Florida is currently home to 3831 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Promising ROd-cone DYstrophy Gene TherapY
Recruiting
This is a two-step, multicenter, Phase I/II study including an open-label dose-escalation phase (Step 1) and a three-arm, controlled, double-masked, randomized extension phase (Step 2), in subjects with advanced RCD due to a mutation in the RHO, PDE6A, or PDE6B gene.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/11/2024
Locations: Bascom Palmer Eye Institute/University of Miami, Miami, Florida
Conditions: Retinitis Pigmentosa
Encore PFO Closure Device - The PerFOrm Trial
Recruiting
The objective of this study is to establish reasonable assurance of safety, effectiveness, and noninferiority of the Encore PFO closure device when compared to any investigator chosen FDA-approved PFO closure device.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
09/11/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Patent Foramen Ovale, Cryptogenic Stroke
Planned Semi-Elective Lung Tx Study
Recruiting
When suitable donor lungs become available for a consented recipient, and the donor cross clamp time occurs between 6pm and 4am, the transplant procedure (anesthesia starting time) will be allowed to be moved to a 6am start or later with the lungs being preserved at 10C cold static preservation upon organ arrival to our hospital using a specific refrigerator. The maximum allowed time between donor cross clamp and recipient anesthesia initiation will be 12h.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
09/11/2024
Locations: UFHealth Shands, Gainesville, Florida
Conditions: To Compare Lung Transplant Outcomes Between Study Patients and Standard Patients Who Have Already Undergone Lung Transplantation by Conventional Procedures, Lung Transplant
FAMILY Sleep Program
Recruiting
The purpose of this study is to learn about sleep behaviors and test different ways to help patients with cancer and partners. Participants (patient-sleep-partner caregivers dyads as a unit) participate in the study together.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Cancer
Suture Repair vs Mesh Repair for Incisional Hernia
Recruiting
The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Incisional Hernia
Artificial Intelligence to Measure Adherence to Oral Medication
Recruiting
The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Citrus Health, Hialeah, Florida
Conditions: First Episode Psychosis
Disengagement in CSC: Identifying Those at Risk and Addressing Their Needs
Recruiting
Maintaining treatment engagement is critical for first episode psychosis patients to experience gains possible with coordinated specialty care (CSC). This study is designed to identify CSC participants still receiving care but at high risk for disengagement and to intervene to prevent/delay disengagement.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Henderson Behavioral Health, Lauderdale Lakes, Florida
Conditions: First Episode Psychosis
Early-Phase Schizophrenia: Practice-based Research to Improve Outcomes
Recruiting
The goal if the project is to develop a learning health network devoted to the treatment of first episode psychosis.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Henderson Behavioral Health, Lauderdale Lakes, Florida
Conditions: First Episode Psychosis
Biomarkers in Friedreich's Ataxia
Recruiting
The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.
Gender:
ALL
Ages:
Between 8 years and 70 years
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Friedreich's Ataxia
Dysarthria Management for Minor Groups
Recruiting
This study develops and conduct a small-scale clinical trial study in which the linguistic and cultural diversity of the participants is considered. Speech therapy and counseling services are provided to both patients with Parkinson\'s disease and their caregivers.
Gender:
ALL
Ages:
Between 25 years and 85 years
Trial Updated:
09/09/2024
Locations: Florida State University, Tallahassee, Florida
Conditions: Parkinson Disease, Dysarthria
Pilot Trial of the RUBI Program for Autistic Adults
Recruiting
The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors. The main questions it aims to answer are: * Is the redesigned RUBI intervention feasible and acceptable for autistic adults and their families? * Does the redesigned RUBI intervention reduce challenging behaviors and enhance the quality of life for autistic adults? * Rese... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: Els for Autism Foundation, Jupiter, Florida
Conditions: Autism Spectrum Disorder, Behavior, Parenting
Pharmacokinetics and Safety of Epidiferphane and Taxanes in Breast Cancer Patients
Recruiting
Patients with breast cancer are commonly treated with taxane chemotherapy. Some very common side effects of taxanes, such as anemia and peripheral neuropathy, are often as not well addressed during treatment, resulting in dose reductions, dose delays and early discontinuation (collectively called relative dose intensity) of these chemotherapy agents in 15-80 % of patients on these drugs. This reduction in relative dose intensity (RDI) results in worse clinical outcomes such as progression free a... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
09/09/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Breast Cancer