Illinois is currently home to 2681 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
NCT05538689
Recruiting
In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the potential to delay the recurrence of fibroid symptoms, prolong the improved quality of life and delay the need for re-intervention after uterine sparing surgery versus the routine standard of care.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Chicago South Loop, Chicago, Illinois
Conditions: Metrorrhagia, Pelvic Pain, Menorrhagia, Leiomyoma
Register for Updates
Transnasal Esophagoscopy (TNE) Esophageal Cancer Screening
NCT05480891
Recruiting
This research study is being done for 2 reasons: 1) The investigators want to learn about the eating, smoking and drinking habits of adults, 18 years of age and older, in various Chicago communities, and 2) the investigators want to offer screening for participants whose smoking and drinking habits put them at risk for cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Mile Square Health Center-University of Illinois Hospital, Chicago, Illinois
Conditions: Esophageal Cancer
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Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start
NCT05444582
Recruiting
This is a prospective clinical research study to test the effectiveness of the Levonorgestrel (LNG) 52 mg Intrauterine Device (IUD) for emergency contraception (EC) and same-day start use that will enroll people receiving care at Planned Parenthood affiliates across the U.S. Our prior work demonstrated efficacy (shows that it works in an ideal setting) for the LNG 52 mg IUD for these uses and this study will test effectiveness (how well it works in the real world) in a larger, heterogenous popul... Read More
Gender:
Female
Ages:
Between 16 years and 35 years
Trial Updated:
05/06/2024
Locations: Planned Parenthood Illinoi, Chicago, Illinois
Conditions: Contraception
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Nitrous Oxide as Treatment for Fibromyalgia
NCT05357066
Recruiting
The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/06/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Fibromyalgia, Central Neuropathic Pain
Register for Updates
Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis
NCT05051618
Recruiting
The purpose of this research is to examine the effects of two different exercise training regimens for managing depression and improving other health indicators among persons with multiple sclerosis (MS). The project will enroll persons with MS and major depressive disorder (MDD) between 18 and 64 years of age. The investigators will enroll a total of 146 participants. This is a Phase-II trial that compares the efficacy of an exercise training program (POWER-MS) compared with a stretching progr... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
05/05/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Multiple Sclerosis, Major Depressive Disorder
Register for Updates
Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers
NCT06403605
Recruiting
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on 2 commercially available SOC treatments for Diabetic Foot Wounds.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Gateway Clinical Trials, O'Fallon, Illinois
Conditions: Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
Register for Updates
Parent-to-parent Coaching While Awaiting Hospital Discharge With a Child With a Ventilator
NCT05880953
Recruiting
The objective of the study is to pilot a parent-to-parent coaching model with experienced family members of children with Invasive Mechanical Ventilation (IMV) as parent coaches.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Invasive Mechanical Ventilation, Children With Medical Complexity, Home Nursing, Empowerment
Register for Updates
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
NCT05719714
Recruiting
The goal of this study is to better understand the effects of a sodium-glucose transport protein 2 inhibitor, dapagliflozin, added on to standard of care on heart and lung function and circulating metabolites (substances created when our bodies break down food, drugs, or its own tissues) in patients with chronic kidney disease.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/03/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Chronic Kidney Diseases, Heart Failure With Preserved Ejection Fraction, Kidney Diseases, Heart Failure
Register for Updates
Improving Hypertension Medication Adherence for Older Adults
NCT05610059
Recruiting
This randomized controlled trial will assess the efficacy and scalability of a blood pressure technology system intervention. The investigators will enroll 224 older adults with hypertension to identify those who are nonadherent for one hypertension medication. The participants will be randomized to one of two groups (112 per group) to use the blood pressure system for 6-months. Both groups receive information about high blood pressure and medications. One group will also receive strategies that... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
05/03/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Aging, Medication Adherence, Hypertension
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Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
NCT05561387
Recruiting
This phase III trial compares three-drug induction regimens followed by double-or single-drug maintenance therapy for the treatment of newly diagnosed multiple myeloma in patients who are not receiving a stem cell transplant and are considered frail or intermediate-fit based on age, comorbidities, and functional status. Treatment for multiple myeloma includes initial treatment (induction) which is the first treatment a patient receives for cancer followed by ongoing treatment (maintenance) which... Read More
Gender:
All
Ages:
All
Trial Updated:
05/03/2024
Locations: Saint Anthony's Health, Alton, Illinois
Conditions: Plasma Cell Myeloma
Register for Updates
Accurate, Rapid and Inexpensive MRI Protocol for Breast Cancer Screening
NCT04877912
Recruiting
The purpose of this study is to test an innovative MRI breast cancer screening method in women with mammographically dense breasts as well as other women with moderately increased cancer risk. MRI, combined with other methods of risk assessment, has potential to significantly improve sensitivity to cancer in dense breasts and detect cancer in all cases at a much earlier stage, with far fewer interval cancers than mammography. Previous tests of MRI sensitivity show that this screening could signi... Read More
Gender:
Female
Ages:
Between 40 years and 74 years
Trial Updated:
05/03/2024
Locations: University of Chicago Mitchell Hospital, Chicago, Illinois
Conditions: Breast Cancer
Register for Updates
Perioperative Nutritional Optimization in Head and Neck Cancer Patients
NCT04449445
Recruiting
To determine whether nutritional optimization in head and neck cancer patients undergoing major surgery will decrease post-operative wound complications. The Investigators hypothesize that nutritional supplementation with Nestle Impact Advanced Recovery (AR) will decrease the rate of wound complications after surgery
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Head and Neck Cancer
Register for Updates