Florida is currently home to 3771 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Recruiting
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in Intraocular Pressure (IOP) in robotic case in steep Trendelenburg with IV anesthetics (TIVA). We want to quantify the degree of change in Intraocular Pressure (IOP) in female patients undergoing robotic procedures for cancer. We want to detect the difference in increase of... Read More
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
05/29/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Intraocular Pressure, Oncology
Gastric Ultrasound for Estimation of the Aspiration Risk Study
Recruiting
The purpose of this research study is to look at the effectiveness of current anesthesia guidelines regarding food and drink prior to surgery in patients who are likely to have food and drink remain in their stomach longer than might ordinarily be expected.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/29/2024
Locations: United States, Florida UF Health, Gainesville, Florida
Conditions: Respiratory Aspiration of Gastric Contents
IS-001 Injection in Patients Undergoing Robotic-Assisted Gynecological Surgery
Recruiting
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation.
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
05/28/2024
Locations: HCA Mercy Hospital, Miami, Florida
Conditions: Ureter Injury
Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)
Recruiting
This mechanistic clinical trial proposes to test whether a five-day course of mindfulness meditation training (MMT) and tDCS, and their combination, can enhance pain modulatory balance and pain-related brain function, reduce clinical pain, among African Americans and non-Hispanic whites with knee osteoarthritis (OA). This approach will provide evidence that targeting stress and pain-related brain function will reduce OA-related pain and ethnic group differences therein.
Gender:
ALL
Ages:
Between 45 years and 85 years
Trial Updated:
05/28/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Osteoarthritis of Knee
Effects of Breathing and Attention Training (BAT) on Pain Modulation
Recruiting
The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will be used to evaluate the effects of Breathing Attention Training (BAT) on the hypersensitivity of FM participants. BAT is a form of mindfulness meditation show... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/24/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: University of Miami Hospital, Miami, Florida
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension
Recruiting
This study aims to evaluate the efficacy and safety of inhaled treprostinil in subjects with sarcoidosis-associated interstitial lung disease and pulmonary hypertension.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/24/2024
Locations: University of Florida, Division of Pulmonary and Critical Care Medicine, Gainesville, Florida
Conditions: Sarcoidosis, Precapillary Pulmonary Hypertension, Interstitial Lung Disease
Dosing of Methadone for Spine Surgery
Recruiting
This study compares two methods of dosing methadone for complex spine cases
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/24/2024
Locations: UF Health, Gainesville, Florida
Conditions: Pain, Postoperative
Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
Recruiting
Approximately a fourth of children with seizures do not respond adequately to available therapy. Ketogenic therapy has a long history as treatment for intractable epilepsy, but there is no agreement concerning how it works and what is the best way to administer it. This natural history study will collect data pertaining to both questions.
Gender:
ALL
Ages:
50 years and below
Trial Updated:
05/24/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Seizures
PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung
Recruiting
PCSK9 mediates immune checkpoint blockade resistance by downregulating tumor cell surface MHC class 1 molecules. This study will evaluate if combining the anti-PCSK9 antibody alirocumab with the anti-PD-1 antibody cemiplimab can generate anti-tumor activity and clinical responses in patients with metastatic lung cancer who have progressed on first line immune checkpoint blockade therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Non-small Cell Lung Cancer (NSCLC)
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: University of Florida Health Shands Hospital, Gainesville, Florida
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
A First in Human Trial Evaluating THB335 in Healthy Participants
Recruiting
This study is a double blind, randomized, placebo-controlled, Phase 1 study in two parts: single ascending doses and food effect (Part 1) and multiple ascending doses (Part 2).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/21/2024
Locations: QPS Miami, Miami, Florida
Conditions: Healthy