Illinois is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery
NCT03893734
Recruiting
A number of drugs used in the perioperative period may cause prolongation of the QT interval on the electrocardiogram (EKG). These drugs include inhalational agents, antiemetic agents, pain medications, and drugs used to reverse the effects of muscle relaxants. Approximately 80% of patients undergoing a general anesthetic will demonstrate significant prolongation of the QT interval on the EKG in the postanesthesia care unit (PACU) following surgery. The concern with QT interval prolongation is t... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/11/2019
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: EKG-QT Prolongation
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Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome
NCT03205995
Recruiting
The purpose of this study is to evaluate the platelet count change from baseline and safety of OMS721 in adults and adolescents with atypical hemolytic uremic syndrome (aHUS). The study will also evaluate pharmacokinetics (PK), pharmacodynamics (PD), and anti-drug antibody response (ADA).
Gender:
ALL
Ages:
12 years and above
Trial Updated:
10/17/2018
Locations: Omeros Investigational Site, Chicago, Illinois
Conditions: Thrombotic Microangiopathies, Atypical Hemolytic Uremic Syndrome
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Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
NCT02870244
Recruiting
Phase I clinical trial to determine the Phase II dose of autologous TIL 1383I TCR gene modified T Cells using a retrovirus. This is a novel National Cancer Institute (NCI) funded investigator initiated therapy for patients with advanced melanoma.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/08/2018
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Melanoma
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Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis
NCT00004317
Recruiting
RATIONALE: Congenital toxoplasmosis is an infection caused by the parasitic organism Toxoplasma gondii, and it may be passed from an infected mother to her unborn child. The mother may have mild symptoms or no symptoms; the fetus, however, may experience damage to the eyes, nervous system, skin, and ears. The newborn may have a low birth weight, enlarged liver and spleen, jaundice, anemia, petechiae, and eye damage. Giving the antiparasitic drugs pyrimethamine and sulfadiazine is standard treatm... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/13/2009
Locations: University of Chicago, Chicago, Illinois
Conditions: Toxoplasmosis
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