Florida is currently home to 3830 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
New Onset Diabetes Management for Earlier Detection of Pancreatic Cancer (NODMED)
Recruiting
Bluestar Genomics has developed a non-invasive test that aids in detection of occult pancreatic cancer in patients with new onset type II diabetes (NOD) who are 50 years old or older. The purpose of this study is to evaluate the performance of Bluestar Genomics early-detection pancreatic cancer test in a clinical setting. The study is prospective, longitudinal and interventional; tests will be ordered and results returned to site-investigators. If the test returns a pancreatic cancer signal "det... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
12/06/2022
Locations: JEM Research Institute - Headlands - PPDS, Atlantis, Florida
Conditions: Pancreatic Cancer
A Noninterventional, Single-Center Feasibility Study to Evaluate Measures of Heart Failure Risk
Recruiting
This is a non-invasive/observational study in healthy and mild HF subjects utilizing clinical and ambulatory measurements to improve detection, monitoring, and management of HF risks.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/02/2022
Locations: Research Center, Jacksonville, Florida
Conditions: Heart Failure, Cardiomyopathy, Hypertrophic, Left Ventricular Hypertrophy
Knee Related Subchondral Bone Lesions Treated With IOBP
Recruiting
The study will be a prospective, multicenter clinical study evaluating clinical and patient reported outcome measures of subjects receiving IOBP® surgical technique using Angel cPRP and BMA processing system to treat subchondral bone pathology (SBP).
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
12/02/2022
Locations: Andrews Research and Education Foundation, Gulf Breeze, Florida
Conditions: Subchondral Cyst
LungLB in Subjects Presenting With Indeterminate Pulmonary Nodules
Recruiting
Correlate performance of LungLB Test with outcome of a scheduled biopsy.
Gender:
All
Ages:
40 years and above
Trial Updated:
11/29/2022
Locations: Clinical Site 05, Bay Pines, Florida
Conditions: Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies
Recruiting
A Phase I-II, First-in-Human Study of SKB264 in Patients with Locally Advanced Unresectable/Metastatic Solid Tumors who are refractory to Available Standard Therapies. Patient must have historically documented, incurable, locally advanced or metastatic cancer that are refractory to standard therapies of one of the following types: Triple negative breast cancer Epithelial ovarian cancer Non-small cell lung cancer Gastric adenocarcinoma/Gastroesophageal junction adenocarcinoma Small cell lung can... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/29/2022
Locations: Florida Cancer Specialists and Research Institute, Sarasota, Florida
Conditions: Gastric Adenocarcinoma, Breast Cancer, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small-Cell Lung Cancer, Epithelial Ovarian Cancer, Gastroesophageal Junction Adenocarcinoma, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma
A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer
Recruiting
Subjects will be offered the opportunity to participate in a randomized, controlled, 2-arm, unblinded multicenter trial (RCT). There will be 2 study arms: the control arm receiving chemotherapy with the modified FOLFIRINOX regimen alone; and the irreversible electroporation (IRE) arm, receiving chemotherapy with the modified FOLFIRINOX regimen followed by IRE with the NanoKnife System using either an open or a percutaneous approach. All subjects will be treated with the modified FOLFIRINOX regim... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/23/2022
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Stage III Pancreatic Cancer
AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)
Recruiting
The study is designed to evaluate the safety and efficacy of the AngioSafe Peripheral CTO Crossing System.
Gender:
All
Ages:
22 years and above
Trial Updated:
11/22/2022
Locations: Palm Vascular Centers, Miami Beach, Florida
Conditions: Peripheral Artery Occlusion, Peripheral Arterial Disease
Thumb Osteoarthritis Mechanisms
Recruiting
This study examines carpometacarpal osteoarthritis (CMC OA) and aims to elucidate the biomechanical, neuromuscular, and somatosensory mechanisms that contribute to CMC OA symptoms by using orthopaedic biomechanics and quantitative pain testing. Completion of this study will provide a comprehensive dataset describing how movement strategies (muscle activity and joint posture) as well as experimental and clinical pain differ between individuals with CMC OA and age-matched controls.
Gender:
Female
Ages:
Between 40 years and 90 years
Trial Updated:
11/21/2022
Locations: UF Health of University of Florida, Gainesville, Florida
Conditions: Carpometacarpal Osteoarthritis
Preventing Alzheimer's With Cognitive Training
Recruiting
Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residentia... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/21/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer
Recruiting
This is a phase 1/2a, first-in-human study to evaluate the safety and tolerability of LAVA-1207 in patients with therapy refractory metastatic castration resistant prostate cancer
Gender:
Male
Ages:
18 years and above
Trial Updated:
11/18/2022
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Metastatic Castration Resistant Prostate Cancer
Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis
Recruiting
The investigators will investigate the efficacy of dupilumab in patients with severe eosinophilic CRSsNP who are resistant to the conventional treatment with intranasal corticosteroids and have significantly extensive disease involving more than 2 sinuses bilaterally in sinus CT scan and Lund-Mackay sinus (LMK) CT score >=10 at baseline.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2022
Locations: University of South Florida Asthma, Allergy and Immunology, Tampa, Florida
Conditions: Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis
Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
Recruiting
The addition of intranasal oxymetazoline for two weeks to already instituted optimal doses of intranasal fluticasone propionate will decrease the total number of obstructive apneas and hypopneas per hour of sleep in subjects with perennial allergic or non-allergic rhinitis and mild obstructive sleep apnea who have persistent nasal congestion despite maximum doses of NGCS.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/14/2022
Locations: Usf Asthma Allergy and Immunology Cru, Tampa, Florida
Conditions: Sleep Apnea, Chronic Nasal Congestion