Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
Recruiting
The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: COVID-19
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: GSK Investigational Site, Jacksonville, Florida
Conditions: Neoplasms
Reducing Wound Infections Using Bioelectric Wound Dressings
Recruiting
The purpose of this study is to compare the outcomes of using Bioelectric wound dressing on the pre-operative wound site and post operatively and compared it outcomes to the standard of care chlorhexidine skin preparation.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
03/13/2024
Locations: AdventHealth Celebration, Kissimmee, Florida
Conditions: Surgical Site Infection
Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment
Recruiting
PrevisEA is a noninvasive, disposable device that uses audio spectral analysis of sounds produced by the gastrointestinal tract to predict gastrointestinal impairment (GII). GII is most commonly associated with postoperative ileus (POI), but could be the result of other causes, such as early postoperative bowel obstruction. GII is defined as failure of successful early oral re-feeding in a subject undergoing major abdominal surgery. For subjects who are allowed to resume a diet during the first... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
03/11/2024
Locations: Adventist Health System/Sunbelt, Inc. d/b/a AdventHealth Orlando, Orlando, Florida
Conditions: Gastrointestinal Complication
LOWER: Lomitapide Observational Worldwide Evaluation Registry
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: Preventative Cardiology, Inc., Boca Raton, Florida
Conditions: Homozygous Familial Hypercholesterolemia
Prospective SPINE Registry
Recruiting
This study is a prospective, multi-center, open label registry designed to collect real-world data on performance and safety data on RTI's spine products.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Florida Back Institute, Boca Raton, Florida
Conditions: Sacroiliac; Fusion, Sacroiliac, Joint Diseases, Musculoskeletal Diseases, Spinal Disease, Spinal Stenosis, Spinal Instability, Fusion of Joint, Fusion of Spine, Spinal Fusion, Spine
Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.
Recruiting
The goal of this interventional study is to learn about the outcomes between two options for the management of malignant gastric outlet obstruction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: AdventHealth Orlando, Orlando, Florida
Conditions: Malignant Gastric Outlet Obstruction
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
Recruiting
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs. standard telemental health (TMH) to adults with intense fear of dogs, snakes, and/or spiders. The secondary purpose is to preliminarily examine the efficacy of using Doxy.me VR vs. TMH in reducing phobia severity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Arachnophobia, Cynophobia, Ophidiophobia
Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: University of Miami, Miami, Florida
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Recruiting
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Boca Raton, FL Investigative Site, Boca Raton, Florida
Conditions: Heart Failure, Acute Heart Failure
Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas
Recruiting
This is a two-staged, Phase 2/3, randomized, multi-center study to investigate the efficacy and safety of REC-2282 in patients with progressive NF2 mutated meningiomas.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
02/29/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Neurofibromatosis Type 2
Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)
Recruiting
This is a prospective natural history study of CIPN in approximately 200 participants receiving taxanes (paclitaxel, docetaxel) for breast cancer, bortezomib for multiple myeloma, oxaliplatin-based regimens for colorectal cancer, or vincristine for lymphoma.. Demographic data, medical history, electronic PROs, ClinROs blood biomarkers including NF-L, PGx DNA analyses and Bedside-QST will be assessed at Baseline. The Observation Period will initiate with the first dose of chemotherapy and conclud... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Alpha Oncology Research LLC, DeBary, Florida
Conditions: Chemotherapy-induced Peripheral Neuropathy