Florida is currently home to 3730 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Rock Steady Boxing: A Community Based In Person Class
NCT05773612
Recruiting
The purpose of this study is to evaluate the feasibility and effectiveness of a non-contact Rock Steady Boxing class delivered to participants with Parkinson's Disease via an in-person community-based program. The study will also assess the overall feasibility of integrating an in-person community program within a neuromuscular course in a Doctor of Physical Therapy program. Specific Aim: To examine the effects of an in-person community-based Rock Steady Boxing class on the functional mobility,... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/06/2023
Locations: University of St Augustine for Health Science, Miami, Florida
Conditions: Parkinson Disease
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A Community-Based Falls Prevention Program for Adults At-Risk for Falls
NCT05771818
Recruiting
The goal of this interventional study is to implement a Falls Prevention Program to impact the risk and injuries related to falls. The main question is to learn and examine the effects of a falls prevention program on the functional mobility of adults at risk for falls. Participants will: * Complete functional mobility assessments * Complete Falls prevention obstacle course training * Complete Falls Strategies Training * Complete walking and balance training
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/05/2023
Locations: University of St Augustine for Health Science, Miami, Florida
Conditions: Accidental Fall, Neurologic Disorder, Old Age; Debility, Healthy Aging
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Navtemadlin (KRT-232) With or Without Anti-PD-1/Anti-PD-L1 for the Treatment of Patients With Merkel Cell Carcinoma
NCT03787602
Recruiting
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Merkel Cell Carcinoma (MCC) who have failed treatment with at least one anti-PD-1 or anti-PD-L1 immunotherapy or in combination with avelumab in MCC patients who are anti-PD-1 or anti-PD-L1 treatment naïve. Inhibition of MDM2 is a novel mechanism of action in MCC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Merkel Cell Carcinoma
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Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis
NCT05694195
Recruiting
This is a multi-center, open-label, parallel-group study to evaluate oral doses of INCB054707 in participants with varying levels of renal function or impairment.
Gender:
All
Ages:
Between 18 years and 82 years
Trial Updated:
02/17/2023
Locations: Orlando Clinical Research Center, Orlando, Florida
Conditions: Renal Insufficiency, Kidney Diseases
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Registry Study for Proton Therapy Clinical Outcomes and Long-Term Follow-up
NCT02070328
Recruiting
Proton therapy is a limited medical resource that is more expensive than conventional x-ray therapy. To correctly measure the success of proton therapy in treating different conditions, it is important to check a patient's health status after their treatment is finished. Checking on the progress of patients over many years (called long-term follow-up) is needed because the long-term effects of proton therapy are not well known.
Gender:
ALL
Ages:
All
Trial Updated:
02/06/2023
Locations: Ackerman Cancer Center, Jacksonville, Florida
Conditions: Cancer
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CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer
NCT05210283
Recruiting
The CORRECT - MRD II study will prospectively enroll patients who have undergone complete surgical resection for stage II or III colorectal cancer. Patients will be followed for a minimum of 3 years and up to 5 years for recurrence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/01/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Colorectal Cancer
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Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
NCT05369546
Recruiting
The objective is to better identify suspicious breast lesions that need to be biopsied for malignancy in women currently recommended for biopsy. The long-term goal is to reduce unnecessary biopsies and increase biopsy yield. To do this, the investigators have developed an innovative way to use FDA-approved breast imaging protocols to acquire multispectral images to measure the composition of suspicious breast lesions. The central hypothesis is that breast tissue composition in combination with a... Read More
Gender:
FEMALE
Ages:
Between 20 years and 85 years
Trial Updated:
01/31/2023
Locations: H. Lee Moffitt Cancer Center & Research Institute, Inc., Tampa, Florida
Conditions: Breast Cancer
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TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
NCT05698576
Recruiting
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia. It will assess the tolerance and safety of target fusion ablation of prostate cancer tumors using Laser Induced Thermal Therapy (TFA-LITT) guided by fusion imaging in men 50 to 80 years of age with low to intermediate risk prostate cancer Prostate Cancer is currently managed with in a discrete fashion where patients either enroll in active surveillanc... Read More
Gender:
MALE
Ages:
Between 50 years and 80 years
Trial Updated:
01/24/2023
Locations: Urology Specialist Group, Hialeah, Florida
Conditions: Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound, Sexual Function Disturbances, Urinary Incontinence, Urinary Function Disorders, Prostate Biopsy, Ablation
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MRI/Ultrasound Fusion Guided Laser Ablation of Prostate Cancer
NCT05241236
Recruiting
This serves as a registration trial. It aims to record short, intermediate, and long-term outcomes of patients treated with targeted laser ablation of biopsy confirmed prostate cancer. Outcomes will be categorized as: 1- Procedure Related, 2- Perioperative - Adverse Events that may occur within 90 days, 3-Oncologic: Recurrence of cancer in treatment area, de-novo tumors, conversion to radical surgery, radiation or cryoablation, emergence of metastasis, 4- Functional: Sexual and Urinary function... Read More
Gender:
MALE
Ages:
50 years and above
Trial Updated:
01/24/2023
Locations: Urological Research Network, Miami Lakes, Florida
Conditions: Neoplasms Prostate, Cancer of the Prostate
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Cryaoablation Assisted Partial Nephrectomy a Non Ischemic Approach
NCT05218811
Recruiting
Patients with renal masses eligible to partial nephrectomy often require arterial ischemia to control or prevent blood loss during this surgical procedure. This study aims to determine the safety and efficacy of renal cryoablation at the tumor bed, as a substitute measure or technique vs total or selective arterial renal ischemia.
Gender:
ALL
Ages:
Between 55 years and 65 years
Trial Updated:
01/24/2023
Locations: Urological Research Network, Miami Lakes, Florida
Conditions: Kidney Neoplasms
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MRI/Ultrasound Fusion Guided Prostate Cryotherapy
NCT02381990
Recruiting
Registration of Prostate Cancer patients undergoing Prostate Cryotherapy guided by Mutiparametric-MRI (MP-MRI) highlighting biopsy confirmed regions. The primary outcome measure is 5 year oncological control. Secondary aim is lack of progression beyond the prostate gland. The aim of intervention is to eradicate prostate cancer disease in the treated area while imposing no or minimal deleterious effects in quality of life.
Gender:
MALE
Ages:
55 years and above
Trial Updated:
01/24/2023
Locations: Urological Research Network, Miami Lakes, Florida
Conditions: Neoplasms Prostate, Cancer of the Prostate
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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
NCT01696721
Recruiting
In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that... Read More
Gender:
ALL
Ages:
21 years and below
Trial Updated:
01/05/2023
Locations: University of Florida Health Proton Therapy Institute, Jacksonville, Florida
Conditions: Pediatric Patients Treated With Radiation Therapy
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