Florida is currently home to 3811 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels
NCT05480761
Recruiting
This is a Phase 4, U.S. only, multi-center study using a 7-day therapeutic response dose (TRD) of commercial Sucraid® to assess the response of treatment in 1100 symptomatic pediatric (6 months to 17 years old) subjects with low, moderate, and normal sucrase activity determined by a disaccharidase assay via EGD within 1 year of the Screening Visit. This study will also explore the relationship between known genetic CSID mutations and sucrase activities via (EGD) disaccharidase assay (low, modera... Read More
Gender:
All
Ages:
Between 6 months and 17 years
Trial Updated:
11/14/2023
Locations: Kidz Medical, Coral Gables, Florida
Conditions: Congenital Sucrase-Isomaltase Deficiency, CSID, Sucrase Isomaltase Deficiency
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The KinematX Midcarpal Total Wrist Arthroplasty Registry
NCT05719935
Recruiting
The goal of this observational study is to learn about functional and patient reported outcomes in patient undergoing total wrist replacement with the KinematX total wrist replacement study. The main questions it aims to answer are: What is the range of motion (flexion, extension, radial, ulnar, grip and pinch strength) at 3-, 6-, and 12-months after surgery and yearly up to 10 years among patients having total wrist replacement with the KinematX implant. What are the patient reported outcomes... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/13/2023
Locations: Florida Orthopaedic Institute, Tampa, Florida
Conditions: Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS), Kienbock's Disease of Adults, Radial Malunion, Ulnar Translocation, Post Traumatic Arthritis, Inflammatory Arthritis, Osteoarthritis, Scaphoid Non-union Advanced Collapse (SNAC)
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Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants
NCT05547165
Recruiting
Patent Ductus Arteriosus is a developmental condition commonly observed among preterm infants. It is a condition where the opening between the two major blood vessels leading from the heart fail to close after birth. In the womb, the opening (ductus arteriosus) is the normal part of the circulatory system of the baby, but is expected to close at full term birth. If the opening is tiny, the condition can be self-limiting. If not, medications/surgery are options for treatment. There are two ways... Read More
Gender:
All
Ages:
Between 7 days and 32 days
Trial Updated:
11/12/2023
Locations: Joe DiMaggio Children's Hospital, Hollywood, Florida
Conditions: Ductus Arteriosus, Patent
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The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
NCT05811364
Recruiting
The objective of this prospective, multicenter, randomized, controlled clinical trial is to demonstrate the superiority of the VBX Device for primary patency when compared to bare metal stenting in complex iliac occlusive disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/07/2023
Locations: Radiology and Imaging Specialists of Lakeland, Lakeland, Florida
Conditions: Aortoiliac Occlusive Disease, Peripheral Arterial Disease
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Breathing & Blood Pressure
NCT05632406
Recruiting
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.
Gender:
All
Ages:
Between 20 years and 45 years
Trial Updated:
11/07/2023
Locations: Florida State University, Tallahassee, Florida
Conditions: Healthy, Overweight and Obesity
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Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients
NCT06054529
Recruiting
To learn how altered metabolism in GBM causes tumor growth and resistance to drug therapy. In this pilot research study, we will dose GBM patients with a form of nicotinamide (a natural vitamin) that we can track. The nicotinamide will be converted to methyl nicotinamide (MeNAM) in the tumor. We will measure how fast the nicotinamide is converted to methyl nicotinamide. We believe that the speed of this chemical reaction in the tumor (fast versus slow) may be correlated with GBM aggressiveness
Gender:
All
Ages:
18 years and above
Trial Updated:
11/06/2023
Locations: AdventHealth Translational Research Institute, Orlando, Florida
Conditions: Glioblastoma Multiforme
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Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD
NCT06064071
Recruiting
Clinical Study Evaluating Nordlys™ System with Selective Waveband Technology (SWT)® Intense Pulsed Light (IPL) Applicators for Dry Eye Disease (DED) due to Meibomian Gland Dysfunction (MGD).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/02/2023
Locations: Center for Excellence in Eye Care, Miami, Florida
Conditions: Meibomian Gland Dysfunction, Dry Eye Disease
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A Pharmacist-run PrEP Program for Women
NCT05755204
Recruiting
The primary objective of this study is to evaluate uptake and retention of long acting cabotegravir (LA-CAB) also known as Apretude versus daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) also known as Truvada for PrEP among high-risk women in metro-Orlando through week 48 (to also include reasons for lack of retention in PrEP care)
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
11/02/2023
Locations: Orlando Immunology Center, Orlando, Florida
Conditions: HIV Prevention
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Changes in Immunologic Parameters Following the Addition of Fostemsavir in Virologically Suppressed Immunologic Non-responders Living With HIV-the RECOVER Study
NCT05220358
Recruiting
The RECOVER study is a self-controlled case series to evaluate whether the addition of Fostemsavir (Rukobia) to a stable HIV regimen in virologically suppressed patients living with HIV who never experience optimal CD4 T-cell count recovery can result in meaningful increases in different immunologic parameters such as CD4 T-cell count, CD4 T-cell percentage and CD4/CD8 ratio
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/02/2023
Locations: Orlando Immunology Center, Orlando, Florida
Conditions: HIV-1-infection
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Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG
NCT05630209
Recruiting
The purpose of this study is to evaluate the safety and efficacy of targeted blood brain barrier disruption with Exablate Model 4000 Type2.0/2.1 in combination with Doxorubicin therapy for the treatment of DIPG in pediatric patients
Gender:
All
Ages:
Between 5 years and 21 years
Trial Updated:
11/01/2023
Locations: Nicklaus Children's Hospital, Miami, Florida
Conditions: Brain Tumor
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A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects
NCT03028246
Recruiting
The goal of this prospective, non-randomized, single-arm, feasibility study is to develop data to evaluate the safety and feasibility of ExAblate 4000 treatment of benign intracranial tumors which require clinical intervention in pediatric and young adult subjects. Indication of Use: Ablation of benign intracranial tumors in children and young adults which are ExAblate accessible.
Gender:
All
Ages:
Between 8 years and 22 years
Trial Updated:
11/01/2023
Locations: Nicklaus Children's Hospital Insititute, Miami, Florida
Conditions: Benign Centrally-Located Intracranial Tumors
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A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
NCT06112340
Recruiting
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled in the prior VGN-TED-301 through Week 24. These subjects include VGN-TED-301 Week 24 proptosis non-responders or subjects who relapse during the Follow-Up Period of VGN-TED-301.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: Bascom Palmer Eye Institute, Miami, Florida
Conditions: Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases, Thyroid Associated Ophthalmopathy, Graves Ophthalmopathy, Thyroid Diseases, Orbital Diseases, Proptosis, IGF1R, Exophthalmos, Hashimoto
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