Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Latent Aging Mechanisms in Pain and Sleep
Recruiting
Chronic pain is a serious public health problem in older adults depending on the pain condition, and the capacity to sleep properly changes with age. Given the potential mechanistic role of GABA (gamma-aminobutyric acid) in both conditions, based on our preliminary data, this proposal will determine the effect of oral GABA administration in sleep quality and pain in older adults with chronic pain and sleep disorders as well as to characterize the potential neurobiological mechanisms involved in... Read More
Gender:
All
Ages:
Between 45 years and 100 years
Trial Updated:
06/12/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Chronic Pain
In-Utero Endoscopic Correction of Spina Bifida
Recruiting
The purpose of this study is to evaluate the feasibility and effectiveness of performing fetoscopic surgical correction of fetal spina bifida. Two surgical approaches will be utilized: the percutaneous technique versus the laparotomy/uterine exteriorization technique.
Gender:
Female
Ages:
Between 18 years and 52 years
Trial Updated:
06/12/2023
Locations: Wellington Regional Medical Center, Wellington, Florida
Conditions: Neural Tube Defects, Spina Bifida, Myelomeningocele
A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery
Recruiting
The main aim is to see if danavorexton can help improve people's breathing in the recovery room after abdominal surgery.
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
06/09/2023
Locations: Mayo Clinic Jacksonville - PPDS, Jacksonville, Florida
Conditions: Sleep Apnea
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia, Rheumatoid Arthritis
IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC
Recruiting
A Phase II Multi-Arm (basket) Trial Investigating the Safety and Efficacy of IO102-IO103 in Combination with pembrolizumab, as First-line Treatment for Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC), Squamous Cell Carcinoma of Head or Neck (SCCHN), or Metastatic Urothelial Bladder Cancer (mUBC)
Gender:
All
Ages:
18 years and above
Trial Updated:
06/09/2023
Locations: Mid Florida Hematology and Oncology Center, Orange City, Florida
Conditions: Lung Cancer Non Small Cell, Head and Neck Squamous Cell Carcinoma, Urothelial Carcinoma Bladder
Obesity and Uric Acid Stones Study
Recruiting
The investigator proposes an 18 month, feasibility pilot study, randomizing obese and diabetic individuals with pure uric acid nephrolithiasis (UAN) or mixed calcium oxalate (CO) UAN to either phentermine/topiramate or a pragmatic control group who will remain on their standard medication regimen (citrate salts, allopurinol, diet, etc.).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Obesity, Uric Acid Stones, Type 2 Diabetes Mellitus in Obese, Pre-Diabetes
Home Operations Utilizing Stimulation
Recruiting
This project will utilize a home-operated stimulator in 1) a healthy young adult population and 2) a healthy older adult population to provide a proof of concept of home-use of transcutaneous vagal nerve stimulation (tVNS). tVNS is believed to modulate cognitive performance.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/09/2023
Locations: University of Florida McKnight Brain Institute, Gainesville, Florida
Conditions: Cognitive Performance
Multi-center Evaluation of the Clinical Utility of ESD in the Western Population
Recruiting
The aim of this multi-center study is to prospectively document the clinical utility of ESD.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Endoscopic Submucosal Dissection
TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
Recruiting
A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/09/2023
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Barrett's Esophagus, Esophageal Cancer
Analysis of CA-MRSA Transmission: An ED Population Sampling Strategy
Recruiting
Given that the Emergency Department (ED) has become the entry way for large populations of patients into the health care system, a strategy of sampling MRSA isolates in ED populations and merging this information with patient-level data may present a window to hypothesize and investigate CA-MRSA transmission within the community and its impact on hospital-acquired infections.
Gender:
All
Ages:
1 month and above
Trial Updated:
06/09/2023
Locations: UF Health, Gainesville, Florida
Conditions: Methicillin-Resistant Staphylococcus Aureus
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
Recruiting
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle performance-based measures combined with patient education about breathing on the toilet will improve patient satisfaction scores in individuals with chronic constipation (CC).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: University of Miami, Coral Gables, Florida
Conditions: Constipation, Constipation - Functional, Dyssynergia
The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Kidney Transplant Rejection