Florida is currently home to 3848 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia
Recruiting
The purpose of this study is to assess whether APG-157 can reduce the tumor size in participants with the study disease. Another purpose is to find out about the effects of APG-157 on certain tumor markers and oral rinses in participants with the study disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2023
Locations: University of Miami, Miami, Florida
Conditions: Oropharyngeal Dysplasia, Oral Cavity Dysplasia, Oral Carcinoma in Situ
Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)
Recruiting
The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics) post-TAVR.
Gender:
All
Ages:
All
Trial Updated:
06/06/2023
Locations: Tenet Health, Boca Raton, Florida
Conditions: Aortic Stenosis, Aortic Valve Stenosis
Iron Supplementation and Intestinal Health
Recruiting
This is a randomized double-blinded study of enteral iron supplementation in Very Low Birth Weight infants. The subjects will be randomized into low dose (2 mg/kg/day) and high dose (6 mg/kg/day) of daily iron supplementation. The primary outcomes are intestinal health including microbiome, inflammation, and barrier function.
Gender:
All
Ages:
Between 1 day and 6 months
Trial Updated:
06/06/2023
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Anemia of Prematurity, Very Low Birth Weight Infant
SurvivorLink: Scalability of an Electronic Personal Health Record
Recruiting
Previous research suggests that children and adolescents with cancer are at heightened risk of late effects that can occur months or years after cancer treatment, yet little is known about programs that increase their return for follow-up cancer care and late effects surveillance. This study will evaluate the impact of an electronic personal health record and education system, SurvivorLink, for pediatric cancer survivors and their caregivers. The researchers will develop a standardized intervent... Read More
Gender:
All
Ages:
All
Trial Updated:
06/06/2023
Locations: Arnold Palmer Hospital for Children, Orlando, Florida
Conditions: Childhood Cancer
Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications
Recruiting
The purpose of this study is to develop and refine the techniques for using magnetic resonance imaging and magnetic resonance spectroscopy to understand the composition and function of the human body
Gender:
All
Ages:
Between 12 years and 89 years
Trial Updated:
06/06/2023
Locations: Translational Research Institute for Metabolism and Diabetes, Orlando, Florida
Conditions: Human Body Composition, Human Body Function
Magnetic Resonance & Optical Spectroscopy Validation
Recruiting
The purpose of this study is to develop and refine techniques for using magnetic resonance and optical spectroscopy to investigate how your body uses energy.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
06/06/2023
Locations: Translational Research Institute for Metabolism and Diabetes, Orlando, Florida
Conditions: Validation Studies, Magnetic Resonance Spectroscopy
Exercise to Boost Response to Checkpoint Blockade Immunotherapy
Recruiting
30 minutes of moderate exercise on an arm ergometer, a cycle ergometer, or a treadmill prior to each administration of standard of care checkpoint blockade immunotherapy across all cycles
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Cutaneous Melanoma, Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma
The Less is More Study
Recruiting
In this project, the investigators will implement innovations to extend use of Contingency Management (CM) to facilitate alcohol use reduction among people living with HIV (PLWH). The investigators' approach to extending CM will use mobile health (mHealth) tools including a smartphone breathalyzer device with accompanying app and a wrist worn alcohol biosensor. Participants will be engaged in mobile facilitated CM for 30-60 days with follow-up out to 6 months.
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
06/05/2023
Locations: University of Miami, Coral Gables, Florida
Conditions: Alcohol Use
Real World Evidence With the Debritom+ TM Novel Micro Water Jet Technology at a Single Wound Center
Recruiting
Prospective, single-blinded, single-center, parallel group, randomized controlled trial (RCT) to assess rate and frequency of wound healing and associated financial savings, when using Medaxis debritom+ versus standard of care as a choice of debridement method, where both arms follow normal wound care practice in use of advanced wound care treatments.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: MCR Health, Inc., Bradenton, Florida
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Surgical Wound Dehiscence, Traumatic Wounds
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
Recruiting
The purpose of this clinical investigation is to assess performance of the Medaxis Debritom+™ and to collect subject outcome data in the treatment of diabetic foot ulcers (DFU) vs Standard sharp debridement.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: Doctors Research Network, South Miami, Florida
Conditions: Diabetic Foot Ulcer, Diabetic Foot
Tailoring P2Y12 Inhibiting Therapy in Patients Requiring Oral Anticoagulation After PCI
Recruiting
Clopidogrel is the P2Y12 inhibitor of choice in PCI patients requiring OAC. However, concerns have been raised based on the notion that a considerable number of patients may have inadequate response to clopidogrel. Although practice recommendations indicate that the use of potent P2Y12 inhibitors (i.e., ticagrelor) may be considered in patients at increased thrombotic risk, they do not recommend routine testing to identify patients with poor response to clopidogrel. The aim of this study is to a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: University of Florida, Jacksonville, Florida
Conditions: Coronary Artery Disease
Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)
Recruiting
The goal of the study is to examine the ability of resistance or aerobic exercise training to "imprint" skeletal muscle cells in a manner which confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through epigenetic regulation of novel exercise response genes. This study will also provide primary human skeletal muscle cells to the Molecular Transducers of Physical Activity Consortium (MoTrPAC) (NCT03960827) repository for future u... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: AdventHealth Translational Research Institute, Orlando, Florida
Conditions: Physical Activity