Florida is currently home to 3831 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)
Recruiting
The purpose of this research is to understand and treat Traumatic Brain Injury (TBI) associated photophobia (light sensitivity) and its impact on visual function.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: University of Miami, Miami, Florida
Conditions: Traumatic Brain Injury
Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression
Recruiting
This single-cohort, prospective case series is designed to evaluate and characterize the use of Axoguard HA+ Nerve Protector™ to protect the ulnar nerve in a first revision cubital tunnel decompression procedure. Data on the primary cubital tunnel syndrome decompression, first revision decompression utilizing Axoguard HA+ Nerve Protector, participant-reported pain, motor and sensory functional outcomes, quality of life (QoL) outcomes, and recurrence/revision will be collected. This case series w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Foundation for Orthopaedic Research and Education (Florida Orthopaedic Institute), Tampa, Florida
Conditions: Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Feasibility of a Smartphone Application for Asthma Self-management
Recruiting
The primary goal of this project is to determine the feasibility, acceptability, and adherence of a smartphone application for improving asthma self-management in a pilot randomized controlled trial (RCT). The app is specifically designed to appeal to adolescents. Adolescents with persistent asthma will be randomized to receive: 1) standard-of-care or 2) the self-management app in addition to standard-of-care. Feasibility will be assessed by the ability to recruit and retain subjects, technical... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/30/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Asthma Chronic
Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases
Recruiting
The purpose of this study is to create a repository for cerebellar ataxia and nucleotide repeat diseases in order to fully investigate the genetic and phenotypic presentations of both.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Spinocerebellar Ataxias, Cerebellar Ataxia, Nucleotide Repeat Disease
The EBC Recovery Study
Recruiting
The purpose of this research study to find out if clinically unconscious acute brain injury patients that show brain activation to music and language on electroencephalogram (EEG) (bedside test) have better outcomes and wake up in the future.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: Jackson Memorial Hospital, Miami, Florida
Conditions: Traumatic Brain Injury, Intracerebral Haemorrhage, Subarachnoid Haemorrhagic Stroke
Evaluation of Tasso+ Blood Self-Collection for Clinical Diagnostic Assessment of Various Biomarkers
Recruiting
This study aims to assess the effectiveness and reliability of the Tasso+ capillary blood self-collection device in the clinical diagnostic assessment of various biomarkers. The study will collect blood specimens using both the Tasso+ self-collection device and traditional venipuncture. The biomarker analysis results from both specimen types will be compared for correlation.
Gender:
ALL
Ages:
13 years and above
Trial Updated:
09/26/2024
Locations: American Research Labs, Atlantis, Florida
Conditions: Blood Self-Collection for Clinical Diagnostic Assessments
Olorofim Aspergillus Infection Study
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Invasive Aspergillosis
Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes
Recruiting
The overall aim of this pilot study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
Gender:
ALL
Ages:
Between 30 years and 65 years
Trial Updated:
09/26/2024
Locations: AdventHealth Translational Research Institute, Orlando, Florida
Conditions: Type 2 Diabetes
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
Recruiting
This study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The primary endpoints are: Dose limiting toxicities (Parts A-1 and A-2), Overall response rate per RECIST v1.1 (Parts B1-B7), Safety and tolerability (Parts B-8, B-9 and C),... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Ocala Oncology Center, Ocala, Florida
Conditions: Advanced Solid Tumor, Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Ovarian Neoplasm, Hormone Receptor Positive, HER2-negative Neoplasms, Hormone Receptor Positive, HER2-low Neoplasms, Breast Neoplasms, Non-Small-Cell Lung Neoplasms
A Study to Check the Safety of Dexlansoprazole and Learn If it Can Heal Erosive Esophagitis (EE) and Keep it Healed in Children 2 to 11 Years Old
Recruiting
Gastroesophageal reflux disease (GERD) is caused by food or acid coming up from the stomach into the esophagus, repeatedly. The esophagus is the tube that carries food and liquids from the mouth to the stomach. The body uses stomach acid to break down food, but when acid rises up into the esophagus it can hurt or damage it. People with GERD often feel food coming back up into the throat and mouth and have a burning feeling in their stomach, chest, or throat, called heartburn. Other symptoms of G... Read More
Gender:
ALL
Ages:
Between 2 years and 11 years
Trial Updated:
09/25/2024
Locations: D&H National Research Centers, Miami, Florida
Conditions: Erosive Esophagitis
A Study of Radspherin® in Patients with Primary Advanced Epithelial Cancer, with Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
Recruiting
This is a Phase 2, controlled, randomised, parallel assignment, open label, multicentre study to evaluate efficacy and safety of a single intraperitoneal injection of Radspherin® in patients with primary advanced high-grade serous or high-grade endometrioid epithelial ovarian cancer, fallopian tube, or primary peritoneal cancer, with peritoneal metastasis that are HR proficient and scheduled to undergo NACT and IDS. The study will be conducted in 2 parts; first, a Safety Lead-in Cohort will be r... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Peritoneal Carcinomatosis, Ovarian Cancer
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 narcolepsy, who were exposed to previously tested doses of TAK-861.
Gender:
ALL
Ages:
Between 16 years and 70 years
Trial Updated:
09/24/2024
Locations: Florida Pediatric Research Institute, Orlando, Florida
Conditions: Narcolepsy Type 1