Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Nerve Transfer to Improve Function in High Level Tetraplegia
Recruiting
The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury. Participants will: * undergo standard of care pre- and post-op testing and study exams * complete pre- and post-questionnaires * undergo standard of care nerve transfer surgeries * follow-up with surgeon at 6/12/18/24/36 and potentially at 48 months * attend therapy at local therapist for up to 2 years p... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/11/2024
Locations: University of Miami, Miami, Florida
Conditions: Cervical Spinal Cord Injury, Tetraplegia
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Recruiting
The objective of this study is to collect information on patients with cardiomyopathy (CM) due to mutations in the MYBPC3 gene, to evaluate their disease course, burden of illness, risk factors for this disease, and the quality of life (QoL). This study will also collect information on treatments, procedures and outcome in infants and children up to 18 yrs who have this mutation.
Gender:
ALL
Ages:
Between 0 years and 18 years
Trial Updated:
11/11/2024
Locations: Joe DiMaggio Children's Hospital, Hollywood, Florida
Conditions: Cardiomyopathy
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
Recruiting
This is a study of the efficacy and safety of BXCL501 in children and adolescents with acute agitation and either bipolar disorder or schizophrenia.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
11/11/2024
Locations: Bioxcel Clinical Research Site, Hialeah, Florida
Conditions: Schizophrenia, Schizo-Affective Disorder, Schizophreniform; Schizophrenic, Bipolar Disorder I, Bipolar Disorder II
A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old
Recruiting
Gastroesophageal reflux disease (GERD) is caused by food or acid coming up from the stomach into the esophagus, repeatedly. The esophagus is the tube that carries food and liquids from the mouth to the stomach. The body uses stomach acid to break down food, but when acid rises up into the esophagus it can hurt or damage it. People with GERD often feel food coming back up into the throat and mouth and have a burning feeling in their stomach, chest, or throat, called heartburn. Other symptoms of... Read More
Gender:
ALL
Ages:
Between 2 years and 11 years
Trial Updated:
11/11/2024
Locations: D&H National Research Centers, Miami, Florida
Conditions: Gastroesophageal Reflux Disease (GERD)
Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome
Recruiting
This study compares the efficacy of Tamibarotene in combination with azacitidine to azacitidine in combination with placebo in participants who are Retinoic Acid Receptor Alpha (RARA) positive, and newly diagnosed with higher-risk myelodysplastic syndrome (HR-MDS), and who have not received treatment for this diagnosis. The primary goal of the study is to compare the complete remission rate between the two treatment arms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Cancer specialists of North Florida, Jacksonville, Florida
Conditions: Myelodysplastic Syndromes
StrataMGT in the Reduction of Vulvar Lichen Sclerosus (LS) Symptoms
Recruiting
This study is designed to evaluate the efficacy and safety of StrataMGT for the management of vulvar lichen sclerosus symptoms.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/07/2024
Locations: Centers for Vulvovaginal Disorders, FL, Tampa, Florida
Conditions: Vulvar Lichen Sclerosus
Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms
Recruiting
The main purpose of this study is to determine the effectiveness of the study drug pacritinib in people with relapsed or refractory lymphoproliferative disorders.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: T-Cell Neoplasm, Lymphoproliferative Disorders
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
Recruiting
The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.
Gender:
ALL
Ages:
All
Trial Updated:
11/07/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Congenital Disorders of Glycosylation
Comprehensive SRS Regenerex Tissue Attachment
Recruiting
The objective of this retrospective and prospective consecutive series data collection is to confirm safety, performance, and clinical benefits of the Comprehensive SRS Regenerex Tissue Attachment Augments when used for limb salvage arthroplasty.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/06/2024
Locations: Toman Orthopedics and Sports Med, Boca Raton, Florida
Conditions: Arthroplasty Complications, Osteo Arthritis Shoulders
Diagnostic Odyssey: Whole Genome Sequencing (WGS)
Recruiting
The goal of this collaborative research is to study human genomes in children with suspected congenital disease, multiple-congenital anomalies and/or multi-organ disease of unknown etiology by understanding the potential value of Whole Genome Sequencing (WGS) in establishing genetic diagnosis. The study will examine diagnosis rates, changes in clinical care as a result of a genetic diagnosis, health economics including potential cost-effectiveness of WGS and patient and provider experience with... Read More
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/06/2024
Locations: Nickalus Children's Hospital f/k/a Miami Children's Hospital, Miami, Florida
Conditions: Genetic Disease, Genetic Syndrome
FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma
Recruiting
The goal of this FID-007 Clinical Trial is to compare the efficacy of different dosing regimens of FID-007 in combination with Cetuximab in patients with recurrent or metastatic Head and Neck Squamous Cell Carcinoma (HNSCC). The main questions it aims to answer are: to evaluate the efficacy, and to characterize the safety and tolerability. Eligible participants will be enrolled and randomized to 1 of 2 arms of FID-007 with fixed-dose Cetuximab in each 28-day cycle.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/05/2024
Locations: Moffitt Cancer Center Magnolia Campus, Tampa, Florida
Conditions: Head and Neck Squamous Cell Carcinoma
Customized TULSA-PRO Ablation Registry
Recruiting
This patient registry will capture data from patients who have been or who are undergoing the transurethral ultrasound ablation (TULSA) procedure as part of their routine clinical care. The registry will shed light on real-world outcomes of safety and efficacy of the procedure and understand how a patient's quality of life is affected throughout their follow-up and lifetime.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/05/2024
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Prostate Cancer, Prostate Adenocarcinoma, Benign Prostatic Hyperplasia