Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study
NCT06312722
Recruiting
The goal of this clinical trial is to verify the continued safety and effectiveness for the Optilume BPH Catheter System.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
11/04/2024
Locations: Florida Urology Partners, LLP, Tampa, Florida
Conditions: Benign Prostatic Hyperplasia
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A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors
NCT06190886
Recruiting
The goal of this clinical trial is to evaluate the safety and tolerability of escalating doses of PTX-912 in patients with locally advanced or metastatic solid tumors. To evaluate the PK and immunogenicity profile of PTX-912. To evaluate the preliminary anti-tumor activity of PTX-912. Participants will be treated with PTX-912 via iv infusion, every 2 weeks until progression of disease, unacceptable toxicity, or 12 months of total study therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: University of Miami, Miami, Florida
Conditions: Advanced Cancer, Solid Tumor, Metastatic Cancer
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Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD
NCT05380050
Recruiting
Veterans with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) commonly experience cognitive impairments including attention and executive function deficits that interfere with their ability to engage in productive personal and social activities. Of the limited interventions available to address cognition, none rigorously train attention beyond strategy management. This study will evaluate an innovatively combined strategy training known as Goal Management Training pl... Read More
Gender:
ALL
Ages:
Between 30 years and 55 years
Trial Updated:
11/04/2024
Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida
Conditions: Brain Injury, Cognition, PTSD, Intervention
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Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment
NCT06535399
Recruiting
The purpose of this study is to assess the drug levels and safety of golcadomide (BMS-986369) in adult participants with moderate and severe Hepatic Impairment (HI), and in matched healthy control participants with normal hepatic function.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/01/2024
Locations: Local Institution - 0005, Orlando, Florida
Conditions: Hepatic Impairment, Healthy Volunteers
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ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
NCT05682443
Recruiting
In this Phase 2 study, mCRPC patients with PSMA positive scans who progressed on prior ARTA and up to 2 lines of taxanes, and are naïve to lutetium Lu 177 vipivotide tetraxetan, will be enrolled. The study is open-label, randomized with active control, multi-center study.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: Moffitt Cancer Cancer- 1605, Tampa, Florida
Conditions: Metastatic Castration-resistant Prostate Cancer
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Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma
NCT04696731
Recruiting
This is a Phase 1 dose escalation study following a 3+3 study design. The purpose of the TRAVERSE study is to assess the safety, efficacy, and cell kinetics of ALLO-316 in adults with advanced or metastatic clear cell renal cell carcinoma after a lymphodepletion regimen comprising fludarabine, cyclophosphamide, and ALLO-647 to define a Phase 2 dose.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/30/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Advanced/Metastatic Clear Cell Renal Cell Carcinoma
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LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm
NCT04695171
Recruiting
The cohort registry is both retrospective and prospective, multicenter surveillance of subjects who underwent a prior hiatal hernia repair and Magnetic Sphincter Augmentation or fundoplication construction more than 2 years prior to initial study visit.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
10/30/2024
Locations: South Florida Reflux Center, Coral Springs, Florida
Conditions: Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Reflux, Gastroesophageal, Reflux Acid
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Evaluate the Safety and Clinical Activity of HH2853
NCT04390737
Recruiting
This is an open-label, multicenter, first-in-human phase I/II study which is composed of 3 parts: phase I dose escalation, phase I dose extension and phase II. HH2853 will be administered orally on a continuous BID schedule on a continuous 28-day treatment cycle.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/30/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Advanced Solid Tumor, FL Lymphoma, Epithelioid Sarcoma, Peripheral T Cell Lymphoma
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DermaSensor Postmarket Surveillance Study
NCT06666790
Recruiting
The objective of this study is to evaluate the sensitivity of the DermaSensor device and Investigators when used on skin lesions concerning for melanoma.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/29/2024
Locations: Velocity, New Smyrna Beach, Florida
Conditions: Melanoma, Skin
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Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer
NCT06631521
Recruiting
The goal of this clinical trial is to determine the safety and feasibility of a new combination of darolutamide and relugolix as neoadjuvant therapy preceding radical prostatectomy (RP) for high-risk prostate cancer (PCa) in adult males.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: AdventHealth Orlando, Orlando, Florida
Conditions: Prostate CA, Prostate Cancer (Adenocarcinoma), Prostate Cancer Surgery
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Integrative Breathwork Intervention for Chronic Pain
NCT06546956
Recruiting
The proposed research is to develop and refine a multicomponent breathwork intervention, Guided Respiration Mindfulness Therapy, and to iteratively evaluate its feasibility, acceptability, and plausibility for clinically significant effects in people with chronic low back pain. This integrative breathwork intervention involves a 60-minute breathing session where the focus is to maintain a conscious connected breathing pattern (no pause between inhale and exhale), apply mindful acceptance to soma... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/29/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Chronic Low-back Pain
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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
NCT05929768
Recruiting
This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be bette... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: The Watson Clinic, Lakeland, Florida
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma
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