Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Efficacy of Distal Pharyngeal Airway for Oxygenation During TEE
Recruiting
The purpose of this study is to investigate the effect of using the McMurray Enhanced Airway (MEA) which is a flexible extended-length distal pharyngeal airway on improving oxygen delivery compared to standard nasal cannula.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/28/2024
Locations: Jackson Memorial Hospital, Miami, Florida
Conditions: Airway Obstruction
Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma
Recruiting
This study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called REGN2810, also known as cemiplimab (each individually called a "study drug" or called "study drugs" when combined). The study is focused on patients with a type of skin cancer known as melanoma. The aims of the study are to see how effective the combination of fianlimab and cemiplimab are in treating the melanoma skin cancer, in comparison with a medicati... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
10/28/2024
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Melanoma
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
Recruiting
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
10/25/2024
Locations: Bauman Medical, Boca Raton, Florida
Conditions: Post Procedural Erythema
PUSH-IT Continuing Enteral Feeds for Tracheostomy
Recruiting
The goal of this clinical trial is to evaluate nutrition administration in the time around the tracheostomy in patients with breathing tubes. The main questions it aims to answer are: * Will continuing nutrition up to the time of surgery (tracheostomy) decrease nutrition interruptions, thereby increasing food intake? * Does continuing nutrition up to the time of surgery increase instances of food going into the lungs or lung infections? Researchers will compare patients who have nutrition with... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: St. Mary's Medical Center, West Palm Beach, Florida
Conditions: Tracheostomy Complication, Critical Illness, Nutritional Deficiency
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
The study is a randomized trial of two different screening methods for early detection of liver cancer in patients with cirrhosis of the liver. The goal of PREMIUM is to compare an abbreviated version of the diagnostic gold standard for HCC (aMRI) +AFP to the standard-of-care screening (US+AFP) in patients at high risk of developing HCC. The investigators hypothesize that HCC will be detected at earlier stages, allowing for more curative treatments and resulting in a reduction in HCC-related mor... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/24/2024
Locations: James A. Haley Veterans' Hospital, Tampa, FL, Tampa, Florida
Conditions: Carcinoma, Hepatocellular, Cirrhosis
A Study of Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma
Recruiting
This phase 3 randomized, open-label multicenter trial will compare the efficacy, safety and the impact on health-related quality of life (HR-QoL) of SPd versus EloPd in pomalidomide-naïve patients with MM who have received 1 to 4 prior anti-MM regimens and been treated with an immunomodulatory imide drug (IMiD), proteasome inhibitor (PI) and an anti-CD38 monoclonal antibody (mAb).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Baptist Health South Florida, Delray Beach, Florida
Conditions: Multiple Myeloma
Single or Repeated Intravenous Administration of umbiliCAl Cord Mesenchymal sTrOmal Cells in Ischemic Cardiomyopathy
Recruiting
This is a Phase IIA, randomized, double blind, placebo controlled, multicenter study designed to assess the safety, feasibility, and efficacy of umbilical cord derived mesenchymal stromal cells (UC MSCs), administered intravenously (IV) as a single dose or repeated doses, in patients with ischemic cardiomyopathy (ICM).
Gender:
ALL
Ages:
Between 21 years and 85 years
Trial Updated:
10/23/2024
Locations: University of Miami Miller School of Medicine, Miami, Florida
Conditions: Ischemic Heart Disease
Fasting ENHANCE Pilot Study
Recruiting
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable manner in at risk overweight older adults. Specifically, this study will evaluate whether TRE can improve cognitive and physical function, as well as self-reported sleep, mood, and quality of life, in overweight, older adults (age \> 65 years) who are at high risk of co... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
10/23/2024
Locations: Clinical and Translational Research Building - Institute on Aging Suite, Gainesville, Florida
Conditions: Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease
ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST
Recruiting
The purpose of this research is to test if mutations (changes in DNA) in exons (segment of DNA or RNA containing information that has the instructions for making proteins) in the KIT gene can be used to predict the body's response to standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2024
Locations: University of Miami, Miami, Florida
Conditions: Gastrointestinal Stromal Tumors
PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence
Recruiting
Flotufolastat F-18, sold under the brand name Posluma, is a radioactive diagnostic agent for use with positron emission tomography (PET) imaging for prostate cancer. The research is being done to study the capability of 18F-rhPSMA-7.3 (flotufolastat F-18) PET scan to detect prostate cancer when there are very low levels of Prostate-Specific Antigen (PSA) following previous radical prostatectomy surgery.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/22/2024
Locations: AdventHealth, Orlando, Florida
Conditions: Prostate Cancer (Post Prostatectomy)
CARE: Cancer Risk Perception and Women of Color
Recruiting
This study examines patient understanding of current and lifetime risk for breast cancer in women of color from diverse racial and ethnic backgrounds.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
10/22/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Carcinoma
HIIT Following Breast Cancer Chemotherapy
Recruiting
Chemotherapy is an effective breast cancer treatment, which helped to increase the 5-year survival rate to approximately 95%. However, breast cancer survivors have a higher risk of cardiovascular disease (CVD) due to chemotherapy than adults without cancer. Cardiovascular rehabilitation can be an effective strategy to decrease the incidence of CVD and its risk factors in this population. The proposed study may help to examine the effect and durability of a novel high-intensity interval training... Read More
Gender:
FEMALE
Ages:
Between 18 years and 85 years
Trial Updated:
10/22/2024
Locations: Integrative Cardiovascular Physiology Laboratory, University of Florida, Gainesville, Florida
Conditions: Breast Cancer