Florida is currently home to 3730 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
Recruiting
Stage A: To evaluate the safety and efficacy of red blood cells (RBCs) prepared with the INTERCEPT Blood System for Red Blood Cells Pathogen Reduction Treatment (PRT) in comparison to conventional RBCs in patients who require RBC transfusion support. Stage B: To provide early access to the INTERCEPT pathogen reduction system for RBC in regions where a substantial proportion of the population has been infected or is at risk of a transfusion-transmissible infection. The objectives and design of... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
09/11/2023
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Anemia
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
Recruiting
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo. The secondary objective of this study is to compare the safety of Bonjesta in pregnant adolescents aged 12 to 17 years with placebo.
Gender:
FEMALE
Ages:
Between 12 years and 17 years
Trial Updated:
09/08/2023
Locations: Vital Pharma Research, Hialeah, Florida
Conditions: Morning Sickness
PrEPared-RN, CAN Nurse-Led Management of High-risk Patients for Pre-Exposure Prophylaxis (PrEP)
Recruiting
During the initial encounter, the nurses will complete program enrollment forms (consents and disclosures as approved by IRB), medical history, and risk assessment. If needed, the RN will facilitate a 4th generation rapid HIV test or draw HIV serology. A general review of systems, focused physical exam with emphasis on sexually transmitted infections and signs of seroconversion is provided, including identifying signs of genitourinary infection. The nurse will order labs per standing order and... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/07/2023
Locations: CAN Community Health, Fort Lauderdale, Florida
Conditions: Hiv Prevention, Pre-Exposure Prophylaxis (PrEP)
JAB-21822 Activity in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation
Recruiting
This study is to evaluate the safety and tolerability of JAB-21822 monotherapy and combination therapy in adult participants with advanced solid tumors harboring KRAS G12C mutation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: Mayo Clinc, Jacksonville, Florida
Conditions: Advanced Solid Tumor, NSCLC, CRC
Prospective Observational Exploratory Clinical Study to Determine the Assay Cut-Off for the RadTox Test in Prostate Cancer Patients to Predict Gastrointestinal Radiation Toxicity Using Circulating Cell Free DNA Directly From Plasma
Recruiting
This clinical study is conducted to develop a new test to identify prostate cancer patients at highest risk of radiotherapy-related complications, especially related to gastrolintestinal (GI) toxicities. This clinical study would allow monitoring of total tissue damage in blood samples as early as after the 2nd but before the 4th radiotherapy dose during week 1 of radiotherapy, which could help clinicians make treatment decisions. Detection of excessive tissue damage at this early time, well bef... Read More
Gender:
MALE
Ages:
Between 30 years and 85 years
Trial Updated:
09/06/2023
Locations: University of Florida, Gainesville, FL, Gainesville, Florida
Conditions: Prostate Cancer
Adaptive Response to Intervention (RTI) for Students With ADHD
Recruiting
Purpose: The primary purpose of the proposed project is to investigate the efficacy of Tier 1 and Tier 2 interventions delivered through a Response to Intervention (RTI) framework for children with attention-deficit/hyperactivity disorder (ADHD). Further, for children who do not respond to initial Tier 2 strategies, the proposed study will assess which additional course of intervention is most effective: (1) enhanced Tier 2 strategies or (2) stimulant medication. The majority of youth with ADHD... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/06/2023
Locations: Florida International University Center for Children and Families, Miami, Florida
Conditions: Attention Deficit Disorder With Hyperactivity
Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis
Recruiting
This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/05/2023
Locations: South Lake Pain Institute, Clermont, Florida
Conditions: Osteomyelitis, Diabetic Foot Osteomyelitis
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: IHS Health, Kissimmee, Florida
Conditions: Ulcerative Colitis
AltaValve Early Feasibility Study Protocol
Recruiting
Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/31/2023
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
Recruiting
This study will develop an algorithm of identifying patients with stage IV NSCLC and Melanoma who could benefit from cancer treatment they receive.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/25/2023
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Stage IV Non-small Cell Lung Cancer, Stage IV Small Cell Lung Cancer, Stage III Malignant Melanoma, Stage IV Malignant Melanoma
Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients
Recruiting
The aim of this 6-month randomized multi-regional double-blind parallel group placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/24/2023
Locations: Clinical Research of West Florida, Inc., Clearwater, Florida
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
Recruiting
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension (GRASSP) strength score following a one-month physical therapy run-in period.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/21/2023
Locations: The Miami Project to Cure Paralysis, Miami, Florida
Conditions: Incomplete Spinal Cord Injury