Maryland is currently home to 2854 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Recruiting
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C). The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window
Gender:
All
Ages:
All
Trial Updated:
02/10/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Charcot Marie Tooth Disease
Multi-Reader, Multi-Case, Cross-Over, Retrospective Study to Evaluate Effectiveness of Lunit INSIGHT DBT
Recruiting
This study aims to evaluate Effectiveness of Lunit INSIGHT DBT in the assistance of detection and diagnosis of breast cancer during 3D mammography interpretation
Gender:
Female
Ages:
22 years and above
Trial Updated:
02/09/2023
Locations: Anne Arundel Medical Center, Annapolis, Maryland
Conditions: Breast Cancer
Real World Observational Study of Poteligeo in Adult Patients With MF and SS (PROSPER)
Recruiting
This is a prospective, observational, non-interventional, international, multi-center, mixed methods study that will involve the integration of quantitative and qualitative data in patients with MF/SS treated with Poteligeo.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: The Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Mycosis Fungoides and Sézary Syndrome
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (AMD) or Subjects With Diabetic Macular Edema (DME)
Recruiting
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in subjects with Neovascular (wet) Age-Related Macular Degeneration (AMD) or subjects with Diabetic Macular Edema (DME)
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: Cumberland Valley Retina Consultants, Hagerstown, Maryland
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD
Recruiting
The Ischemia-IMT (Ischemia-Intensive Medical Treatment Reduces Events in Women with Non-Obstructive CAD), subtitle: Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR) trial is a multicenter, prospective, randomized, blinded outcome evaluation (PROBE design) evaluating intensive statin/ACE-I (or ARB)/aspirin treatment (IMT) vs. usual care (UC) in 4,422 symptomatic women patients with symptoms and/or signs of ischemia but no obstructive CAD. The hypothesis is that IMT will re... Read More
Gender:
Female
Ages:
Between 18 years and 100 years
Trial Updated:
02/09/2023
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Coronary Artery Disease
Identify the Usefulness of In-person and Virtual Quit Smoking Programs
Recruiting
This study is a randomized community-based trial adapted to the needs of adults aged 21 years or older that is designed by an existing research partnership called Communities Engaged and Advocating for Smoke-free Environments (CEASE). The overarching goal of the proposed study is to apply a community-based approach to reduce tobacco use among low-income communities in Baltimore City. The study setting represents three underserved communities in Baltimore City: the Oldtown/Middle East, the Waverl... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
02/08/2023
Locations: Morgan CARES, Baltimore, Maryland
Conditions: Cigarette Smoking, Tobacco Use
Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
Recruiting
Study of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2023
Locations: University of Maryland Greenebaum Cancer Center, Baltimore, Maryland
Conditions: Mesothelioma, Glioblastoma, Renal Cell Carcinoma, Non Small Cell Lung Cancer, Melanoma, Pancreatic Ductal Adenocarcinoma, Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Cholangiocarcinoma, Breast Cancer, Ovarian Cancer, Cervical Cancer, Endocervical Cancer, Colorectal Cancer, Esophageal Cancer
A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared to CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid
Recruiting
The purpose of this study is to compare the superiority of CHF 1535 compared to CHF 718 in subjects with asthma on medium or high dose inhaled corticosteroids.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/07/2023
Locations: Chiesi Clinical Trial Site 840824, White Marsh, Maryland
Conditions: Asthma
Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers
Recruiting
Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/07/2023
Locations: Maryland Oncology Hematology, Rockville, Maryland
Conditions: Ovarian Cancer, Ovarian Carcinoma, Ovary Cancer, Endometrial Cancer, Endometrioid Adenocarcinoma, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
Study of Descartes-30 in Acute Respiratory Distress Syndrome
Recruiting
Emergency study to test the safety of Descartes-30 cells in patients with moderate-to-severe acute respiratory distress syndrome (ARDS) AND COVID-19
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: University of Maryland Medical Center Medical Center, Baltimore, Maryland
Conditions: Acute Respiratory Distress Syndrome, Covid19
Study of Infigratinib in Children With Achondroplasia
Recruiting
This is a Phase 2, multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, tolerability, and efficacy of infigratinib, a fibroblast growth factor receptor (FGFR) 1-3-selective tyrosine kinase inhibitor, in children 3 to 11 years of age with Achondroplasia (ACH) who previously participated in the PROPEL study (Protocol QBGJ398-001) for at least 6 months. The study includes dose escalation with extended treatment, and dose expansion. The study also includes a PK S... Read More
Gender:
All
Ages:
Between 3 years and 11 years
Trial Updated:
02/06/2023
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Achondroplasia
The PROMISE Study: Duavee in Women With DCIS
Recruiting
The main purpose of this study is to determine if taking the study drug, conjugated estrogens/bazedoxifene (Duavee®) causes any changes in the proliferation markers within the breast tissue of the study subjects. The study drug is approved by the US Food and Drug Administration in healthy postmenopausal women to treat certain symptoms of menopause such as hot flashes. Since it is not approved in women with DCIS, its use in this study is experimental. This study will also look at whether taking t... Read More
Gender:
Female
Ages:
Between 18 years and 79 years
Trial Updated:
02/06/2023
Locations: John's Hopkins University, Baltimore, Maryland
Conditions: Ductal Breast Carcinoma In Situ, Postmenopausal