Illinois is currently home to 2618 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
MEASuRE: Metreleptin Effectiveness And Safety Registry
Recruiting
The study is a post-authorization, prospective, voluntary registry of patients treated with commercial metreleptin including, but not limited to, patients in the US and EEA.
Gender:
ALL
Ages:
All
Trial Updated:
11/15/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Generalised Lipodystrophy, Partial Lipodystrophy
Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development
Recruiting
The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term unti... Read More
Gender:
ALL
Ages:
30 years and below
Trial Updated:
11/14/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: DSD, 46,XY, DSD, Ovotesticular, DSD, Sex Chromosome, Disorders of Sex Development, Disorder of Sex Development, 46,XY, Disorder of Sex Development, 46,Xy, Cbx2-Related
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
Recruiting
The purpose of this study is to identify changes in heart tissue structure and biological function in patients with heart failure by performing an endomyocardial biopsy (EMB or heart biopsy) during a right heart catheterization (RHC). The ultimate goal is to use this information to develop new treatments for heart failure.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
11/14/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Heart Failure, Heart Failure With Preserved Ejection Fraction
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Recruiting
This phase III trial compares the effect of cabozantinib versus combination dabrafenib and trametinib for the treatment of patients with differentiated thyroid cancer that does not respond to treatment (refractory) and which expresses a BRAF V600E mutation. Cabozantinib is in a class of medications called receptor tyrosine kinase inhibitors. It binds to and blocks the action of several enzymes which are often over-expressed in a variety of tumor cell types. This may help stop or slow the growth... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/14/2024
Locations: OSF Saint Anthony's Health Center, Alton, Illinois
Conditions: Refractory Differentiated Thyroid Gland Carcinoma
Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)
Recruiting
The purpose of this study is to safely remove ovarian tissue in pediatric patients, who are at risk for infertility from their medical treatment, for freezing for future restoration of fertility and hormone function.
Gender:
FEMALE
Ages:
30 years and below
Trial Updated:
11/14/2024
Locations: Ann &Robert H Lurie Children's Hospital, Chicago, Illinois
Conditions: Pediatric Cancer
Ovarian Tissue Cryopreservation in Pre-Pubertal (OTC-Pre Pubertal)
Recruiting
The purpose of this study is to safely remove ovarian tissue in pre-pubertal pediatric patients, who are at risk for infertility from their medical treatment, for freezing for future restoration of fertility and hormone function.
Gender:
FEMALE
Ages:
11 years and below
Trial Updated:
11/14/2024
Locations: Ann & Robert H Lurie Childrens Hospital, Chicago, Illinois
Conditions: Cancers
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
Recruiting
The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after you take it), and efficacy (how well a study treatment works in the study) of the study medicine (called nirmatrelvir/ritonavir) for potential treatment of coronavirus disease 2019 (COVID-19). The study medicine will be given to patients under 18 years of age with COVID-19 that are not hospitalized but are at risk for... Read More
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
11/14/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: COVID-19
Pivotal Study of OCS-01 Eye Drops in Subjects with Diabetic Macular Edema (DIAMOND-1)
Recruiting
The primary objective is to evaluate the efficacy and safety of OCS 01 as compared to Vehicle in subjects with Diabetic Macular Edema (DME).
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
11/14/2024
Locations: Oculis Investigative Site: University Retina - Lemont, Lemont, Illinois
Conditions: Diabetic Macular Edema
The Pediatric ALL Evaluation and Trial
Recruiting
The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction alone.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
11/14/2024
Locations: Lurie Children's Hospital, Chicago, Illinois
Conditions: ACL Injury, ACL Tear
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
Recruiting
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an additional 10 weeks post treatment. Quality of Life questionnaires and adverse even... Read More
Gender:
ALL
Ages:
9 years and above
Trial Updated:
11/14/2024
Locations: Southern Illinois University School of Medicine, Springfield, Illinois
Conditions: Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic
Anti-mullerian Hormone Levels in Healthy Females
Recruiting
The purpose of this study is to have a better understanding of the normal blood levels of AMH in females from 0-18 years of age and how the blood AMH levels correspond to a female's reproductive development.
Gender:
FEMALE
Ages:
18 years and below
Trial Updated:
11/14/2024
Locations: Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Healthy
Pediatric Ovarian Tissue Banking - Operative Specimens From Females 0-18 Years of Age
Recruiting
A child is eligible to participate in this study because she is having surgery on her ovary. The investigators may obtain a sample of any discarded tissue from the surgery for an ovarian tissue library. This study is being conducted to understand how common ovarian conditions effect the number and quality of ovarian follicles and the reproductive potential of the ovary.
Gender:
FEMALE
Ages:
18 years and below
Trial Updated:
11/14/2024
Locations: Ann & Robert H Lurie Childrens Hospital, Chicago, Illinois
Conditions: Benign Cysts Ovarian, Cystectomy, Torsion, Malignant Cysts Ovarian