ProACT implantation. In addition, the study will evaluate whether treatment with ProACT affects clinical outcomes after subsequent SUI therapies.
Gender:
Male
Ages:
50 years and above
Trial Updated:
05/19/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Stress Urinary Incontinence
Natesto Spermatogenesis Reboot
Recruiting
This is a prospective, non-blinded study of hypogonadal men with a history of testosterone therapy who became azoospermic or severely oligospermic and wish to avoid symptoms of hypogonadism during their recovery of spermatogenesis in an effort to establish paternity. The study will determine if Natesto can alleviate hypogonadal symptoms while preserving the recovery of spermatogenesis
Gender:
Male
Ages:
Between 18 years and 64 years
Trial Updated:
05/18/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Hypogonadism, Male
A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN
Recruiting
Subjects will be administered multiple doses of VK0214 in a cohort dose escalation process. A total of up to 36 subjects will be enrolled in the study, into one of three dose cohorts. For each cohort, up to 12 subjects will be randomized to receive VK0214 or placebo in a 3:1 ratio so that there will be a total of up to 9 subjects for each of the active doses and up to 3 subjects dosed with placebo in each cohort.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/18/2023
Locations: Viking Clinical Site 207, Gainesville, Florida
Conditions: Adrenomyeloneuropathy Form (AMN) of X-linked Adrenoleukodystrophy (X-ALD)