Florida is currently home to 3829 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study to Evaluate Efficacy and Safety of Light Dose in Subjects with PWB Treated with Hemoporfin PDT
Recruiting
This is a multi-center, randomized, double-blind, vehicle-controlled, and sequential group Phase 2 study. Eligible subjects aged 18 to 65 years old with PWB of face and/or neck area (except subjects for Stage One) will receive Hemoporfin PDT or vehicle PDT in 8-week cycles at fixed drug dose (5 mg/kg) and different light fluence.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/24/2024
Locations: Skin and Cancer Associates (SCA) and the Center for Cosmetic Enhancement (CCE), Aventura, Florida
Conditions: Port-Wine Stain, Nevus Flammeus, Port-wine Birthmarks
Preventing Alzheimer's With Cognitive Training
Recruiting
Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residentia... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
09/24/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: All Children's Research Institute, Saint Petersburg, Florida
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
INNOVEN: Efficacy of Porcine Placental Extracellular Matrix Plus Standard of Care (SOC) Versus SOC Alone
Recruiting
INNOVEN is a multi-center randomized controlled clinical trial to evaluate the efficacy of porcine placental extracellular matrix (PPECM) and standard of care (SOC) versus SOC alone in the closure of non-healing venous leg ulcers (VLUs).
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/23/2024
Locations: Three Rivers Wound and Hyperbaric Center, North Port, Florida
Conditions: Wound Heal, Venous Leg Ulcer
Frataxin mRNA in Biofluids
Recruiting
The purpose of this research study is to determine a way to measure frataxin messenger RNA (mRNA) in fluids such as blood and cerebrospinal fluid (CSF) from patients with Friedreich's ataxia (FRDA). The gene mutation in FRDA leads to low levels of the mRNA and then low levels of the protein frataxin that leads to the disease. Treatments being developed for FRDA have the ability increase these levels including in brain where it is needed. Currently, there is no accepted way to measure frataxin pr... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/23/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Friedreich Ataxia
Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
Recruiting
The trial is an open-label randomized study that will examine whether switching to a selective IL23 inhibitor (guselkumab) is more effective than switching to a second TNFi (golimumab) among patients with PsA who have an inadequate response to a TNFi.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/23/2024
Locations: Family Arthritis Center, Loxahatchee Groves, Florida
Conditions: Psoriatic Arthritis
Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures
Recruiting
The rapid increase of electronic nicotine delivery systems (ENDS) use by young people in the US and their potential to harm health, cause addiction, and serve as a risk for cigarette smoking or dual-use is alarming. The epidemic of ENDS use among young people in the US has been associated with the rise in popularity of ENDS products that are very efficient in delivering high doses of nicotine to users. Therefore, the investigators propose to study the effects of nicotine reduction (NR) on young... Read More
Gender:
ALL
Ages:
Between 21 years and 35 years
Trial Updated:
09/23/2024
Locations: Florida International University, Miami, Florida
Conditions: Electronic Cigarette Use
A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors
Recruiting
Part 1 of this study is an open-label, dose-escalation, and safety expansion study of an anti-LILRB2 / anti-PD-L1 bispecific antibody SPX- 303 in patients with solid tumors. Part 2 of this study is an indication-specific dose expansion study of SPX-303.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Solid Tumor, HNSCC, RCC, CRC
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
Recruiting
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question:... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Diverticulitis
Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Univ of Miami School of Medicine, Miami, Florida
Conditions: HIV Infections
Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
Recruiting
The goal of this clinical trial is to learn if a modification to metaxalone 640 mg can reduce low back and leg pain. The participants will be 18 to 80 years old, healthy with newly occurring back or leg pain. The main question aims to compare a group taking active treatment and a group taking a look-alike substance containing no active treatment. All participants will answer questions on Day 1, before treatment, and on 7-day after treatment, about: * Amount and quality of pain * Interference wi... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/19/2024
Locations: Arthritis and Osteoporosis Center, Aventura, Florida
Conditions: Sciatica Acute, Lumbar Spinal Stenosis
The PANTHERS (Parents and iNfants Together in Home-based Early Remote Services) Project
Recruiting
The PANTHERS (Parents And iNfants Together in Home-based Early Remote Services) Projects is a study funded by the National Institute of Child Health and Human Development to evaluate the efficacy and maintenance of a remote home-based preventive intervention, the Infant Behavior Program (IBP), to decrease behavior problems in infants from high-risk families. All families will participate in five remote evaluations in their home, and families will also receive 6 remote treatment sessions of eithe... Read More
Gender:
ALL
Ages:
Between 12 months and 18 months
Trial Updated:
09/19/2024
Locations: South Miami Children's Clinic, Miami, Florida
Conditions: Early Childhood Development, Behavior Problems