Florida is currently home to 3804 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)
Recruiting
The goal of this clinical trial is to test the safety and efficacy of KVA12123 alone or combined with pembrolizumab in patients with advanced solid tumors. The main questions this study aims to answer are: What is the safety of KVA12123 when administered alone and in combination with pembrolizumab to advanced cancer patients? What is an appropriate dose of KVA12123 to administer alone and in combination with pembrolizumab to advanced cancer patients in future clinical trials? Participants in t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: Sarah Cannon Research Institute at Florida Cancer Specialists, Sarasota, Florida
Conditions: Cancer, Solid Tumor, Melanoma, Carcinoma, Sarcoma, Lung Cancer, Prostate Cancer, Breast Cancer, Colo-rectal Cancer, Uterine Cancer, Pancreatic Cancer, Gastric Cancer, Esophageal Cancer, Thyroid Cancer, Ovarian Cancer, Kidney Cancer, Head and Neck Cancer
Clinical Course of Alcohol Use Disorder Recovery
Recruiting
The goal of this single-arm clinical trial is to better understand the ways in which individuals seeking treatment recover from Alcohol Use Disorder (AUD). The main aims are to: To establish operational definitions of types of change in relation to National Institute on Alcohol Abuse and Alcoholism's (NIAAA) new definition of recovery, and to distinguish between treatment response, remission versus recovery, and relapse versus recurrence. To describe patterns of recovery, including the frequenc... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: University of South Florida, Tampa, Florida
Conditions: Alcohol Use Disorder
ALG.APV-527 First-in-human Study
Recruiting
A first-in-human, multicenter, open-label, dose escalation and dose expansion phase 1 study in patients with advanced solid tumors to evaluate the safety of intravenously administered ALG.APV-527 (Short title: ALG.APV-527 first-in-human study). Adult patients with advanced/metastatic solid tumors likely to express 5T4 antigen who have failed standard of care regimens for their cancer, have become refractory to standard treatment, or for whom no effective therapy exists based on investigator judg... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/28/2023
Locations: Hematology Oncology Associates Of The Treasure Coast, Port Saint Lucie, Florida
Conditions: Solid Tumor
Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care
Recruiting
Phase IV, randomized, prospective, multi-center, open-label, comparison of transforming powder dressing to standard of care dressing for healing diabetic foot ulcers.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
06/27/2023
Locations: AdventHealth Medical Group Foot & Ankle at Winter Park, Winter Park, Florida
Conditions: Diabetic Foot Ulcer
Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection
Recruiting
The study will compare EMR versus ESD technique (both combined with subsequent ablative therapy) of mucosal resection in Barrett's esophagus with regard to efficacy and risk in a long term setting.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/27/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Barrett Esophagus, Barrett Adenocarcinoma, Esophagus Neoplasm
Electromagnetic Fields Versus Placebo For Child-Pugh A and B Patients With Advanced Hepatocellular Carcinoma
Recruiting
The primary goals of this study are to compare overall survival and quality of life in subjects with Child-Pugh A or B advanced hepatocellular carcinoma when treated with a device emitting radiofrequencies modulated at specific frequencies or with a device emitting unmodulated radiofrequencies.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/25/2023
Locations: Tampa General Hospital, Tampa General Cancer Center, Tampa, Florida
Conditions: Hepatocellular Carcinoma
A Diagnostic Study of CD38-Targeted ImmunoPET of Myeloma
Recruiting
Evaluation of myeloma disease burden is currently suboptimal. This limits treatment planning and evaluation of residual disease following treatment. 89Zr-DFO-daratumumab is a novel immunoPET tracer, designed to detect CD38 on myeloma cells and allow visualization of myeloma in a PET scanner. A phase I study of 89Zr-DFO-daratumumab demonstrated safety and successful visualization of myeloma with 89Zr-DFO-daratumumab. This will be a phase II study of 89Zr-DFO-daratumumab to evaluate potential clin... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
06/23/2023
Locations: University of Miami, Miami, Florida
Conditions: Multiple Myeloma
Photobiomodulation for Myofascial Pelvic Pain
Recruiting
The goal of this clinical trial is to evaluate the efficacy of photobiomodulation of the pelvic floor muscles in female Veterans with chronic pelvic pain. The main questions it aims to answer are: Is there a difference in reduction in overall pelvic pain between women who undergo photobiomodulation compared to women who received pelvic floor physical therapy? Is there a difference in compliance with therapy between the two groups? Participants will be randomized to treatment with either 9 treat... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/21/2023
Locations: Orlando VA Medical Center, Orlando, Florida
Conditions: Pelvic Pain, Levator Ani Syndrome, Spastic Pelvic Floor Syndrome, Chronic Pelvic Pain Syndrome, Myalgia of Pelvic Floor
Central Executive Training and Parent Training for ADHD
Recruiting
The goal of the current project is to combine two evidence- based treatments for school-aged children with ADHD: Central Executive Training (CET) and Behavioral Parent Training (BPT). CET is a computerized training intervention that improves ADHD symptoms and academic functioning by improving children's working memory abilities. BPT is a therapeutic intervention that improves family functioning and child oppositional-defiant (ODD) symptoms by changing parenting behaviors. Their combined use is e... Read More
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
06/20/2023
Locations: Florida State University, Tallahassee, Florida
Conditions: ADHD
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
Recruiting
The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12 months (13 medication cycles) of investigation in comparison to non-hormonal contraceptive methods. Secondary objectives include further evaluating the impact of LF111 and DRSP 3.5 mg chewable tablets on BMD and bone turnover after 12 months (13 medication cycles) in comparison to non-hormonal contraceptive methods and a... Read More
Gender:
Female
Ages:
Between 14 years and 45 years
Trial Updated:
06/15/2023
Locations: Advanced Clinical Research Network, Coral Gables, Florida
Conditions: Change in Bone Mineral Density, Bone Loss
In-Utero Endoscopic Correction of Spina Bifida
Recruiting
The purpose of this study is to evaluate the feasibility and effectiveness of performing fetoscopic surgical correction of fetal spina bifida. Two surgical approaches will be utilized: the percutaneous technique versus the laparotomy/uterine exteriorization technique.
Gender:
Female
Ages:
Between 18 years and 52 years
Trial Updated:
06/12/2023
Locations: Wellington Regional Medical Center, Wellington, Florida
Conditions: Neural Tube Defects, Spina Bifida, Myelomeningocele
TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
Recruiting
A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/09/2023
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Barrett's Esophagus, Esophageal Cancer