Illinois is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Chronic Pain in Rheumatoid Arthritis
NCT05038553
Recruiting
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Arthritis, Rheumatoid, Pain
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Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy
NCT04586166
Recruiting
SASS (Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy) will be a multicenter, prospective, randomized, single-blind non-inferiority trial.
Gender:
FEMALE
Ages:
21 years and above
Trial Updated:
04/24/2025
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Stress Urinary Incontinence, Pelvic Floor Disorders
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Motor rECovery witH eArly imagiNg In STroke
NCT04165616
Recruiting
This study will contribute to the field of stroke rehabilitation research by expanding the investigator's understanding of the neural mechanisms responsible for the development and expression of abnormal flexion synergy, a primary movement impairment due to stroke. The study will longitudinally evaluate motor tract morphology and motor impairment/function in an attempt to develop early neuroimaging-based predictors of the development of flexion synergy and its impact on reaching and hand recover... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/24/2025
Locations: Department of Physical Therapy and Human Movement Sciences, Chicago, Illinois
Conditions: Stroke
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Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer
NCT03824145
Recruiting
This multi-site study is being conducted to examine dietary and activity patterns, body composition, blood and quality of life in breast cancer patients. The study will recruit 176 women with MBC in Milwaukee (n=88) and Chicago (n=88).
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: Loyola University, Maywood, Illinois
Conditions: Metastatic Breast Cancer
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Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function
NCT06944392
Recruiting
This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Overactive Bladder (OAB)
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A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
NCT06849258
Recruiting
The goal of this study is to determine the safety and effectiveness of the FloStent, a medical device used to treat men with symptoms of Benign Prostatic Hyperplasia, compared to sham (procedure without deployment of the FloStent). All participants will undergo a flexible cystoscopy and those randomized to the treatment arm will receive the FloStent, while those randomized to the sham arm will not receive the FloStent.
Gender:
MALE
Ages:
45 years and above
Trial Updated:
04/23/2025
Locations: Duly Health, Lisle, Illinois
Conditions: Benign Prostatic Hyperplasia
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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
NCT06329401
Recruiting
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Progressive Pulmonary Fibrosis
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Surgical Approach to Uterine Septum
NCT06315582
Recruiting
The objective of this study is to determine if the use of scissors without electrosurgery is superior to bipolar electrosurgery for resection of uterine septum. The investigators will be comparing procedure-level variables such as operative time, complications, and need for additional procedures.
Gender:
FEMALE
Ages:
Between 22 years and 44 years
Trial Updated:
04/23/2025
Locations: Northwestern Medicine Prentice Women's Hospital, Chicago, Illinois
Conditions: Uterine Septum, Surgical Complication, Septum; Uterus, Treatment Side Effects, Treatment
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ALS/MND Natural History Study Data Repository
NCT05966038
Recruiting
This is a data repository for multi-site multi-protocol clinic-based Natural History Study of ALS and Other Motor Neuron Disorders (MND). All people living with ALS or other MNDs who attend clinics at the Study hospitals (sites) are offered to participate in the Study. The Sites collect so-called Baseline information including demographics, disease history and diagnosis, family history, etc. At each visit, the Sites also collect multiple disease-specific outcome measures and events. The inform... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease, PMA - Progressive Muscular Atrophy, PBP - Progressive Bulbar Palsy
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A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT05650632
Recruiting
Multiple Myeloma (MM) is a cancer of the blood's plasma cells ( blood cell). The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause bone pain, fractures, infections, weaker bones, and kidney failure. Treatments are available, but MM can come back (relapsed) or may not get better (refractory) with treatment. This is a study to determine adverse events and change in disease symptoms of ABBV-383 in adult participants with relapsed/refractory... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Hope And Healing Cancer Services /ID# 268536, Hinsdale, Illinois
Conditions: Multiple Myeloma
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Potassium Citrate and Crystal Light Lemonade
NCT05389995
Recruiting
To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Kidney Stone
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Childhood Activities Nutrition and Development Oversight
NCT05258656
Recruiting
The overall goal of this study is to understand how common conditions in childhood develop and if by providing specific health education and resources to parents/caregivers we can promote healthy development. This study will provide information and instruction on several aspects of infant care including, sleep, nutrition, building a healthy relationship with your baby, and healthy screen time use.
Gender:
ALL
Ages:
26 weeks and below
Trial Updated:
04/23/2025
Locations: Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Environmental Exposure
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