Florida is currently home to 3828 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
Recruiting
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance, MRD is assessed to guide further therapy. MRD-positive patients will continue with the assigned treatment. MRD-negative patients will be further randomized (Reg Ste... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/21/2024
Locations: AdventHealth Altamonte, Altamonte Springs, Florida
Conditions: Multiple Myeloma
Pediatric Precision Laboratory Advanced Neuroblastoma Therapy
Recruiting
A prospective open label, multicenter study to evaluate the feasibility and acute toxicity of using molecularly guided therapy in combination with standard therapy followed by a Randomized Controlled Trial of standard immunotherapy with or without DFMO followed by DFMO maintenance for Subjects with Newly Diagnosed High-Risk Neuroblastoma.
Gender:
ALL
Ages:
22 years and below
Trial Updated:
08/21/2024
Locations: Nicklaus Children's Miami, Miami, Florida
Conditions: Neuroblastoma
Male Fertility Program
Recruiting
Following spinal cord injury, most men are infertile and require medical assistance to father children. The conditions that contribute to their infertility are erectile dysfunction, ejaculatory dysfunction, and semen abnormalities. The Miami Project Male Fertility Program is a research study designed to understand and improve impairments to male fertility resulting from spinal cord injury.
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
08/21/2024
Locations: The Maimi Project to Cure Paralysis, Miami, Florida
Conditions: Spinal Cord Injury
Evaluative Conditioning and Relationship Satisfaction
Recruiting
The overall objective is to evaluate the efficacy of a novel computerized learning procedure to enhance marital well-being among military members and their partners.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Florida State University, Tallahassee, Florida
Conditions: Relationship, Marital
NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
Recruiting
This study is a double-blind, randomized controlled trial comparing the effectiveness of oral acetaminophen, diclofenac, and tramadol in reducing the consumption of narcotic doses (primary outcome) and minimizing patients' exposure to narcotics (secondary outcome) following an ultrasound-guided percutaneous needle tenotomy procedure on the lateral elbow.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/20/2024
Locations: The Cleveland Clinic Florida, Coral Springs, Florida
Conditions: Elbow Pain, Chronic Pain
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: South Lake Pain Institute, Clermont, Florida
Conditions: Painful Diabetic Neuropathy
CHOICES3: Sickle Cell Disease Parenting CHOICES
Recruiting
The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/20/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Sickle Cell Disease, Sickle Cell Trait
Trial to Assess Chelation Therapy in Critical Limb Ischemia
Recruiting
TACT3a is a double blind, placebo-controlled, randomized trial to test a novel therapy, edetate disodium-based chelation of environmentally acquired toxic metals, to reduce cardiovascular events including amputation in high-risk diabetic patients.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/20/2024
Locations: Mount Sinai Medical Center, Miami Beach, Florida
Conditions: Critical Limb Ischemia, Diabetes
Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia
Recruiting
Hypoxic-Ischemic Encephalopathy (HIE) occurs in 20 per 1000 births. Only 47% of neonates treated with the state of the art therapy (induced systemic hypothermia) have normal outcomes. Therefore, other promising therapies that potentially work in synergy with hypothermia to improve neurologic outcomes need to be tested. One potential agent is melatonin. Melatonin is a naturally occurring substance produced mainly from the pineal gland. Melatonin is widely known for its role in regulating the circ... Read More
Gender:
ALL
Ages:
6 hours and below
Trial Updated:
08/20/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Hypoxic Ischemic Encephalopathy
Geolocation Positional System (GPS) Experience
Recruiting
The purpose of this study is to use smartphone technology to capture individual location emotional and cognitive data, to examine how real-world behaviors thoughts, emotions, and brain activity are related to one another.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
08/19/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Emotions, Anhedonia, Depression
Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes
Recruiting
The brief purpose of this research study is to learn about the safety and efficacy of intra-arterial administration of CELZ-201 in patients with newly diagnosed Type 1 Diabetes Mellitus (T1D).
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
08/19/2024
Locations: Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, Florida
Conditions: Type 1 Diabetes, Diabetes Mellitus, Type 1
Rh-PDGF vs EMD for Treatment of Intra-bony Defects
Recruiting
Treatment of intra-bony defects is challenging and requires extensive knowledge of the etiology, anatomy, occlusion, and available biomaterials that can be used to treat this kind of defects. Patients who received scaling and root planing at the college of dental medicine due to periodontal disease, will be screened for inclusion. Only subjects who showed persistent deep probing depth associated with an intrabony defect will be included and will be randomly allocated to one of two treatment grou... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Nova Southeastern University, Davie, Florida
Conditions: Intrabony Periodontal Defect