Maryland is currently home to 2865 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Phase 2 Safety and Immunogenicity Study of Rift Valley Fever Vaccine
NCT03609398
Recruiting
This study is to collect safety and immunogenicity data for an Rift Valley Fever (RVF) vaccine
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/10/2021
Locations: Special Immunization Program, Division of Medicine, USAMRIID, Fort Deterick, Maryland
Conditions: Rift Valley Fever
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Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage Response
NCT04692662
Recruiting
Background: People with advanced cancer are usually treated with surgery, radiation, immunotherapy drugs, or chemotherapy drugs. Talazoparib is a type of drug called a PARP inhibitor. It prevents DNA repair and has shown anticancer activity in early clinical trials. Researchers want to learn more about how it works in different types of patients. Objective: To find out how talazoparib works in tumor cells and if it works differently in people who have or have not already been treated with ano... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2021
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Solid Tumors
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Assessment of Self-Collected Sample Compared to Clinician Collected Sample in COVID-19 and Influenza Program
NCT04681950
Recruiting
We are trying to see whether a self-collected saliva swab in the home setting is as good as or better than a study clinician-collected anterior nose swab in evaluating whether you are positive for COVID-19 or Influenza A/Influenza B. You may have no symptoms, so you may be positive and capable of spreading the infection to others and you don't know it. Knowing whether you are positive is important because you would have to quarantine and not go out to prevent spreading the infection to others.
Gender:
All
Ages:
All
Trial Updated:
12/22/2020
Locations: Biocerna LLC, Fulton, Maryland
Conditions: Subjects Possibly Exposed to COVID-19
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Spinal Cord Injury Registry - North American Clinical Trials Network
NCT00178724
Recruiting
The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI). Information will be collected on the natural history of SCI and course of treatment through the first 12 months from the date of injury or long as medically indicated. Data collected includes imaging information from CT or MRI scans, neurological a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/22/2020
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Spinal Cord Injury
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Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
NCT04519099
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: CBH Health LLC, Gaithersburg, Maryland
Conditions: Schizophrenia
Register for Updates
Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: University of MD Medical Group, PA, Baltimore, Maryland
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
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Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair
NCT02803957
Recruiting
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Gender:
All
Ages:
21 years and above
Trial Updated:
12/04/2019
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Mitral Valve Insufficiency
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Treatment of Leishmaniasis With Impavido® (Miltefosine): Pregnancy Registry
NCT02427308
Recruiting
The purpose of this observational study is to fulfill FDA Post Marketing Requirement (PMR) 2127-1 for miltefosine (NDA204684): implement a pregnancy registry for the time period Mar 2015-Mar 2024. This study is a prospective observational study in which female patients undergoing Impavido who become pregnant during treatment or within 5 months after completing treatment can volunteer to provide information about their pregnancy and the outcome of the pregnancy.
Gender:
Female
Ages:
All
Trial Updated:
03/06/2018
Locations: Fast Track, North Potomac, Maryland
Conditions: Leishmaniasis or Other Uses of Miltefosine
Register for Updates
Exercise and Brain Health
NCT02626442
Recruiting
The risk of stroke and vascular dementia is high in individuals who have had a prior stroke or TIA, and in those who have vascular disease risk factors, such as high blood pressure, abnormal cholesterol, diabetes or pre-diabetes. These vascular risk factors can improve with exercise. This study will examine the impact of a 6 month, low intensity group exercise class on fitness, walking, balance, and brain health. This study will also collect fitness, walking, balance, and brain health outcome m... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
10/28/2016
Locations: Baltimore VA Medical Center, Baltimore, Maryland
Conditions: Stroke, Cardiovascular Risk Factors, Transient Ischemic Attack (TIA)
Register for Updates