Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors
Recruiting
Part 1 of this study is an open-label, dose-escalation, and safety expansion study of an anti-LILRB2 / anti-PD-L1 bispecific antibody SPX- 303 in patients with solid tumors. Part 2 of this study is an indication-specific dose expansion study of SPX-303.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Solid Tumor, HNSCC, RCC, CRC
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
Recruiting
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question:... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Diverticulitis
Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Univ of Miami School of Medicine, Miami, Florida
Conditions: HIV Infections
The PANTHERS (Parents and iNfants Together in Home-based Early Remote Services) Project
Recruiting
The PANTHERS (Parents And iNfants Together in Home-based Early Remote Services) Projects is a study funded by the National Institute of Child Health and Human Development to evaluate the efficacy and maintenance of a remote home-based preventive intervention, the Infant Behavior Program (IBP), to decrease behavior problems in infants from high-risk families. All families will participate in five remote evaluations in their home, and families will also receive 6 remote treatment sessions of eithe... Read More
Gender:
ALL
Ages:
Between 12 months and 18 months
Trial Updated:
09/19/2024
Locations: South Miami Children's Clinic, Miami, Florida
Conditions: Early Childhood Development, Behavior Problems
To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma
Recruiting
The goal of this clinical trial is to evaluate the efficacy of using SP-002 in participants with locally advanced Basal cell carcinoma. The main question it aims to answer is what the objective response rate for a basal cell carcinoma tumor is following 1 or 3 cycles of SP-002 treatment given as an add-on to hedgehog pathway inhibitor therapy. Researchers will compare the objective response rate for treated Basal cell carcinoma tumors between 3 treatment Arms. * Arm 1 participants will receive... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2024
Locations: Research Site, Boca Raton, Florida
Conditions: Basal Cell Carcinoma
Neuroblastoma Maintenance Therapy Trial
Recruiting
Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to prevent recurrence.
Gender:
ALL
Ages:
Between 1 year and 30 years
Trial Updated:
09/18/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Neuroblastoma
Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study
Recruiting
The Active Older Adults prospective cohort study examines the effects of a park-based fitness program on cardiovascular fitness outcomes for older adults (aged 50 years and older). Duke will perform a secondary analysis of the data collected as part of the Active Older Adults prospective cohort study run by Miami-Dade County Parks and Recreation.
Gender:
ALL
Ages:
Between 50 years and 95 years
Trial Updated:
09/17/2024
Locations: Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida
Conditions: Hypertension, Overweight, Obesity, Cardiovascular Diseases, Sedentary Behavior, Low Physical Fitness
Community Park-Based Programs for Health Promotion: the Fit2Lead Prospective Cohort Study
Recruiting
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Lead prospective cohort study run by Miami-Dade County Parks and Recreation.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/17/2024
Locations: Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida
Conditions: Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension, Prehypertension, Low Physical Fitness
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
Recruiting
The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Play prospective cohort study run by Miami-Dade County Parks and Recreation.
Gender:
ALL
Ages:
Between 6 years and 14 years
Trial Updated:
09/17/2024
Locations: Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida
Conditions: Overweight, Obesity, Hypertension, Prehypertension, Anxiety, Well-being, Depression, Low Physical Fitness, Psychological
First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors
Recruiting
A Phase 1/2a First-in-Human Study of DB-1419 in Advanced/Metastatic Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/17/2024
Locations: Site USA02, Florida City, Florida
Conditions: Solid Tumor, Adult
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
Recruiting
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)
Gender:
ALL
Ages:
All
Trial Updated:
09/17/2024
Locations: Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida
Conditions: Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia
VIA Disc NP Registry 3.0
Recruiting
Registry is to observe and trend patterns of care and outcomes for patients treated with VIA Disc NP.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/16/2024
Locations: The Orthopedic Institute, Gainesville, Florida
Conditions: Discogenic Pain, Back Pain, Back Pain, Low